A C. elegans mediator protein confers regulatory selectivity on lineage-specific expression of a transcription factor gene

Genes and Development

Volumn 14, Issue 17, 2000, Pages 2161-2172

  Zhang, H ^a   Emmons, S W ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Cell fate; Development; Homeobox gene; Regulation; Transcription

Indexed keywords

COMPLEMENTARY DNA; DNA; TRANSCRIPTION FACTOR;

ARTICLE; CAENORHABDITIS ELEGANS; GENE EXPRESSION REGULATION; GENE MUTATION; GENETIC TRANSCRIPTION; GENOME; HOMEOBOX; INTRON; NEUROBLAST; NONHUMAN; PRIORITY JOURNAL; TRANSCRIPTION REGULATION;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BETA CATENIN; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CARRIER PROTEINS; CELL LINEAGE; CELL NUCLEUS; CYTOSKELETAL PROTEINS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, REPORTER; GENOTYPE; HELMINTH PROTEINS; HOMEODOMAIN PROTEINS; INTRONS; MALE; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; MODELS, BIOLOGICAL; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PHENOTYPE; PROTO-ONCOGENE PROTEINS; SEQUENCE HOMOLOGY, NUCLEIC ACID; SUPPRESSION, GENETIC; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; WNT PROTEINS; ZEBRAFISH PROTEINS;

EID: 0033862225     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.814700     Document Type: Article

References (41)

1. Cell contact regulates neuroblast formation in the Caenorhabditis elegans lateral epidermis
2. Global transcription regulators of eukaryotes
3. Mammalian Srb/Mediator complex is targeted by adenovirus E1A protein
4. The Genetics of Caenorhabditis elegans
5. Genetics of transcriptional regulation in yeast: Connections to the RNA polymerase II CTD
6. HOM-C/Hox genes and four interacting loci determine the morphogenetic properties of single cells in the nematode male tail
7. Posterior pattern formation in C. elegans involves position-specific expression of a gene containing a homeobox
8. Expression of the homeotic gene mab-5 during Caenorhabditis elegans embryogenesis
9. The β-catenin homolog BAR-1 and LET-60 Ras coordinately regulate the Hox gene lin-39 during Caenorhabditis elegans vulval development
10. Cell fate determination in Caenorhabditis elegans ray development
11. Patterning of Caenorhabditis elegans posterior structures by the Abdominal-B homolog, egl-5
12. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
13. The C. elegans gene lin-44, which controls the polarity of certain asymmetric cell divisions, encodes a Wnt protein and acts cell nonautonomously
14. Appendix 1, Genetics
15. Spatial and temporal controls target pal-1 blastomere-specification activity to a single blastomere lineage in C. elegans embryos
16. Hox gene expression in a single Caenorhabditis elegans cell is regulated by a caudal homolog and intercellular signals that inhibit Wnt signaling
17. Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators
18. Interactions of EGF, Wnt, and HOM-C genes specify the P12 neuroectoblast fate in C. elegans
19. A gene involved in the development of the posterior body region of C. elegans
20. Twenty-five years of the nucleosome, fundamental particle of the eukaryote chromosome
21. Caenorhabditis elegans Mediator complexes are required for develomental-specific transcriptional activation
22. POP-1 and anterior-posterior fate decisions in C. elegans embryos
23. Patterning of dopaminergic neurotransmitter identity among Caenorhabditis elegans ray sensory neurons by a TGFβ family signaling pathway and a Hox gene
24. A Wnt signaling pathway controls Hox gene expression and neuroblast migration in C. elegans
25. Efficient gene transfer in C. elegans: Extrachromosomal maintenance and integration of transforming sequences
26. Expression of the caudal gene in the germ line of Drosophila: Formation of an RNA and protein gradient during early embryogenesis
27. Association of an X-chromosome dodecamer insertional variant allele with mental retardation
28. WRM-1 activates the LIT-1 protein kinase to transduce anterior/posterior polarity signals in C. elegans
29. A C. elegans Hox gene switches on, off, on and off again to regulate proliferation, differentiation and morphogenesis
30. MOM-4, a MAP kinase kinase kinase-related protein, activates WRM-1/LIT-1 kinase to transduce anterior/posterior polarity signals in C. elegans
31. sur-2, a novel gene, functions late in the let-60 ras-mediated signaling pathway during Caenorhabditis elegans vulval induction
32. Fundamentally different logic of gene regulation in eukaryotes and prokaryotes
33. Post-embryonic cell lineages of the nematode Caenorhabditis elegans
34. Regulation and cell autonomy during postembryonic development of Caenorhabditis elegans
35. sdc-1: A link between sex determination and dosage compensation in C. elegans
36. A homeotic gene cluster patterns the anteroposterior body axis of C. elegans
37. Selective silencing of cell communication influences anteroposterior pattern formation in C. elegans
38. Regulation of cellular responsiveness to inductive signals in the developing C. elegans nervous system
39. A Wnt signaling system that specifies two patterns of cell migration in C. elegans
40. The role of lin-22, a hairy/enhancer of split homolog, in patterning the peripheral nervous system of C. elegans
41. A transcription factor controlling development of peripheral sense organs in C. elegans