Histologic determinants of monoethylglycinexylidide formation in patients with chronic hepatitis C

Therapeutic Drug Monitoring

Volumn 22, Issue 4, 2000, Pages 455-459

  Testa, Roberto ^a,c   Giannini, Edoardo ^a   Ceppa, Paola ^b   Botta, Federica ^a   Romagnoli, Paola ^a   Fasoli, Alberto ^a   Risso, Domenico ^b  

^a UNIVERSITY OF GENOA   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

^c Gastroenterology Unit   (Italy)

Author keywords

Chronic Hepatitis C; Fibrosis; Histology; Lidocaine; Liver; MEGX

Indexed keywords

DEETHYLLIDOCAINE;

ADULT; ARTICLE; FEMALE; HEPATITIS C; HISTOLOGY; HUMAN; LIVER FIBROSIS; LIVER FUNCTION TEST; LIVER INJURY; LIVER METABOLISM; LIVER NECROSIS; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROGNOSIS;

ADULT; AGED; FEMALE; HEPATITIS C, CHRONIC; HUMANS; LIDOCAINE; MALE; MIDDLE AGED; REGRESSION ANALYSIS;

EID: 0033867083     PISSN: 01634356     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007691-200008000-00015     Document Type: Article

References (28)

1. Review article: Quantitative tests of liver function
2. Use of hepatic lidocaine metabolism to monitor patients with chronic liver disease
3. Hepatitis C
4. The pathology of hepatitis C
5. Histopathologic findings in chronic hepatitis C
6. Lidocaine metabolism in human liver microsomes by cytochrome P450IIIA4
7. Measuring lidocaine metabolite monoethylglycinexylidide as a quantitative index of hepatic function in adults with chronic hepatitis and cirrhosis
8. Formation kinetics of the lidocaine metabolite (MEGX) in patients with chronic active hepatitis and cirrhosis
9. Hepatic lidocaine metabolism and liver histology in patients with chronic hepatitis and cirrhosis
10. Monoethylglycinexylidide production as a measure in predicting hepatic histology
11. Predictors of one-year pretransplant survival in patients with cirrhosis
12. Hepatic lidocaine metabolism and complications of cirrhosis
13. Monoethylglycinexylidide test: A prognostic indicator of survival in cirrhosis
14. Can the MEGX test and serum bile acids improve the prognostic ability of Chid-Pugh's score in liver cirrhosis?
15. The monoethylglycine xylidide test for grading of liver cirrhosis
16. Classification of chronic hepatitis: Diagnosis, grading and staging
17. Assessment of lidocaine metabolite formation in comparison with other quantitative liver function tests
18. Hepatic lidocaine metabolism in chronic hepatitis C virus hepatitis with or without steatosis
19. Quantitation of intrinsic drug-metabolizing capacity in human liver biopsy specimens: Support for the intact-hepatocyte theory
20. Assessment of monoethylglycinexylidide as measure of liver function for patients with chronic viral hepatitis
21. Monoethylglycinexylidide formation measurement as a hepatic function test to assess severity of chronic liver disease
22. Toward evidence-based medical statistics 1: The p value fallacy
23. The pharmacokinetics and pharmacodynamics of lignocaine and MEGX in Healthy subjects
24. Lidocaine elimination and monoethylglycinexylidide formation in patients with chronic hepatittis or cirrhosis
25. Determinants of drug disposition in patients with cirrhosis
26. The natural course of chronic hepatitis C: Implications for clinical practice
27. The effect of age on plasma MEGX concentrations
28. Influence of gender on the monoethylglycinexylidide test in normal subjects and liver donors