Coinfection of SCID-hu Thy/Liv mice with human herpesvirus 6 and human immunodeficiency virus type 1

Journal of Virology

Volumn 74, Issue 18, 2000, Pages 8726-8731

  Gobbi, A ^a   Stoddart, C A ^a   Locatelli, G ^a   Santoro, F ^a   Bare, C ^a   Linquist Stepps, V ^a   Moreno, M E ^a   Abbey, N W ^a   Herndier, B G ^a   Malnati, M S ^a   McCune, J M ^a   Lusso, P ^a  

^a SAN RAFFAELE HOSPITAL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS DNA; VIRUS RNA;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COMBINED IMMUNODEFICIENCY; CYTOPATHOGENIC EFFECT; HUMAN HERPESVIRUS 6; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; THYMUS; VIRUS INFECTION; VIRUS REPLICATION;

ANIMALS; CYTOPATHOGENIC EFFECT, VIRAL; DNA-BINDING PROTEINS; FLOW CYTOMETRY; HERPESVIRIDAE INFECTIONS; HERPESVIRUS 6, HUMAN; HIV CORE PROTEIN P24; HIV INFECTIONS; HIV-1; HUMANS; IMMUNOHISTOCHEMISTRY; MICE; MICE, SCID; T-LYMPHOCYTES; VIRAL PROTEINS; VIRUS REPLICATION;

EID: 0033862110     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.74.18.8726-8731.2000     Document Type: Article

References (35)

1. The SCID-hu mouse as a model for HIV-1 infection
2. Measles virus infection of thymic epithelium in the SCID-hu mouse leads to thymocyte apoptosis
3. CXCR4 and CCR5 expression delineates targets for HIV-1 disruption of T cell differentiation
4. HIV induces thymus depletion in vivo
5. Suppression of human immunodeficiency virus type 1 replication by human herpesvirus-6
6. Experimental transmission of Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) to SCID-hu Thy/Liv mice
7. Changes in thymic function with age and during the treatment of HIV infection
8. Human T-cell leukemia virus infection of human hematopoietic progenitor cells: Maintenance of virus infection during differentiation in vitro and in vivo
9. Human herpesvirus 6 (HHV-6) causes severe thymocyte depletion in SCID-hu Thy/Liv mice
10. Herpesviruses and AIDS
11. Quantitative image analysis of HIV-1 infection in lymphoid tissue
12. T cell turnover in HIV-1 disease
13. Human immunodeficiency virus-1 infection interrupts thymopoiesis and multilineage hematopoiesis in vivo
14. Active HHV-6 infection in the lymph nodes of HIV-infected patients: In vitro evidence that HHV-6 can break HIV latency
15. Primary infection of human herpesvirus 6 in children with vertical infection of human immunodeficiency virus type 1
16. - intermediate
17. Human herpesvirus 6 inhibits human immunodeficiency virus type 1 replication in cell culture
18. Human herpesvirus 6 (HHV-6)
19. Experimental coinfection in vivo by SIV(SM) and HHV-6(GS) in Macaca nemestrina
20. Productive dual infection of human CD4+ T lymphocytes by HIV-1 and HHV-6
21. Human herpesvirus 6 in AIDS
22. Thymic function in HIV-1 disease
23. High prevalence of thymic tissue in adults with human immunodeficiency virus-1 infection
24. Human cytomegalovirus in a SCID-hu mouse: Thymic epithelial cells are prominent targets of viral replication
25. + T lymphocytes and epidermal cells in SCID-hu mice
26. Infection of the SCID-hu mouse by HIV-1
27. Long-term human hematopoiesis in the SCID-hu mouse
28. Use of standardized SCID-hu Thy/Liv mouse model for preclinical efficacy testing of anti-human immunodeficiency virus type 1 compounds
29. Isolation of a new virus, HBLV, in patients with lymphoproliferative disorders
30. CD46 is a cellular receptor for human herpesvirus 6
31. Detection of human herpesvirus 6 in plasma of children with primary infection and immunosuppressed patients by polymerase chain reaction
32. The human immunodeficiency virus tat gene enhances replication of human herpesvirus-6
33. Human immunodeficiency virus infection of the human thymus and disruption of the thymic microenvironment in the SCID-hu mouse
34. The SCID-hu Thy/Liv mouse: An animal model for HIV-1 infection
35. HIV-1-induced thymocyte depletion is associated with indirect cytopathogenicity and infection of progenitor cells in vivo