Two amino acids in glutamic acid decarboxylase act in concert for maintenance of conformational determinants recognised by Type I diabetic autoantibodies

Diabetologia

Volumn 43, Issue 7, 2000, Pages 881-889

  Tree, T I M ^a   Morgenthaler, N G ^a   Duhindan, N ^a   Hicks, K E ^a   Madec, A M ^b   Scherbaum, W A ^c   Banga, J P ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b INSERM   (France)

^c HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

Autoimmune polyendocrine syndrome; Glutamic acid decarboxylase 65; Human monoclonal antibodies; Mutants; Stiff man syndrome

Indexed keywords

AUTOANTIBODY; AUTOANTIGEN; GLUTAMATE DECARBOXYLASE; IMMUNOGLOBULIN G ANTIBODY;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANTIGEN BINDING; ARTICLE; CONTROLLED STUDY; ENZYME ANALYSIS; HUMAN; HUMAN CELL; INSULIN DEPENDENT DIABETES MELLITUS; MULTIPLE ENDOCRINE ADENOMATOSIS; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SITE DIRECTED MUTAGENESIS; STIFF MAN SYNDROME;

EID: 0033911363     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001250051465     Document Type: Article

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