Time window control: A model for cerebellar function based on synchronization, reverberation, and time slicing

Progress in Brain Research

Volumn 124, Issue , 2000, Pages 275-297

  Kistler, Werner M ^a   Van Hemmen, J Leo ^b   De Zeeuw, Chris I ^c  

^a EPFL   (Switzerland)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID RECEPTOR;

CENTRAL NERVOUS SYSTEM DEPRESSION; CEREBELLUM; CLIMBING FIBER; CONFERENCE PAPER; GRANULE CELL; INHIBITORY POSTSYNAPTIC POTENTIAL; LONG TERM POTENTIATION; MODEL; NONHUMAN; PLASTICITY; PRIORITY JOURNAL; PURKINJE CELL; SYNAPSE;

EID: 0033862543     PISSN: 00796123     EISSN: None     Source Type: Book Series    
DOI: 10.1016/s0079-6123(00)24023-5     Document Type: Conference Paper

References (71)

1. Albus, J.S. (1971) A theory of cerebellar function. Math. Biosci., 10: 25-61.
2. Axelrad, H. and Korn, H. (1982) Field effect and chemical transmission: dual inhibition action of basket cells in the rat cerebellar cortex. Exp. Brain Res. Suppl., 6: 412-439.
3. Bell, C.C. and Kawasaki, T. (1972) Relations among climbing fiber responses of nearby Purkinje cells. J. Neurophysiol., 35: 155-169.
4. Bell, C.C., Han, V.Z., Sugawara, Y. and Grant, K. (1997) Synaptic plasticity in a cerebellum-like structure depends on temporal order. Nature, 387: 278-281.
5. Braitenberg, V. (1967) Is the cerebellar cortex a biological clock in the millisecond range? In: C.A. Fox and R.S. Snider (Eds.), Progress in Brain Research 25: 334-346.
6. Braitenberg, V. (1993) The cerebellar network: attempt at a formalization of its structure. Network, 4: 11-17.
7. Braitenberg, V., Heck, D. and Sultan, F. (1997) The detection and generation of sequences as a key to cerebellar function, experiments and theory. Behav. Brain Sci., 20: 229-277.
8. Buonomano, D.V. (1994) Neural network model of the cerebellum: temporal discrimination and the timing of motor responses. Neural Comput., 6: 38-55.
9. A receptors. J. Neurosci. Res., 50: 1053-1062.
10. Carr, C.E. (1993) Processing of temporal information in the brain. Annu. Rev. Neurosci., 16: 223-243.
11. De Zeeuw, C.I. and Berrebi, A.S. (1995) Postsynaptic targets of Purkinje cell terminals in the cerebellar and vestibular nuclei of the rat. Eur. J. Neurosci., 7(11): 2322-2333.
12. De Zeeuw, C.I., Holstege, J.C., Ruigrok, T.J. and Voogd, J. (1989). Ultrastructural study of the GABAergic, cerebellar, and mesodiencephalic innervation of the cat medial accessory olive: anterograde tracing combined with immunocytochemistry. J. Comp. Neurol., 284(1): 12-35.
13. De Zeeuw, C.I., Lang, E.J., Sugihara, I., Ruigrok, T.J., Eisenman, L. M., Mugnaini, E. and Llinás, R. (1996). Morphological correlates of bilateral synchrony in the rat cerebellar cortex. J. Neurosci., 16(10): 3412-3426.
14. De Zeeuw, C.I., Alphen van, A.M., Hawkins, R.K. and Ruigrok, T.J.H. (1997) Climbing fiber collaterals contact neurons in the cerebellar nuclei that provide a GABAergic feedback to the inferior olive. Neuroscience, 80: 981-986.
15. De Zeeuw, C.I., Hansel, C., Bian, F., Koekkoek, S.K., van Alphen, A.M., Linden, D.J. and Oberdick, J. (1998a) Expression of a protein kinase C inhibitor in Purkinje cells blocks cerebellar LTD and adaptation of the vestibulo-ocular reflex. Neuron, 20(3): 495-508.
16. De Zeeuw, C.I., Simpson, J.I., Hoogenraad, C.C., Galjart, N., Koekkoek, S.K.E. and Ruigrok, T.J.H. (1998b) Micro-circuitry and function of the inferior olive. Trends Neurosci., 21: 391-400.
17. Eccles, J.C., Llinás, R., Sasaki, K. and Voorhoeve, P.E. (1966) Interaction experiments on the responses evoked in Purkinje cells by climbing fibres. J. Physiol. (Lond.), 182(2): 297-315.
18. Farrant M. and Cull-Candy S. (1993) GABA receptors, granule cell and genes. Nature, 361: 302-303.
19. Fiala, J.C., Grossberg, S. and Bullock, D. (1996) Metabotropic glutamate receptor activation in cerebellar Purkinje cells as substrate for adaptive timing of the classically conditioned eye-blink response. J. Neurosci., 16: 3760-3774.
20. Gabbiani, R, Midtgaard, J. and Knoepfl, T. (1994) Synaptic integration in a model of cerebellar granule cells. J. Neurophys., 72: 999-1009.
21. Gerstner, W. and van Hemmen, J.L. (1992) Associative memory in a network of 'spiking' neurons. Network, 3: 139-164.
22. Gerstner, W. and van Hemmen, J.L. (1994) Coding and information processing in neural networks. In : E. Domany, J.L. van Hemmen and K. Schulten (Eds.), Models of Neural Networks II. Springer, New York.
23. Gerstner, W., Kempter, R., van Hemmen, J.L. and Wagner H. (1996) A neuronal learning rule for sub-millisecond temporal coding. Nature, 384: 76-78.
24. Gerstner, W., Ritz, R. and van Hemmen, J.L., (1993) Why spikes? Hebbian learning and retrieval of time-resolved excitation patterns. Biol. Cybern., 69:503-515.
25. Hebb, D.O. (1949) The Organization of Behavior. Wiley, New York.
26. Hirano, T. (1990) Depression and potentiation of the synaptic transmission between a granule cell and a Purkinje cell in rat cerebellar culture. Neurosci. Lett., 119: 141-144.
27. Ito, M. (1984) The Cerebellum and Neural Control, Raven Press, New York.
28. Jahnsen, H. (1986a) Electrophysiological characterisitcs of neurones in the guinea-pig deep cerebellar nuclei in vitro. J. Physiol. (Lond.), 372: 129-147.
29. Jahnsen, H. (1986b) Extracellular activation and membrane conductances of neurones in the guinea-pig deep cerebellar nuclei in vitro. J. Physiol. (Lond.)., 372: 149-168.
30. Kistler, W.M. (1999) Ein neuronales Modell des Kleinhirns basierend auf Zeitkodierung und synaptischer Plastizität (Munich, Dept. of Physics, TU), Thesis.
31. Kistler, W.M., Gerstner, W. and van Hemmen, J.L. (1997) Reduction of the Hodgkin Huxley equations to a single-variable threshold model. Neural. Comput., 9: 1015-1045.
32. Kistler, W.M. and van Hemmen, J.L. (1999) Delayed reverberation through time windows as a key to cerebellar function. Biol. Cybern., 81: 373-380.
33. Kistler, W.M. and van Hemmen, J.L. (2000) Modeling synaptic plasticity in conjunction with the timing of pre- and postsynaptic action potentials. Neural Comput., 12: 385-405.
34. Korn, H. and Axelrad, H. (1980) Electrical inhibition of Purkinje cells in the cerebellum of the rat. Proc. Natl. Acad. Sci., 77(10): 6244-6247.
35. Lampl, I. and Yarom, Y. (1993) Subthreshold oscillations of the membrane potential: a functional synchronizing and timing device. J. Neurophysiol., 70: 2181-2186.
36. ++ in the induction of cerebellar long-term depression. Neuron, 18: 1025-1038.
37. Llinás, R.R., Baker, R. and Sotelo, C. (1974) Electrotonic coupling between neurons in cat inferior olive. J. Neurophysiol., 37: 560-571.
38. Llinás, R. (1988) The intrinsic electrophysiological properties of mammalian neurons: insights into central nervous system function. Science, 242: 1654-1664.
39. Llinás, R. (1991) The non-continuous nature of movement execution. In: D.R. Humphrey and H.-J. Freund (Eds.), Motor Control: Concepts and Issues, J. Wiley & Sons Ltd, pp. 223-242.
40. Llinás, R. and Mühlethaler, M. (1988a) An electrophysiological study of the in vitro, perfused brain stem-cerebellum of adult guinea-pig. J. Physiol. (Lond.), 404: 215-240.
41. Llinás, R. and Mühlethaler, M. (1988b) Electrophysiology of guinea-pig cerebellar nuclear cells in the in vitro brain stem-cerebellar preparation. J. Physiol. (Lond.), 404: 241-258.
42. Llinás, R. and Sasaki, K. (1989) The functional organization of the olivo-cerebellar system as examined by multiple Purkinje cell recordings. Eur. J. Neurosci., 1: 587-602.
43. Llinás, R. and Yarom, Y. (1981a) EIectrophysiology of mammalian inferior olivary neurones in vitro, different types of voltage-dependent ionic conductances. J. Physiol. (Lond.), 315: 549-567.
44. Llinás, R. and Yarom, Y. (1981b) Properties and distribution of ionic conductances generating electroresponsiveness of mammalian inferior olivary neurones in vitro. J. Physiol. (Lond.), 315: 569-584.
45. Llinás, R. and Yarom Y. (1986) Oscillatory properties of guinea-pig inferior olivary neurones and their pharmacological modulation: an in vitro study. J. Physiol. (Lond.), 376: 163-182.
46. Llinás, R., Lang, E., and Welsh, J.P. (1997) The cerebellum, LTD, and memory: alternative views. Learn. Mem. 3: 445-455.
47. Markram, H., Lübke, J., Frotscher, M. and Sakmann, B. (1997) Regulation of synaptic efficacy by coincidence of post-synaptic APs and EPSPs. Science, 275: 213-215.
48. Marr, D. (1969) A theory of cerebellar cortex. J. Physiol. (Lond.), 202: 437-470.
49. Mastronarde, D.N. (1987) Two classes of single-input X-cells in cat lateral geniculate nucleus. II. Retinal inputs and the generation of receptive-field properties. J. Neurophysiol., 57: 381-413.
50. McCormick, D.A., Clark, G.A., Lavond, D.G. and Thompson, R.F. (1982) Initial localization of the memory trace for a basic form of learning. Proc. Natl. Acad. Sci., 79: 2731-2735.
51. McCormick, D.A. and Huguenard, J.R. (1992) A model of the electrophysiological properties of thalamocortical relay neurons. J. Neurophysiol., 68: 1384-1400.
52. Meek J. (1992) Why run parallel fibers parallel? Teleostean Purkinje cells as possible coincidence detectors in a timing device subserving spatial coding of temporal differences. Neuroscience, 48: 249-283.
53. Moore, J.W., Desmond, J.E. and Berthier, N.E. (1989) Adaptively timed conditioned response and the cerebellum: a neural network approach. Biol. Cybern., 62: 17-28.
54. Murakamil, F., Ozawa, N.N., Katsumaru, H. and Tsukahara, H. (1981) Reciprocal connections between the nucleus interpositus of the cerebellum and precerebellar nuclei. Neurosci. Lett., 25: 209-213.
55. Olsen, J.F. and Suga, N. (1991) Combination-sensitive neurons in the medial geniculate body of the mustached bat: encoding of target range information. J. Neurophysiol., 65: 1275-1296.
56. Palay, S.L. and V. Chan-Palay, V. (1974) Cerebellar Cortex, Springer-Verlag, Berlin. Heidelberg. New York.
57. Perret, S.P., Ruiz, B.P. and Mauk, M.D. (1993) Cerebellar cortex lesions disrupt learning-dependent timing of conditioned eyelid response. J. Neurosci., 13: 1708-1718.
58. Ramón y Cajal, S. (1911) Histologie du Système Nerveux de l'homme et des Vertèbres, Maloine, Paris.
59. Ruigrok, T.J. and Voogd, J. (1995) Cerebellar influence on olivary excitability in the cat. Eur. J. Neurosci., 7(4): 679-693.
60. Sakurai, M. (1987) Synaptic modification of parallel fiber-Purkinje cell transmission in in vitro guinea-pig cerebellar slices. J. Physiol. (Lond.), 394: 463-480.
61. Schreurs, B.G., Oh, M.M. and Alkon, D.L. (1996) Pairing-specific long-term depression of Purkinje cell excitatory postsynaptic potentials results from a classical conditioning procedure in the rabbit cerebellar slice. J. Neurophysiol., 75(3): 1051-1060.
62. Schulman, J.A. and Bloom, F.E. (1981) Golgi cells of the cerebellum are inhibited by inferior olive activity. Brain Res., 210: 350-355.
63. Sugihara, I., Lang, E.J. and Llinas, R. (1993). Uniform olivo-cerebellar conduction time underlies Purkinje cell complex spike synchronicity in the rat cerebellum. J. Physiol. (Lond.)., 470: 243-271.
64. Teune, T.M., van der Burg, J., De Zeeuw, C.I. Voogd, J. and Ruigrok, T.J.H. (1998) Single Purkinje cell can innervate multiple classes of projection neurons in the cerebellar nuclei of the rat: a light microscopic and ultrastructural triple-tracer study in the rat. J. Comp. Neurol., 392(2): 164-178.
65. A receptor α6 subunit. J. Neurosci., 16: 3630-3640.
66. Tsukahara, N., Bando, T., Murakami, F. and Oda, Y. (1983) Properties of cerebello-precerebellar reverberating circuits. Brain Res., 274: 249-259.
67. A receptors between functionally innervated and non-innervated granule neurons in neonatal cerebellar cultures. Brain Res., 714: 49-56.
68. Verveer, C., Hawkins, R.K., Ruigrok, T.J.H. and Zeeuw, C.I. De (1997) Ultrastructural study of the GABAergic and cerebellar input to the nucleus reticularis tegmenti pontis. Brain Res., 766: 289-296.
69. Vos, B.P., Maex, R., Volny-Luraghi, A. and De Schutter, E.D. (1999) Parallel fibers synchronize spontaneous activity in cerebellar Golgi cells. J. Neurosci., 19(11): RC6.
70. Welsh, J.P., Lang, E.J., Suglhara, I. and Llinas, R. (1995). Dynamic organization of motor control within the olivo-cerebellar system. Nature, 374(6521): 453-457.
71. Yeo, C.H. and Hesslow, G. (1998) Cerebellum and conditioned reflexes. Trends Cognit. Sci., 2: 322-330.