IFN-γ induces apoptosis in mouse embryonic stem cells, a putative mechanism of its embryotoxicity

Development Growth and Differentiation

Volumn 42, Issue 3, 2000, Pages 257-264

  Zou, Gang Ming ^a,b   Reznikoff Etievant, Marie Françoise ^a   Hirsch, François ^c   Milliez, Jacques ^a  

^a HÔPITAL SAINT ANTOINE   (France)

^b INSTITUT JACQUES MONOD   (France)

^c CNRS   (France)

Author keywords

Apoptosis; Bcl 2; Embryonic stem cells; IFN

Indexed keywords

DNA; FAS ANTIGEN; GAMMA INTERFERON; LIPOCORTIN 5; PROTEIN BCL 2; TRYPAN BLUE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL GROWTH; CONTROLLED STUDY; EMBRYO; EMBRYOTOXICITY; FLOW CYTOMETRY; IN VITRO STUDY; MOUSE; NONHUMAN; PROTEIN EXPRESSION; STEM CELL;

ANIMALS; ANNEXIN A5; ANTIGENS, CD95; APOPTOSIS; CELL LINE; CELL SURVIVAL; EMBRYO; FLOW CYTOMETRY; INTERFERON TYPE II; MICE; PROTO-ONCOGENE PROTEINS C-BCL-2; STEM CELLS;

ANIMALIA;

EID: 0033921042     PISSN: 00121592     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-169X.2000.00511.x     Document Type: Article

References (41)

1. Berkowitz, R. S., Hill, J. A., Kurtz, C. B. & Anderson, D. J. 1988. Effects of products of activated leukocytes (lymphokines and monokines) on the growth of malignant trophoblast cells in vitro. Am. J. Obstet. Gynecol. 158, 199-203.
2. Cameo, M., Fontana, V., Cameo, P., Vauthay, L. G., Kaplan, J. & Tesone, M. 1999. Similar embryotoxic effects of sera from infertile patients and exogenous interferon-γ on long-term in vitro development of mouse embryos. Hum. Reprod. 14, 959-963.
3. Cohen-Tannoudji, M., Robine, S., Choulika, A. et al. 1998. I-Scel-induced gene replacement at a natural locus in embryonic stem cells. Mol. Cell. Biol. 18, 1444-1448.
4. Darzynkiewicz, Z., Juan, G., Li, X., Gorczyca, W., Murakami, T. & Tragnos, F. 1997. Cytometry in cell necrobiology: Analysis of apoptosis and accidental cell death (necrosis). Cytometry 27, 1-20.
5. Gluksman, A. 1951. Cell deaths in normal vertebrate ontogeny. Biol. Rev. 26, 59-85.
6. Granville, D. J., Carthy, C. M., Hunt, D. W. C. & McManus, B. M. 1998. Apoptosis: Molecular aspects of cell death and disease. Lab. Invest. 78, 893-913.
7. Haimovici, F., Hill, J. A. & Anderson, D. J. 1991. The effects of soluble products of activated lymphocytes and macrophages on blastocyst implantation events in vitro. Biol. Reprod 44, 69-75.
8. Hill, J. A., Haimovici, F. & Anderson, D. J. 1987. Production of activated lymphocytes and macrophages inhibit mouse embryo development in vitro. J. Immunol. 132, 2250-2254.
9. Hill, J. A., Polgar, K. & Anderson, D. J. 1995. T-helper 1-type immunity to trophoblast in women with recurrent spontaneous abortion. JAMA 273, 1933-1936.
10. Ishii, N., Wanaka, A., Ohno, K. et al. 1996. Location of bcl-2, bax, and bcl-x mRNAs in the development inner ear of the mouse. Brain Res 726, 123-128.
11. Johnson, A. L., Bridgham, J. T., Witty, J. P. & Tilly, J. L. 1997. Expression of bcl-2 and nr-13 in the hen ovarian follicles during development. Biol. Reprod. 57, 1096-1103.
12. Jurisicova, A., Latham, K. E., Casper, L. & Vermuza, S. L. 1998. Expression and regulation of gene associated with cell death during murine preimplantation embryo development. Mol. Reprod. Dev. 51, 243-253.
13. Kircheis, R., Kircheis, L., Oshima, H., Kohchi, G. & Mizuno, D. 1996. Selective lysis of early embryonic stem cell by the alternative pathway of complement: A possible mechanism for programmed cell death in embryogenesis. In Vivo 10, 389-403.
14. Koopman, G., Reutelingsperger, C. P. M., Kuijten, G. A. M., Keehnen, R. M. J., Pais, S. T. & van Oers, M. H. J. 1994. Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis. Blood 84, 1415-1420.
15. d conditional lethal mutation. Mamm. Genome 9, 998-1001.
16. Kroemer, G. 1997. The proto-oncogene Bcl-2 and its role in regulating apoptosis. Nat. Med. 3, 614-620.
17. Lea, R. G., Ai-Sharekh, N., Tulppala, M. & Critchley, H. O. D. 1997. The immunolocation of bcl-2 at the maternal-fetal interface in healthy and failing pregnancy. Hum. Reprod 12, 153-158.
18. Lebrun, D. P., Warnke, R. A. & Cleary, M. L. 1993. Expression of bcl-2 in fetal tissue suggested a role in morphogenesis. Am. J. Pathol. 142, 743-753.
19. Lotem, J. & Sachs, L. 1995. Interferon-γ inhibit apoptosis induced by wild-type p53, cytotoxic anti-cancer agents and viability factor deprivation in myeloid cells. Leukemia 9, 685-692.
20. Matsumoto, K., Schleimer, R. P., Saito, H., Likura, Y. & Bochner, B. S. 1995. Induction of apoptosis in human Eosinophils by anti-Fas antibody treatment in vitro. Blood 86, 1437-1443.
21. Matsumoto, Y., Shinzato, T., Takai, I. et al. 1997. Ipr T cells have lower ability to maintain bcl-2 expression ex vivo. Apoptosis 2, 283-288.
22. Nakayama, N., Fang, I. & Elliott, G. 1998. Natural Killer and B-lymphoid potential in CD34+ cells derived from embryonic stem cells differentiated in the presence of vascular endothelial growth factor. Blood 91, 2283-2295.
23. Novack, D. V. & Korsmeyer, S. J. 1994. bcl-2 protein expression during murine development. Am. J. Pathol. 145, 61-73.
24. Pardo, F. S., Su, M. & Borek, C. 1996. Cyclin-D1 induced apoptosis maintains the integrity of the G1/S checkpoint following ionizing radiation irradiation. Cell. Mol. Genet. 22, 135-144.
25. Pegoraro, L., Palumbo, A., Erikson, J. et al. 1984. A. 14;18 and 8;14 chromosomal translocation in a cell line derived from an acute B-cell leukemia. Proc. Natl Acad. Sci. USA 81, 7166-7170.
26. Pepper, C., Hoy, T. & Bentley, P. 1998. Elevated bcl-2/Bax are a consistent feature of apoptosis resistance in B-cell chronic lymphocytic leukemia and are correlated with in vivo chemo-resistance. Leuk. Lymphoma 28, 355-361.
27. Piacentini, M. & Autuori, F. 1994. Immunohistochemical localization of tissue transglutaminase and Bcl-2 in rat uterine tissues during embryo implantation and post-partum involution. Differentiation 57, 51-61.
28. Reed, J. C. 1997. Double identity for protein of the bcl-2 family [review]. Nature 387, 773-776.
29. Rogers, J. M., Taubeneck, M. W., Daston, G. P. et al. 1995. Zinc deficiency cause apoptosis but not cell cycle alteration in organogenesis-stage rat embryos: Effect of varying duration of deficiency. Teratology 52, 149-159.
30. Rokhlin, O. W., Bishop, G. A., Hostager, B. S. et al. 1997. Fas-mediated apoptosis in human prostatic carcinoma cell lines. Cancer Res. 57, 1758-1768.
31. Spets, H., Georgii-Hemming, P., Siljason, J., Nilsson, K. & Jernberg-Wiklund, H. 1998. Fas/APO1 (CD95)-mediated apoptosis is activated by interferon-γ and interferon-α in interleukin-6 (IL-6)-dependent and IL-6-independent multiple myeloma cell lines. Blood 92, 2914-2923.
32. Tamaru, Y., Miyawaki, T., Iwai, K. et al. 1993. Absence of bcl-2 expression by activated CD45RO+ T lymphocytes in acute infections mononucleosis supporting their susceptibility to programmed cell death. Blood 82, 521-527.
33. Trubiani, O., Bosco, D. & Primio, R. D. 1994. Interferon-γ induced programmed cell death in differential human leukemic B cell lines. Exp. Cell Res. 215, 23-27.
34. Tsujimoto, Y., Cossman, J., Jaffe, E. & Croce, C. M. 1985. Involvement of the bcl-2 gene in human follicular lymphoma. Science 228, 1440-1443.
35. Veis, D. J., Sentman, C. L., Bach, E. A. & Korsmeyer, S. J. 1993. Expression of the bcl-2 protein in murine and human thymocytes and in peripheral T lymphocytes. J. Immunol. 151, 2546-2554.
36. Vilagrasa, X., Mezquita, C. & Mezquita, J. 1997. Differential expression of bcl-2 and bcl-x during chicken spermato-genesis. Mol. Reprod. Dev. 47, 26-29.
37. Wen, L. P., Madani, K., Fahrni, J. A., Duncan, S. R. & Rosen, G. D. 1997. Dexamethasone inhibits lung epithelial cell apoptosis induced by IFN-γ and Fas. Am. J. Physiol. 273 (5Pt 1), L921-929.
38. Xu, X., Fu, X. Y., Plate, J. & Chong, A. S. F. 1998. IFN-γ induces cell growth inhibition by Fas-mediated apoptosis: Required of STAT1 protein for up-regulation of Fas and FasL expression. Cancer Res. 58, 2832-2837.
39. Yanagida, M., Fukamachi, H., Takei, M. et al. 1996 Interferon-gamma promotes the survival and Fc epsilon Rl-mediated histamine release in cultured human mast cells. Immunology 89, 547-552.
40. Zimowska, W., Motyl, T., Skierski, J. et al. 1997. Apoptosis and bcl-2 protein changes in L1210 leukemic cells exposed to oxidative stress. Apoptosis 2, 529-539.
41. Zou, G. M., Reznikoff-Etievant, M. F., Leon, A., Verge, V., Milliez, J. & Hirsch, F. 2000. Fas-mediated apoptosis of mouse embryo stem cells: Its role during embryonic development. Am. J. Reprod. Immunol 43, (in press).