Soy protein in the management of hyperlipidemia

Annals of Pharmacotherapy

Volumn 34, Issue 7-8, 2000, Pages 931-935

  Costa, Rebecca L ^a   Summa, Maria A ^b  

^a DURHAM VA MEDICAL CENTER   (United States)

^b MASSACHUSETTS COLLEGE OF PHARMACY AND HEALTH SCIENCES   (United States)

Author keywords

Cholesterol; High density lipoprotein; Isoflavone; Low density lipoprotein; Soy

Indexed keywords

CHOLESTEROL; LIPID; SOYBEAN PROTEIN;

ARTICLE; CHOLESTEROL BLOOD LEVEL; DIETARY INTAKE; HUMAN; HYPERLIPIDEMIA; LIPID BLOOD LEVEL; PRIORITY JOURNAL; PROTEIN INTAKE; SOYBEAN;

EID: 0033913746     PISSN: 10600280     EISSN: None     Source Type: Journal    
DOI: 10.1345/aph.19371     Document Type: Article

References (22)

1. Murkies AL, Wilcox G, Davis SR. Clinical review 92: phytoestrogens. J Clin Endocrinol Melab 1998;83:297-303.
2. Kolar CW, Richert SH, Decker CD, Steinke FH, Van Der Zanden RJ. Isolated soy protein. In: Altschul AM, Wicke HL, eds. New protein foods. Vol 5. New York: Academic Press, 1985:260-99.
3. Murkies A, Lombard C, Strauss BJG, Wilcox G, Burgher HG, Morton MS. Dietary flour supplementation decreases post-menopausal hot flushes: effect of soy and wheat. Maturitas 1995;21:189-95.
4. Albertazzi P, Pansini F, Bonaccorsi G, Zanotti L, Forini E. De Aloysio D. The effect of dietary soy supplementation on hot flushes. Obstet Gynecol 1998;91:6-11.
5. Cassidy A, Bingham S, Setchell KDR. Biological effects of a diet rich in isoflavones on the menstrual cycle of premenopausal women. Am J Clin Nutr 1994;60:333-40.
6. Peterson G, Barnes S. Genistein inhibition of the growth of human breast cancer cells: independence from estrogen receptors and multi-drug resistance gene. Biochem Biophys Res Commun 1991;179:661-7.
7. Potter SM, Baum J, Teng H, Stillman RJ, Shay NF, Erdman JW. Soy protein and isoflavones: their effects on blood lipids and bone density in post menopausal women. Am J Clin Nutr 1998;68(suppl):1375s-9s.
8. Miksicek RJ. Interaction of naturally occurring nonsteroidal estrogens with expressed recombinant human estrogen receptor. J Steroid Biochem Molec Biol 1994;49:153-60.
9. Walsh BW, Schiff I, Rosner B, Greenberg L, Ravnikar B, Sacks FM. Effects of postmenopausal estrogen replacement on the concentrations and metabolism of plasma lipoproteins. N Engl J Med 1991;325:1196-204.
10. Rijpkema AH, Van der Sanden AA, Ruijs AH. Effects of post-menopausal oestrogen-progesten replacement therapy on serum lipids and lipoproteins: a review. Maturitas 1990;12:259-85.
11. Lobo RA. Clinical review 27: effects of hormone replacement on lipids and lipoproteins in post-menopausal women. J Clin Endocrinol Metab 1991;73:925-30.
12. Anthony MS, Clarkson TB, Williams JK. Effects of soy isoflavones on atherosclerosis: potential mechanisms. Am J Clin Nutr 1998;68(suppl):1390s-3s.
13. Lichenstein AH. Soy protein, isoflavones and cardiovascular disease risk. J Nutr 1998;128:1589-92.
14. Anthony MS, Clarkson TB, Hughes CL Jr, Morgan TM, Burke GL. Soybean isoflavones improve cardiovascular risk factors without affecting the reproductive system of peripubertal rhesus monkeys. J Nutr 1996; 126:43-50.
15. Nagata C, Takatsuka N, Kurisu Y, Shimizu H. Decreased serum total cholesterol concentration is associated with high intake of soy products in Japanese men and women. J Nutr 1998;128:209-13.
16. Wong WW, Smith EO, Stuff JE, Hachey DL, Heird WC, Pownell HJ. Cholesterol-lowering effect of soy protein in normocholesterolemic and hypercholesterolemic men. Am J Clin Nutr 1998;68(suppl):1385s-9s.
17. Nilausen K, Meinertz H. Variable lipemic response to dietary soy protein in healthy, normolipemic men. Am J Clin Nutr 1998;68(suppl):1380s-4s.
18. Tikkanen MJ, Wahala K, Ojala S, Vihma V, Adlercreutz H. Effect of soybean phytoestrogen intake on low density lipoprotein oxidation resistance. Proc Natl Acad Sci USA 1998;95:3106-10.
19. Baum J, Teng H, Erdman JW, Weigel RM, Klein BP, Persky VW, et al. Long-term intake of soy protein improves blood lipid profiles and increases mononuclear cell low-density-lipoprotein receptor messenger RNA in hypercholesterolemic, postmenopausal women. Am J Clin Nutr 1998;68:545-51.
20. Washburn S, Burke GL, Morgan T, Anthony M. Effect of soy protein supplementation of serum lipoproteins, blood pressure, and menopausal symptoms in perimenopausal women. Menopause 1999;6:7-13.
21. Anderson JW, Johnstone BM, Cook-Newell ME. Meta-analysis of the effects of soy protein intake on serum lipids. N Engl J Med 1995;333: 276-82.
22. Denke MA. Cholesterol-lowering diets: a review of the evidence. Arch Intern Med 1995;155:17-26.