Highly potent inhibitors of human cathepsin L identified by screening combinatorial pentapeptide amide collections

European Journal of Biochemistry

Volumn 267, Issue 16, 2000, Pages 5085-5092

  Brinker, Achim ^a,e   Weber, Ekkehard ^b   Stoll, Dieter ^a   Voigt, Jürgen ^a   Müller, Annett ^c,f   Sewald, Norbert ^c   Jung, Günther ^a   Wiesmüller, Karl Heinz ^d   Bohley, Peter ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^c BIELEFELD UNIVERSITY   (Germany)

^d EMC MICROCOLLECTIONS GMBH   (Germany)

^e MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^f EVOTEC BioSystems AG   (Germany)

Author keywords

Cathepsin L inhibitors; Synthetic peptide library

Indexed keywords

CATHEPSIN L; CATHEPSIN L INHIBITOR; ENZYME INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; DRUG DESIGN; DRUG POTENCY; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN SYNTHESIS;

AMIDES; AMINO ACID SEQUENCE; CARCINOMA, NON-SMALL-CELL LUNG; CATHEPSINS; CYSTEINE ENDOPEPTIDASES; ENDOPEPTIDASES; ENZYME INHIBITORS; HUMANS; LUNG NEOPLASMS; OLIGOPEPTIDES; PEPTIDE LIBRARY; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 0033887497     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.2000.01570.x     Document Type: Article

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