Histopathologic findings in chronic hepatitis C

Journal of Hepatology, Supplement

Volumn 24, Issue 2, 1996, Pages 35-42

  Fischer, Hans Peter ^a   Willsch, Elmar ^a   Bierhoff, Erhard ^a   Pfeifer, Ulrich ^a  

^a UNIVERSITY OF BONN   (Germany)

Author keywords

Coinfection with HIV; Differential diagnosis; Hepatitis C; Histomorphology

Indexed keywords

HEPATITIS B ANTIGEN; RECOMBINANT ALPHA INTERFERON; VIRUS ANTIGEN; VIRUS PROTEIN; VIRUS RNA;

ALCOHOL LIVER CIRRHOSIS; ANTIGEN DETECTION; AUTOPSY; CONFERENCE PAPER; DIFFERENTIAL DIAGNOSIS; HEPATITIS B; HEPATITIS C; HEPATITIS C VIRUS; HISTOPATHOLOGY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOHISTOCHEMISTRY; INFLAMMATION; LIVER BIOPSY; LIVER CIRRHOSIS; LIVER DISEASE; LIVER FIBROSIS; PRIORITY JOURNAL;

CHRONIC DISEASE; DIAGNOSIS, DIFFERENTIAL; HEPATITIS C; HIV INFECTIONS; HUMANS; INTERFERON-ALPHA;

EID: 0029791913     PISSN: 01695185     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (37)

1. Ludwig J. Practical liver biopsy interpretation: diagnostic algorithms. Chicago: American Society of Clinical Pathologists, 1992.
2. Bianci L, Gudat F. Chronic hepatitis. In: MacSween R, Anthony P, Scheuer P, Burt A, Portmann B, eds. Pathology of the Liver. Edinburgh: Churchill Livingstone, 1994: 349-95.
3. Kobayashi K, Hashimoto E, Ludwig J, Hisamitsu T, Obata H. Liver biopsy features of acute hepatitis C compared with hepatitis A, B, and non-A, non-B, non-C. Liver 1993; 13: 69-72.
4. Scheuer PJ. Viral hepatitis. In: MacSween R, Anthony P, Scheuer P, Burt A, Portmann B, eds. Pathology of the Liver. Edinburgh: Churchill Livingstone, 1994: 243-68.
5. Dhillon AP, Dusheiko GM. Pathology of hepatitis C virus infection. Histopathology 1995; 26: 297-309.
6. De Groote J, Desmet VJ, Gedigk P, Popper H, Scheuer PJ, Thaler N, Korb G, Poulsen H, Schmid M, Uehlinger E, Wepler \V. A classification of chronic hepatitis. Lancet 1968; 2: 626-8.
7. Ludwig J. The nomenclature of chronic active hepatitis: an obituary. Gastroenterology 1993; 105: 274-8.
8. Desmet VJ, Gerber M, Hoofnagle JH, Manns M, Scheuer PJ. Classification of chronic hepatitis: diagnosis, grading and staging. Hepatology 1994; 19: 1513-20.
9. Knodell RG, Ishak KG, Black WC, Chen TS, Craig R, Kaplowitz N, Kiernan TVV, Wollman J. Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis. Hepatology 1981; 1: 431-5.
10. Schmid M, Flury R, Bühler H, Havelka J, Grob PJ, Heitz PU. Chronic viral hepatitis B and C: an argument against the conventional classification of chronic hepatitis. Virchows Arch 1994; 425: 221-8.
11. Bach N, Thung SN, Schaffner F. The histological features of chronic hepatitis C and autoimmune chronic hepatitis: a comparative analysis. Hepatology 1991; 15: 572-7.
12. Scheuer PJ, Ashrafzadeh P, Sherlock S, Brown D, Dusheiko GM. The pathology of hepatitis C. Hepatology 1992; 15: 567-71.
13. Czaja AJ, Herschel A, Carpenter HA. Sensitivity, specificity, and predictability of biopsy interpretations in chronic hepatitis. Gastroenterology 1993; 105: 1824-32.
14. Lefkowitch JH, Schiff ER, Davis GL, Perrillo RP, Lindsay K, Bodenheimer HC, Baiart LA, Ortego TJ, Payne J, Dienstag JL, Gibas A, Jacobson IM, Tamburro CH, Carey W, O'Brien C, Sampliner R, Van Thiel, DH, Feit D, Albrecht J, Meschievitz C, Sanghvi B, Vaughan RD, and the Hepatitis Interventional Therapy Group. Pathological diagnosis of chronic hepatitis C: A multicenter comparative study with chronic hepatitis B. Gastroenterology 1993; 104: 595603.
15. Vyberg M. The hepatitis-associated bile duct lesion. Liver 1993; 13: 289-301.
16. Ruebner BH, Montgomery CK, French S\V. Diagnostic Pathology of the Liver and Biliary Tract, 2nd Edn. New York: Hemisphere Publishing, 1991.
17. Vyberg M, Leth P. Ubiquitin: an immunohistochemical marker of Mallory bodies and alcoholic liver disease. APMIS Suppl. 1991; 23: 46-52.
18. Nuovo GJ, Lidonnici K, MacConnell P, Lane B. Intracellular localization of polymerase chain reaction (PCR)-amplified hepatitis C cDNA. Am J Surg Pathol 1993; 17: 683-90.
19. Hiramatsu N, Hayashi N, Haruna Y, Kasahara A, Fusamoto H, Mori C, Fuke I, Okayama H, Kamada T. Immunhistochemical detection of hepatitis C virus-infected hepatocytes in chronic liver disease with monoclonal antibodies to core, envelope and NS3 regions of the heptitis C virus genome. Hepatology 1992; 16:306-11.
20. Yap SH, Willems M, van den Oord J, Habets W, Middeldorp JM, Hellings JA, Nevens F, Moshage H, Desmet V, Fevery J. Detection of hepatitis C virus antigen by immuno-histochemical staining: a histological marker of hepatitis C virus infection. J Hepatology 1994; 20: 275-81.
21. Blight K, Lesniewski RR, LaBrooy JT, Cowans EJ. Detection and distribution of hepatitis C-specific antigens in naturally infected liver. Hepatology 1994; 20: 553-7.
22. Blight K, Rowland R, Hall P, Lesniewski RR, Trowbridge R, LaBrooy JT, Gowans EJ. Immunohistochemical detection of the NS4 antigen of hepatitis C virus and its relation to histopathology; Am J Pathol 1993; 143:1548-73.
23. Uchida T, Shikata T, Tanaka E, Kiyosawa K. Immunoperoxidase staining of hepatitis C virus in formalin-fixed, paraffinembedded needle liver biopsies. Virchows Arch 1994; 424: 465-9.
24. Nouri-Aria KT, Sallie R, Mizokami M, Portmann BC, Williams R. Intrahepatic expression of hepatitis C virus antigens in chronic liver disease. J Pathol 1995; 175: 77-83.
25. MacMahon RFT, Yates AJ, McLindon J, Babbs C, Love EM, Warnes TW. The histopathological features of asymptomatic hepatitis C virus-antibody positive blood donors. Histopathology 1994; 24: 517-24.
26. Naito M, Hayashi N, Hagiwara H, Hiramatsu N, Kasahara A, Fusamoto H, Kamada T. Serum hepatitis C virus RNA quantity and histological features of hepatitis C virus carriers with persistently normal ALT levels. Hepatology 1994; 19: 871-5.
27. Alter MJ, Margolis HS, Krawcynski K, Judson FN, Mares A, Alexander \VJ, Hu PY, Miller JK, Gerber M, Sampliner RE, Meeks EL, Beach MJ. The natural history of community-acquired hepatitis C in the United States. N Engl J Med 1992; 327:1899-1905.
28. Di Bisceglie AM, Goodman ZD, Ishak KG, Hoofnagle JH, Melpolder JJ, Alter HJ. Long-term clinical and histopathological follow-up of chronic posttransfusion hepatitis. Hepatology 1991; 14: 969-74.
29. Davis GL, Baiart LA, Schiff ER, Lindsay K, Bodenheimer HC, Perrillo RP, Carey W, Jacobson IM, Payne J, Dienstag JL, VanThiel DH, Tamburro C, Lefkowitch J, Albrecht J, Mechievitz C, Ortego TJ, Gibas A. Treatment of chronic hepatitis C with recombinant Interferon alpha. A multicenter randomized, controlled trial. N Engl J Med 1989; 321: 1501-6.
30. Di Bisceglie AM, Martin P, Kassianidies C, Lisker-Melman M, Murray L, RN, Waggoner J, Goodman Z, Banks SM, Hoofnagle JH. Recombinant interferon alpha therapy for chronic hepatitis C. N Engl J Med 1989; 321: 1506-10.
31. Gallorini A, Plebani M, Pontisso P, Chemello L, Masiero M, Mantovani G, Albert! A. Serum markers of hepatic fibrogenesis in chronic hepatitis type C treated with alpha-2A interferon. Liver 1994; 14: 257-64.
32. Reichard O, Glaumann H, Norkrans G, Wejstal R, Fryden A, Schvarcz R, Weiland O. Histological outcome in patients with chronic hepatitis C given a 60-week interferon alpha-2b treatment course. Liver 1994: 14: 169-74.
33. Hopf U, Küther S, König V, Heuft H, Berg T, Bauditz J, Soltani K, Lobeck H, Huhn D. Langzeitbeobachtung der chronischen Hepatitis C nach Behandlung mit rekombinantem Interferon alpha-2a. Z Gastroenterol 1994; 32: 425-30.
34. Marcellin P, Boyer N, Degott C, Martinot-Peignoux M, Duchatelle V, Giostra E, Areias J, Erlinger S, Benhamou JP. Long-term histologie and viral changes in patients with chronic hepatitis C who responded to alpha interferon. Liver 1994; 14: 302-7.
35. Eyster ME, Diamondstone LS, Lien JM, Ehmann WC, Quan S, Goedert JJ for the Multicenter Hemophilia Cohort Study; Natural history of hepatitis C virus infection in multitransfused hemophiliacs: effect of coinfection with human immunodeficiency virus; J Acquired Immune Defic Syndromes 1993; 6: 602-10.
36. Guido M, Rugge M, Fattowich G, Rochetto P, Cassaro M, Chemello L, Noventa F, Guistina G, Alberti A. Human immunodeficiency virus infection and hepatitis C pathology. Liver 1994; 14: 314-9.
37. Rockstroh JK, Spengler U, Bierhoff E, Fischer HP, Hammerstein U, Brackmann HH, Sauerbruch T. Stellt eine cholestatische Verlaufsform der Hepatitis bei HIV/HCV-doppelinfizierten Hämophilen einen ungünstigen Prognosefaktor dar? Z Gastroenterol 1995; 33: 85.