Simultaneous determination of the lactone and carboxylate forms of 7- ethyl-10-hydroxycamptothecin (SN-38), the active metabolite of irinotecan (CPT-11), in rat plasma by high performance liquid chromatography

Biological and Pharmaceutical Bulletin

Volumn 20, Issue 7, 1997, Pages 815-819

  Kaneda, Norimasa ^a   Hosokawa, Yukiko ^a   Yokokura, Teruo ^a  

^a YAKULT CENTRAL INSTITUTE FOR MICROBIOLOGICAL RESEARCH   (Japan)

Author keywords

7 ethy 10 hydroxycamptothecin (SN 38); Carboxylate; Irinotecan (CPT 11); Lactone; Simultaneous determination

Indexed keywords

7 ETHYL 10 HYDROXYCAMPTOTHECIN; ANTINEOPLASTIC AGENT; CARBOXYLIC ACID DERIVATIVE; DRUG METABOLITE; IRINOTECAN; LACTONE DERIVATIVE;

ACCURACY; ARTICLE; BLOOD ANALYSIS; CALIBRATION; DRUG DETERMINATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN; RAT;

EID: 0030741008     PISSN: 09186158     EISSN: None     Source Type: Journal    
DOI: 10.1248/bpb.20.815     Document Type: Article

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