Up-regulation of cell surface insulin receptor by protein kinase C-α in adrenal chromaffin cells: Involvement of transcriptional and translational events

Journal of Neurochemistry

Volumn 75, Issue 2, 2000, Pages 672-682

  Yamamoto, Ryuichi ^a   Kobayashi, Hideyuki ^a   Yanagita, Toshihiko ^a   Yokoo, Hiroki ^a   Kurose, Takeshi ^a   Shiraishi, Seiji ^a   Minami, Shin Ichi ^a   Matsukura, Shigeru ^a   Wada, Akihiko ^a  

^a UNIVERSITY OF MIYAZAKI   (Japan)

Author keywords

125I Insulin binding; Insulin receptor; Northern blot; Protein kinase C ; Up regulation; Western blot

Indexed keywords

INSULIN RECEPTOR; PROTEIN KINASE C ACTIVATOR;

ANIMAL CELL; ARTICLE; CELL SURFACE; CHROMAFFIN CELL; HORMONE RECEPTOR INTERACTION; INTRACELLULAR TRANSPORT; NONHUMAN; PRIORITY JOURNAL; RNA SYNTHESIS;

ADRENAL MEDULLA; ANIMALS; CARBAZOLES; CATTLE; CELL MEMBRANE; CELLS, CULTURED; CHROMAFFIN CELLS; ENZYME INHIBITORS; INDOLES; INSULIN; ISOENZYMES; KINETICS; PHORBOL 12,13-DIBUTYRATE; PHORBOL ESTERS; PROTEIN BIOSYNTHESIS; PROTEIN KINASE C; PROTEIN KINASE C-ALPHA; RECEPTOR, INSULIN; TRANSCRIPTION, GENETIC; UP-REGULATION;

ANIMALIA; BOVINAE;

EID: 0033914653     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2000.0750672.x     Document Type: Article

References (80)

1. Almholt K., Arkhammar P. O. G., Thastrup O., and Tullin S. (1999) Simultaneous visualization of the translocation of protein kinase Cα-green fluorescent protein hybrids and intracellular calcium concentrations. Biochem. J. 337, 211-218.
2. Bass J., Kurose T., Pashmforoush M., and Steiner D. F. (1996) Fusion of insulin receptor ectodomains to immunoglobulin constant domains reproduces high-affinity insulin binding in vitro. J. Biol. Chem. 271, 19367-19375.
3. Berti L., Mosthaf L., Kroder G., Kellerer M., Tippmer S., Mushack J., Seffer E., Seedorf K., and Haring H. (1994) Glucose-induced translocation of protein kinase C isoforms in rat-1 fibroblasts is paralleled by inhibition of the insulin receptor tyrosine kinase. J. Biol. Chem. 269, 3381-3386.
4. Bevan A. P., Krook A., Tikerpae J., Seabright P. J., Siddle K., and Smith G. D. (1997) Chloroquine extends the lifetime of the activated insulin receptor complex in endosomes. J. Biol. Chem. 272, 26833-26840.
5. Bortoli S., Amessou M., Collinet M., Desbuquois B., and Lopez S. (1997) Vanadate, but not insulin, inhibits insulin receptor gene expression in rat hepatoma cells. Endocrinology 138, 4821-4829.
6. Bottaro D. P., Bonner-Weir S., and King G. L. (1989) Insulin receptor recycling in vascular endothelial cells. Regulation by insulin and phorbol ester. J. Biol. Chem. 264, 5916-5923.
7. Briata P., Briata L., and Gherzi R. (1990) Glucose starvation and glycosylation inhibitors reduce insulin receptor gene expression: characterization and potential mechanism in human cells. Biochem. Biophys. Res. Commun. 169, 397-405.
8. Brunetti A., Brunetti L., Foti D., Accili D., and Goldfine I. D. (1996) Human diabetes associated with defects in nuclear regulatory proteins for the insulin receptor gene. J. Clin. Invest. 97, 258-262.
9. Buccione R., Bannykh S., Santone I., Baldassarre M., Facchiano F., Bozzi Y., Di Tullio G., Mironov A., Luini A., and De Matteis M. A. (1996) Regulation of constitutive exocytic transport by membrane receptors. A biochemical and morphometric study. J. Biol. Chem. 271, 3523-3533.
10. Cavenagh M. M., Whitney J. A., Carroll K., Zhang C.-J., Boman A. L., Rosenwald A. G., Mellman I., and Kahn R. A. (1996) Intracellular distribution of Arf proteins in mammalian cells. Arf6 is uniquely localized to the plasma membrane. J. Biol. Chem. 271, 21767-21774.
11. Chakrabarti R., Buxton J., Joly M., and Corvera S. (1994) Insulin-sensitive association of GLUT-4 with endocytic clathrin-coated vesicles revealed with the use of brefeldin A. J. Biol. Chem. 269, 7926-7933.
12. Cheatham B. and Kahn C. R. (1995) Insulin action and the insulin signaling network. Endocr. Rev. 16, 117-142.
13. Chijiwa T., Mishima A., Hagiwara M., Sano M., Hayashi K., Inoue T., Naito K., Toshioka T., and Hidaka H. (1990) Inhibition of forskolin-induced neurite outgrowth and protein phosphorylation by a newly synthesized selective inhibitor of cyclic AMP-dependent protein kinase, N[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide (H-89), of PC12D pheochromocytoma cells. J. Biol. Chem. 265, 5267-5272.
14. Chin J. E., Dickens M., Tavare J. M., and Roth R. A. (1993) Overexpression of protein kinase C isoenzymes α, β1, γ, and ε in cells overexpressing the insulin receptor. Effects on receptor phosphorylation and signaling. J. Biol. Chem. 268, 6338-6347.
15. Considine R. V., Nyce M. R., Allen L. E., Morales L. M., Triester S., Serrano J., Colberg J., Lanza-Jacoby S., and Caro J. F. (1995) Protein kinase C is increased in the liver of humans and rats with non-insulin-dependent diabetes mellitus: an alteration not due to hyperglycemia. J. Clin. Invest. 95, 2938-2944.
16. Craviso G. L., Hemelt V. B., and Waymire J. C. (1995) The transient nicotinic stimulation of tyrosine hydroxylase gene transcription in bovine adrenal chromaffin cells is independent of c-fos gene activation. Mol. Brain Res. 29, 233-244.
17. Dahmer M. K. and Perlman R. L. (1988) Bovine chromaffin cells have insulin-like growth factor-I (IGF-I) receptors: IGF-I enhances catecholamine secretion. J. Neurochem. 51, 321-323.
18. Danielsen A., Larsen E., and Gammeltoft S. (1990) Chromaffin cells express two types of insulin-like growth factor receptors. Brain Res. 518, 95-100.
19. Danielsen A. G., Liu F., Hosomi Y., Shii K., and Roth R. A. (1995) Activation of protein kinase C α inhibits signaling by members of the insulin receptor family. J. Biol. Chem. 270, 21600-21605.
20. Davidson M. B. and Kaplan S. A. (1977) Increased insulin binding by hepatic plasma membranes from diabetic rats. J. Clin. Invest. 59, 22-30.
21. De Matteis M. A., Santini G., Kahn R. A., Di Tullio G., and Luini A. (1993) Receptor and protein kinase C-mediated regulation of ARF binding to the Golgi complex. Nature 364, 818-821.
22. de Pablo F. and de la Rosa E. J. (1995) The developing CNS: a scenario for the action of proinsulin, insulin and insulin-like growth factors. Trends Neurosci. 18, 143-150.
23. Dikic I., Schlessinger J., and Lax I. (1994) PC12 cells overexpressing the insulin receptor undergo insulin-dependent neuronal differentiation. Curr. Biol. 4, 702-708.
24. Fladeby C., Bjønness B., and Serck-Hanssen G. (1996) GLUT1-mediated glucose transport and its regulation by IGF-I in cultured bovine chromaffin cells. J. Cell. Physiol. 169, 242-247.
25. Formisano P., Oriente F., Miele C., Caruso M., Auricchio R., Vigliotta G., Condorelli G., and Beguinot F. (1998) In NIH-3T3 fibroblasts, insulin receptor interaction with specific protein kinase C isoforms controls receptor intracellular routing. J. Biol. Chem. 273, 13197-13202.
26. Frölich L., Blum-Degen D., Bernstein H.-G., Engelsberger S., Humrich J., Laufer S., Muschner D., Thalheimer A., Türk A., Hoyer S., Zöchling R., Boissl K. W., Jellinger K., and Riederer P. (1998) Brain insulin and insulin receptors in aging and sporadic Alzheimer's disease. J. Neural Transm. 105, 423-438.
27. Gewolb I. H., O'Brien J., Palese T. A., and Phillip M. (1994) High glucose and insulin decrease fetal lung insulin receptor mRNA and tyrosine kinase activity in vitro. Biochem. Biophys. Res. Commun. 202, 694-700.
28. Giasson E. and Meloche S. (1995) Role of p70 S6 protein kinase in angiotensin II-induced protein synthesis in vascular smooth muscle cells. J. Biol. Chem. 270, 5225-5231.
29. Harris T. E., Persaud S. J., and Jones P. M. (1996) Atypical isoforms of PKC and insulin secretion from pancreatic β-cells: evidence using G̈6976 and Ro 31-8220 as PKC inhibitors. Biochem. Biophys. Res. Commun. 227, 672-676.
30. Hatada E. N., McClain D. A., Potter E., Ullrich A., and Olefsky J. M. (1989) Effects of growth and insulin treatment on the levels of insulin receptors and their mRNA in Hep G2 cells. J. Biol. Chem. 264, 6741-6747.
31. Hauguel-de-Mouzon S., Mrejen C., Alengrin F., and Van Obberghen E. (1995) Glucose-induced stimulation of human insulin-receptor mRNA and tyrosine kinase activity in cultured cells. Biochem. J. 305, 119-124.
32. Hickinson D. M., Lucocq J. M., Towler M. C., Clough S., James J., James S. R., Downes C. P., and Ponnambalam S. (1997) Association of a phosphatidylinositol-specific 3-kinase with a human trans-Golgi network resident protein. Curr. Biol. 7, 987-990.
33. 1B-adrenoceptor. Br. J. Pharmacol. 124, 55-62.
34. Holz R. W., Bittner M. A., Peppers S. C., Senter R. A., and Eberhard D. A. (1989) MgATP-independent and MgATP-dependent exocytosis. Evidence that MgATP primes adrenal chromaffin cells to undergo exocytosis. J. Biol. Chem. 264, 5412-5419.
35. Hwang J. B. and Frost S. C. (1999) Effect of alternative glycosylation on insulin receptor processing. J. Biol. Chem. 274, 22813-22820.
36. Inoguchi T., Xia P., Kunisaki M., Higashi S., Feener E. P., and King G. L. (1994) Insulin's effect on protein kinase C and diacylglycerol induced by diabetes and glucose in vascular tissues. Am. J. Physiol. 267, E369-E379.
37. Jones S. M. 61nd Howell K. E. (1997) Phosphatidylinositol 3-kinase is required for the formation of constitutive transport vesicles from the TGN. J. Cell Biol. 139, 339-349.
38. Kadowaki T., Kasuga M., Akanuma Y., Ezaki O., and Takaku F. (1984) Decreased autophosphorylation of the insulin receptor-kinase in streptozotocin-diabetic rats. J. Biol. Chem. 259, 14208-14216.
39. Knutson V. P. (1991) Cellular trafficking and processing of the insulin receptor. FASEB J. 5, 2130-2138.
40. Kobayashi M. and Olefsky J. M. (1979) Effects of streptozotocin-induced diabetes on insulin binding, glucose transport, and intracellular glucose metabolism in isolated rat adipocytes. Diabetes 28, 87-95.
41. Laemmli U. K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685.
42. Leal M. A., Aller P., Mas A., and Calle C. (1995) The effect of 1,25-dihydroxyvitamin D3 on insulin binding, insulin receptor mRNA levels, and isotype RNA pattern in U-937 human promonocytic cells. Exp. Cell Res. 217, 189-194.
43. Lee J. K., Tam J. W., Tsai M. J., and Tsai S. Y. (1992) Identification of cis-and trans-acting factors regulating the expression of the human insulin receptor gene. J. Biol. Chem. 267, 4638-4645.
44. Levy J. R. and Hug V. (1992) Regulation of insulin receptor gene expression. Cell cycle-mediated effects on insulin receptor mRNA stability. J. Biol. Chem. 267, 25289-25295.
45. Llosas M. D., Batlle E., Coll O., Skoudy A., Fabre M., and Garcia de Herreros A. (1996) Evidence for a role of conventional protein kinase-C α in the control of homotypic contacts and cell scattering of HT-29 human intestinal cells. Biochem. J. 315, 1049-1054.
46. Marshall C. J. (1995) Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Cell 80, 179-185.
47. Martiny-Baron G., Kazanietz M. G., Mischak H., Blumberg P. M., Kochs G., Hug H., Marme D., and Schachtele C. (1993) Selective inhibition of protein kinase C isozymes by the indolocarbazole Gö6976. J. Biol. Chem. 268, 9194-9197.
48. Mizukami Y., Hirata T., and Yoshida K. (1997) Nuclear translocation of PKC ζ during ischemia and its inhibition by wortmannin, an inhibitor of phosphatidylinositol 3-kinase. FEBS Lett. 401, 247-251.
49. Mochly-Rosen D. and Gordon A. S. (1998) Anchoring proteins for protein kinase C: a means for isozyme selectivity. FASEB J. 12, 35-42.
50. Morinaga N., Moss J., and Vaughan M. (1997) Cloning and expression of a cDNA encoding a bovine brain brefeldin A-sensitive guanine nucleotide-exchange protein for ADP-ribosylation factor. Proc. Natl. Acad. Sci. USA 94, 12926-12931.
51. Moss J. and Vaughan M. (1995) Structure and function of ARF proteins: activators of cholera toxin and critical components of intracellular vesicular transport processes. J. Biol. Chem. 270, 12327-12330.
52. Newton A. C. (1997) Regulation of protein kinase C. Curr. Opin. Cell Biol. 9, 161-167.
53. Proud C. G. (1996) p70 S6 kinase: an enigma with variations. Trends Biochem. Sci. 21, 181-185.
54. Rohilla A. M., Anderson C., Wood W. M., and Berhanu P. (1991) Insulin downregulates the steady-state level of its receptor's messenger ribonucleic acid. Biochem. Biophys. Res. Commun. 175, 520-526.
55. Rosenzweig S. A., Zetterstrom C., and Benjamin A. (1990) Identification of retinal insulin receptors using site-specific antibodies to a carboxyl-terminal peptide of the human insulin receptor α-subunit. Up-regulation of neuronal insulin receptors in diabetes. J. Biol. Chem. 265, 18030-18034.
56. Ross J. (1995) mRNA stability in mammalian cells. Microbiol. Rev. 59, 423-450.
57. 1, γ, δ and ε by phorbol esters of different biological activities. FEBS Lett. 288, 5-9.
58. Saad M. J., Folli F., Araki E., Hashimoto N., Csermely P., and Kahn C. R. (1994) Regulation of insulin receptor, insulin receptor substrate-1 and phosphatidylinositol 3-kinase in 3T3-F442A adipocytes. Effects of differentiation, insulin, and dexamethasone. Mol. Endocrinol. 8, 545-557.
59. Schmalz D., Kalkbrenner F., Hucho F., and Buchner K. (1996) Transport of protein kinase C α into the nucleus requires intact cytoskeleton while the transport of a protein containing a canonical nuclear localization signal does not. J. Cell Sci. 109, 2401-2406.
60. Schmalz D., Hucho F., and Buchner K. (1998) Nuclear import of protein kinase C occurs by a mechanism distinct from the mechanism used by protein with a classical nuclear localization signal. J. Cell Sci. 111, 1823-1830.
61. Schonhorn J. E. and Wessling-Resnick M. (1994) Brefeldin A down-regulates the transferrin receptors in K562 cells. Mol. Cell. Biochem. 135, 159-169.
62. Schubert C., Carel K., DePaolo D., Leitner W., and Draznin B. (1996) Interactions of protein kinase C with insulin signaling. Influence on GAP and Sos activities. J. Biol. Chem. 271, 15311-15314.
63. Seaman M. N., Burd C. G., and Emr S. D. (1996) Receptor signalling and the regulation of endocytic membrane transport. Curr. Opin. Cell Biol. 8, 549-556.
64. Seedorf K., Shearman M., and Ullrich A. (1995) Rapid and long-term effects on protein kinase C on receptor tyrosine kinase phosphorylation and degradation. J. Biol. Chem. 270, 18953-18960.
65. Sena C. M., Rosário L. M., Parker P. J., Patel V., and Boarder M. R. (1996) Differential regulation of histamine-and bradykinin-stimulated phospholipase C in adrenal chromaffin cells: evidence for involvement of different protein kinase C isoforms. J. Neurochem. 66, 1086-1094.
66. Srinivasan M. and Begum N. (1994) Stimulation of protein phosphatase-1 activity by phorbol esters. Evaluation of the regulatory role of protein kinase C in insulin action. J. Biol. Chem. 269, 16662-16667.
67. + channel (ENaC) by ubiquitination. EMBO J. 16, 6325-6336.
68. Terzian A. R., Zhang X., and Rubin R. P. (1996) Differential modulation of protein kinase C isozymes in rat parotid acinar cells. Biochem. Pharmacol. 52, 569-577.
69. Tewari D. S., Cook D. M., and Taub R. (1989) Characterization of the promoter regions and 3′ end of the human insulin receptor gene. J. Biol. Chem. 264, 16238-16245.
70. Toledo-Aral J. J., Brehm P., Halegoua S., and Mandel G. (1995) A single pulse of nerve growth factor triggers long-term neuronal excitability through sodium channel gene induction. Neuron 14, 607-611.
71. Tuominen R. K., Hudson P. M., McMillian M. K., Ye H., Stachowiak M. K., and Hong J.-S. (1991) Long-term activation of protein kinase C by angiotensin II in cultured bovine adrenal medullary cells. J. Neurochem. 56, 1292-1298.
72. Tuominen R. K., McMillian M. K., Ye H., Stachowiak M. K., Hudson P. M., and Hong J.-S. (1992) Long-term activation of protein kinase C by nicotine in bovine adrenal chromaffin cells. J. Neurochem. 58, 1652-1658.
73. Vanhaesebroeck B., Leevers S. J., Panayotou G., and Waterfield M. D. (1997) Phosphoinositide 3-kinases: a conserved family of signal transducers. Trends Biochem. Sci. 22, 267-272.
74. Westermann P., Knoblich M., Maier O., Lindschau C., and Haller H. (1996) Protein kinase C bound to the Golgi apparatus supports the formation of constitutive transport vesicles. Biochem. J. 320, 651-658.
75. Wilson S. P., Viveros O. H., and Kirshner N. (1985) Relationship between the regulation of enkephalin-containing peptide and dopamine-β-hydroxylase levels in cultured adrenal chromaffin cells. J. Neurochem. 45, 1363-1370.
76. Yamamoto R., Yanagita T., Kobayashi H., Yuhi T., Yokoo H., and Wada A. (1996) Up-regulation of functional voltage-dependent sodium channels by insulin in cultured bovine adrenal chromaffin cells. J. Neurochem. 67, 1401-1408.
77. Yanagita T., Wada A., Yamamoto R., Kobayashi H., Yuhi T., Urabe M., and Niina H. (1996) Protein kinase C-mediated down-regulation of voltage-dependent sodium channels in adrenal chromaffin cells. J. Neurochem. 66, 1249-1253.
78. 1-subunit mRNA levels in adrenal chromaffin cells. J. Neurochem. 73, 1749-1757.
79. Yanagita T., Kobayashi H., Yamamoto R., Kataoka H., Yokoo H., Shiraishi S., Minami S., Koono M., and Wada A. (2000) Protein kinase C-α and -ε down-regulate cell surface sodium channels via differential mechanisms in adrenal chromaffin cells. J. Neurochem. 74, 1674-1684.
80. Zetterström C., Benjamin A., and Rosenzweig S. A. (1992) Differential expression of retinal insulin receptors in STZ-induced diabetic rats. Diabetes 41, 818-825.