Inhibition by an angiogenesis inhibitor, TNP-470, of the growth of a human hepatoblastoma heterotransplanted into nude mice

Journal of Pediatric Surgery

Volumn 35, Issue 8, 2000, Pages 1198-1204

  Matsusaka, Satoshi ^a   Nakasho, Keiji ^a   Terada, Nobuyuki ^a   Sugihara, Ayako ^a   Tsujimura, Tohru ^a   Takanashi, Tadaaki ^a   Uematsu, Kunio ^a   Okamoto, Eizo ^a   Toyosaka, Akihiko ^a  

^a HYOGO COLLEGE OF MEDICINE   (Japan)

Author keywords

Angiogenesis; Hepatoblastoma; TNP 470; Transplantation

Indexed keywords

ANGIOGENESIS INHIBITOR; FUMAGILLOL CHLOROACETYLCARBAMATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER INHIBITION; CELL PROLIFERATION; DRUG EFFECT; ENDOTHELIUM CELL; FEMALE; HEPATOBLASTOMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; TUMOR CELL; TUMOR VOLUME;

EID: 0033883905     PISSN: 00223468     EISSN: None     Source Type: Journal    
DOI: 10.1053/jpsu.2000.8726     Document Type: Article

References (27)

1. Hepatoblastoma and hepatocarcinoma in infancy and childhood. Report of 47 cases
2. Liver tumours in children in particular reference to hepatoblastoma and hepatocellular carcinoma. American Academy of Pediatrics Surgical Survey Section-1974
3. Hepatoblastoma and hepatocarcinoma in children: Analysis of a series of 29 cases
4. Preoperative chemotherapy in 'unresectable' hepatoblastoma
5. Chemotherapy can convert unresectable hepatoblastoma
6. Complete resection before development of drug resistance is essential for survival from advanced hepatoblastoma - A report from the German Cooperative Pediatric Liver Tumor Study HB-89
7. Establishment of a human hepatoblastoma model in athymic nude mice. Producibility of fatty acid-binding protein, α-fetoprotein, and α 1-acid glycoprotein
8. Proliferation and differentiation of a human hepatoblastoma transplanted in the nude mouse
9. Successful transplantation of human hepatoblastoma into immunodeficient mice
10. Comparative activity of cisplatin, ifosfamide, doxorubicin, carboplatin and etoposide in heterotransplanted hepatoblastoma
11. Altered expression of resistance associated genes in hepatoblastoma xenografts incorporated into mice following treatment with adriamycin or cisplatin
12. Antitumor effect of hepatocyte growth factor on hepatoblastoma
13. Paclitaxel: An effective antineoplastic agent in the treatment of xenotransplanted hepatoblastoma
14. Tumor angiogenesis
15. What is the evidence that tumors are angiogenesis dependent?
16. TNP-470 (AMG-1470): Mechanisms of action and early clinical development
17. Therapeutic potential of the anti-angiogenesis drug TNP-470
18. Significant inhibition of endothelial cell growth in tumor vasculature by an angiogenesis inhibitor, TNP-470 (AGM-1470)
19. Effect of angiogenesis inhibitor TNP-470 on the progression of human gastric cancer xenotransplanted into nude mice
20. Hepatoblastoma: An immunohistochemical and ultrastructural study
21. A cytokeratin-immunohistochemical study of hepatoblastoma
22. Immunohistochemical evaluation of hepatoblastomas with use of the hepatocyte-specific marker, hepatocyte paraffin 1, and the polyclonal anti-carcinoembryonic antigen
23. Inhibition of tumor growth and metastasis of rodent tumors by the angiogenesis inhibitor O-(chloroacetyl-carbamoyl) fumagillol (TNP-470, AGM-1470)
24. Antitumor effects of angiogenesis inhibitor O-(chloroacetyl-carbamoyl) fumagillol (TNP-470) against murine renal cell carcinoma
25. Anti-tumor effect of angiogenesis inhibitor TNP-470 on the human nasopharyngeal carcinoma cell line N9C/HK1