Exploiting excess sharing: A more powerful test of linkage for affected sib pairs than the transmission/disequilibrium test

American Journal of Human Genetics

Volumn 66, Issue 6, 2000, Pages 2005-2008

  Wicks, Jacqueline ^a,b  

^a AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

^b UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ALLELE; ARTICLE; FAMILY STUDY; GENE LINKAGE DISEQUILIBRIUM; MATHEMATICAL ANALYSIS; PEDIGREE; PRIORITY JOURNAL;

EID: 0033911953     PISSN: 00029297     EISSN: None     Source Type: Journal    
DOI: 10.1086/302912     Document Type: Article

References (4)

1. Martin ER, Kaplan NL, Weir BS (1997) Tests for linkage and association in nuclear families. Am J Hum Genet 61: 439-448
2. McGinnis RE (1998) Hidden linkage: a comparison of the affected sib pair (ASP) test and transmission/disequilibrium test (TDT). Ann Hum Genet 62:159-179
3. Spielman RS, Ewens WJ (1996) The TDT and other family-based tests for linkage disequilibrium and association. Am J Hum Genet 59:983-989
4. Spielman RS, McGinnis RE, Ewens WJ (1993) Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM). Am J Hum Genet 52:506-516