Food safety assessment of genetically modified crops

Agronomy Journal

Volumn 92, Issue 4, 2000, Pages 793-797

  Kaeppler, Heidi F ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC RESISTANCE; FOOD SAFETY; GENETIC ENGINEERING; GENETICALLY MODIFIED FOOD; RISK ASSESSMENT; TRANSGENIC PLANT; UNITED STATES;

EID: 0033929526     PISSN: 00021962     EISSN: None     Source Type: Journal    
DOI: 10.2134/agronj2000.924793x     Document Type: Article

References (29)

1. American Soybean Association. 1999. ASA confirms the natural variability in isoflavones in soybeans. [Online.] Available at http:// amsoy.org/documenls/isobkgndr.htm (verified 24 Apr. 2000).
2. Calgene. 1990. Request for advisory opinion - kan gene: Safety and use in the production of genetically engineered plants. FDA Docket 90A-0416. FDA. Rockville, MD.
3. Ebinuma, H., K. Sugita, E. Matsunaga, and M. Yamakado. 1997. Selection of marker-free transgenic plants using the isopentenyl transferase gene. Proc. Natl. Acad. Sci. 94:2117-2121.
4. European Commissions Scientific Committee for Food. 1996. Opinion on the potential for adverse health effects from the consumption of genetically modified maize. ECSCF, Brussels, Belgium.
5. Ewen, S.W.B., and A. Puzstai. 1999. Effects of diets containing genetically modified potatoes expressing Galanthus nivalis lectin on rat small intestine. The Lancet 354:1353-1354.
6. Flavell, R.B., E. Dart, R.L. Fuchs, and R.T. Fraley. 1992. Selectable marker genes: Safe for plants? Bio/Technology 10:141-144.
7. Goto, F., T. Yoshihara, N. Shigemoto, T. Seiichi, and F. Takaiwa. 1999. Iron fortification of rice seed by the soybean ferritin gene. Nature Biotech. 17:282-286.
8. Haldrup, A., S.G. Petersen, and F.T. Okkels. 1998. The xylose isomerase gene from Thermoanaerobacterium thermosulfurogenes allows effective selection of transgenic plant cells using D-xylose as the selection agent. Plant Mol. Biol. 37:287-296.
9. Hefle, S.L., J.A. Nordlee, and S.L. Taylor. 1996. Allergenic foods. Critical Rev. Food Sci. Nutr. 36:S69-S89.
10. James, C. 1999. Global review of commercialized transgenic crops: 1999. ISAAA Briefs 12: Preveiw. ISAAA, Ithaca, NY.
11. Kaeppler, H.F., G.K. Menon, R.W. Skadsen, A.M. Nuutila, and A.R. Carlson. 2000. Genetic engineering of oat via visual selection of cells expressing green fluorescent protein. Plant Cell Rep. (in press).
12. Karenlampi, S. 1996. Health effects of marker genes in genetically engineered food plants. Nordic Council of Ministers, Copenhagen, Denmark.
13. Kessler, D.A., M.R. Taylor, J.H. Maryanski, E.L. Flamm, and L.S. Kahl. 1992. The safety of foods developed by biotechnology. Science (Washington, DC) 256:1747-1749, 1832.
14. Kuiper, H.A., H.P.J.M. Noteborn, and A.A.C.M. Peijnenburg. 1999. Adequacy of methods for testing the safety of genetically modified foods. The Lancet 354:1315-1316.
15. Lappé, M.A., E.B. Bailey, C. Childress, and K.D.R. Setcheil. 1998. Alterations in clinically important phytoestrogens in genetically modified, herbicide-tolerant soybeans. J. Med. Food 1:241-245.
16. Lehrer, S.B., W.E. Homer, and G. Reese. 1996. Why are some proteins allergenic? Implications for biotechnology. Critical Rev. Food Sci. Nutr. 36:553-564.
17. Metcalfe, D.D., J.D. Astwood, R. Townsend, H.A. Sampson, S.L. Taylor, and R. Fuchs, 1996. Assessment of the allergenic potential of foods derived from genetically engineered crop plants. Crit. Rev. Food Sci. Nutr. 36:8165-8186.
18. Munkvold, G.P., R.L. Hellmich, and L.G. Rice. 1999. Comparison of fumonsin concentrations in kernels of transgenic Bt maize hybrids and nontransgenic hybrids. Plant Dis. 83:130-138.
19. Nordlee, J.A., S.L. Taylor, J.A. Townsend, L.A. Thomas, and R.K. Bush. 1996. Identification of a Brazil-nut allergen in transgenic soybeans. N. Engl. J. Med. 334:688-692.
20. Salyers, A. 1996. The real threat from antibiotics. Nature (London) 384:304-304.
21. Sutcliffe, J.G. 1978. Nucleotide sequence of the ampicillin resistance gene of Escherichia coli plasmid pBR322. Proc. Natl. Acad. Sci. USA 75:3737-3741.
22. Taylor, S.L., and S.B. Lehrer. 1996. Principles and characteristics of food allergens. Crit. Rev. Food Sci. Nutr. 36:S91-S118.
23. U.S. Environmental Protection Agency. 1994. Neomycin phosphotransferase: II. Tolerance exemption. Fed. Regist. 56:4935.
24. U.S. Food and Drug Administration. 1992. Policy statement: Foods derived from new plant varieties. Fed. Regist. 57:22984-23005.
25. U.S. Food and Drug Administration. 1994. Conference on scientific issues related to potential allergenicity in transgenic food crops. FDA Docket no. 94N-0053, document TR-1. FDA, Rockville, MD.
26. U.S. Food and Drug Administration. 1998. Guidance for industry: Use of antibiotic resistance marker genes in transgenic plants. Draft for public comment. http://vm.cfsan.fda.gov/~lrd/biotechm.html (verified 24 Apr. 2000).
27. World Health Organisation. 1993. Health aspects of marker genes in genetically modified plants. Rep. of a WHO workshop. Geneva, Switzerland. WHO, Geneva, Switzerland.
28. World Health Organization. 1996. Biotechnology and food safety. Rep. of a joint FAO/WHO expert consultation. Rome, Italy. WHO, Geneva, Switzerland.
29. Ye, X., S. Al-Babili, A. Kloti, J. Zhang, P. Lucca, P. Beyer, and I. Potrykus. 2000. Engineering the provitamin A pathway into (carotenoid-free) rice endosperm. Science (Washington, DC) 287: 303-305.