Effects of hyperglycaemia and hyperinsulinaemia on proximal gastric motor and sensory function in humans

Clinical Science

Volumn 99, Issue 1, 2000, Pages 37-46

  Van Petersen, A S ^a   Vu, M K ^a   Lam, W F ^a   Lamers, C B H W ^a   Ringers, J ^a   Masclee, A A M ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Gastric barostat; Gastric compliance; Gastric fundus; Postprandial gastric relaxation

Indexed keywords

GLUCOSE; INSULIN;

ADULT; ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN EXPERIMENT; HYPERGLYCEMIA; HYPERINSULINEMIA; MALE; NORMAL HUMAN; POSTPRANDIAL STATE; PRESSURE; PRIORITY JOURNAL; SENSORY NERVE; STOMACH DISTENSION; STOMACH FUNCTION; STOMACH MOTILITY;

EID: 0033910756     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/cs0990037     Document Type: Article

References (35)

1. 1 Horowitz, M. and Fraser, R. (1994) Disordered gastric motor function in diabetes mellitus. Diabetologia, 37, 543-551
2. 2 Samsom, M., Roelofs, J. M., Akkermans, L. M., vanBerge-Henegouwen, G. P. and Smout, A. J. (1998) Proximal gastric motor activity in response to a liquid meal in type I diabetes mellitus with autonomic neuropathy. Dig. Dis. Sci. 43, 491-496
3. 3 Samsom, M., Salet, G. A., Roelofs, J. M., Akkermans, L. M., vanBerge-Henegouwen, G. P. and Smout, A. J. (1995) Compliance of the proximal stomach and dyspeptic symptoms in patients with type I diabetes mellitus. Dig. Dis. Sci. 40, 2037-2042
4. 4 Barnett, J. L. and Owyang, C. (1988) Serum glucose concentration as a modulator of interdigestive gastric motility. Gastroenterology, 94, 739-744
5. 5 Fraser, R. J., Horowitz, M., Maddox, A. F., Harding, P. E., Chatterton, B. E. and Dent, J. (1990) Hyperglycaemia slows gastric emptying in type 1 (insulin-dependent) diabetes mellitus. Diabetologia, 33, 675-680
6. 6 Hebbard, G. S., Samsom, M., Sun, W. M., Dent, J. and Horowitz, M. (1996) Hyperglycemia affects proximal gastric motor and sensory function during small intestinal triglyceride infusion. Am. J. Physiol. 271, G814-G819
7. 7 Hebbard, G. S., Sun, W. M., Dent, J. and Horowitz, M. (1996) Hyperglycaemia affects proximal gastric motor and sensory function in normal subjects. Eur. J. Gastroenterol. Hepatol. 8, 211-217
8. 8 Schvarez, E., Palmer, M., Aman, J., Horowitz, M., Stridsberg, M. and Berne, C. (1997) Physiological hyperglycemia slows gastric emptying in normal subjects and patients with insulin-dependent diabetes mellitus. Gastroenterology 113, 60-66
9. 9 Kong, M. F., King, P., Macdonald, I. A. et al. (1998) Effect of euglycaemic hyperinsulinaemia on gastric emptying and gastrointestinal hormone responses in normal subjects. Diabetologia 41, 474-481
10. 10 Gielkens, H. A., Verkijk, M., Frolich, M., Lamers, C. B. and Masclee, A. A. (1997) Is the effect of acute hyperglycaemia on interdigestive antroduodenal motility and small-bowel transit mediated by insulin? Eur. J. Clin. Invest. 27, 703-710
11. 11 Hasler, W. L., Soudah, H. C., Dulai, G. and Owyang, C. (1995) Mediation of hyperglycemia-evoked gastric slow-wave dysrhythmias by endogenous prostaglandins. Gastroenterology 108, 727-736
12. 12 Azpiroz, F. and Malagelada, J. R. (1987) Gastric tone measured by an electronic barostat in health and postsurgical gastroparesis. Gastroenterology 92, 934-943
13. 13 Notivol, R., Coffin, B., Azpiroz, F., Mearin, F., Serra, J. and Malagelada, J. R. (1995) Gastric tone determines the sensitivity of the stomach to distention. Gastroenterology 108, 330-336
14. 14 DeFronzo, R. A., Tobin, J. D. and Andres, R. (1979) Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am. J. Physiol. 237, E214-E223
15. 15 Ward, W. K., Halter, J. B., Beard, J. C. and Porte, D. J. (1984) Adaptation of B and A cell function during prolonged glucose infusion in human subjects. Am. J. Physiol. 246, E405-E411
16. 16 Nijs, H. G., Radder, J. K., Frölich, M. and Krans, H. M. (1990) In vivo relationship between insulin clearance and action in healthy subjects and IDDM patients. Diabetes 39, 333-339
17. 17 Jansen, J. B. and Lamers, C. B. (1983) Radioimmunoassay of cholecystokinin in human tissue and plasma. Clin. Chim. Acta 131, 305-316
18. 18 Lamers, C. B., Diemel, C. M., vanLeer, E., vanLeusen, R. and Peetoom, J. J. (1982) Mechanism of elevated serum pancreatic polypeptide concentrations in chronic renal failure. J. Clin. Endocrinol. Metab. 55, 922-926
19. 19 Jansen, J. B. and Lamers, C. B. (1982) Effect of changes in serum calcium on secretin-stimulated serum gastrin in patients with Zollinger-Ellison syndrome. Gastroenterology 83, 173-178
20. 20 Byrne, M. M., Pluntke, K., Wank, U. et al. (1998) Inhibitory effects of hyperglycaemia on fed jejunal motility: potential role of nypennsulinaemia. Eur. J. Clin. Invest. 28, 72-78
21. 21 Boeckxstaens, G. E., Horowitz, M., Bermingham, H. and Holloway, R. H. (1997) Physiological variations in blood glucose concentration affect oesophageal motility and sensation in normal subjects. Neurogastroenterol. Motil. 9, 239-246
22. 22 Sims, M. A., Hasler, W. L., Chey, W. D., Kim, M. S. and Owyang, C. (1995) Hyperglycemia inhibits mechanoreceptor-mediated gastrocolonic responses and colonic peristaltic reflexes in healthy humans. Gastroenterology 108, 350-359
23. 23 Gielkens, H. A., vanOostayen, J. A., Frolich, M., Biemond, I., Lamers, C. B. and Masclee, A. A. (1998) Dose-dependent inhibition of postprandial gallbladder motility and plasma hormone secretion during acute hyperglycemia. Scand. J. Gastroenterol. 33, 1074-1079
24. 24 Verhagen, M. A., Rayner, C. K., Andrews, J. M. et al. (1998) Physiological changes in blood glucose do not affect gastric compliance and perception in normal subjects. Am. J. Physiol. 276, G761-G766
25. 25 Björnsson, E. S., Urbanavicius, V., Eliasson, B., Attvall, S., Smith, U. and Abrahamsson, H. (1995) Effects of insulin and beta-adrenergic blockade on the migrating motor complex in humans. Scand. J. Gastroenterol. 30, 219-224
26. 26 Kong, M. F., King, P., Macdonald, I. A. et al. (1999) Euglycaemic hyperinsulinaemia does not affect gastric emptying in type I and type II diabetes mellitus. Diabetologia 42, 365-372
27. 27 Azpiroz, F. and Malagelada, J. R. (1986) Vagally mediated gastric relaxation induced by intestinal nutrients in the dog. Am. J. Physiol. 251, G727-G735
28. 28 Schwartz, T. W. (1983) Pancreatic polypeptide: a hormone under vagal control. Gastroenterology 85, 1411-1425
29. 29 Meier, R., Hildebrand, P., Thumshirn, M. et al. (1990) Effect of loxiglumide, a cholecystokinin antagonist, on pancreatic polypeptide release in humans. Gastroenterology 99, 1757-1762
30. 30 Tsuda, K., Seino, Y., Mori, K. et al. (1981) Effect of truncal vagotomy on pancreatic polypeptide response after intravenous glucose administration. Regul. Peptides 1, 347-352
31. 31 Hirano, T. and Niijima, A. (1980) Effects of 2-deoxy-D-glucose, glucose and insulin on efferent activity in gastric vagus nerve. Expenentia 36, 1197-1198
32. 32 Rayner, C. K., Verhagen, M. A., Hebbard, G. S., Dimatteo, A. C., Doran, S. M and Horowitz, M. (1999) Proximal gastric function in type 1 diabetes mellitus. Effects of nyperglycemia. Gastroenterology 116, A1069
33. 33 Berne, C., Fagius, J. and Niklasson, F. (1989) Sympathetic response to oral carbohydrate administration. Evidence from microelectrode nerve recordings. J. Clin. Invest. 84, 1403-1409
34. 34 Jahnberg, T., Abrahamsson, H., Jansson, G. and Martinson, J. (1977) Gastric relaxatory response to insulin before and after vagotomy. Scand. J. Gastroenterol. 12, 229-233
35. 35 Straathof, J. W., Mearadji, B., Lamers, C. B. and Masclee, A. A. (1998) Effect of CCK on proximal gastric motor function in humans. Am. J. Physiol. 274, G939-G944