Novel pathways in the pathogenesis of respiratory syncytial virus disease

Pediatric Pulmonology

Volumn 30, Issue 2, 2000, Pages 131-138

  Elidemir, Okan ^a   Maciejewski, Stephanie R ^b   Oermann, Christopher M ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b TEXAS CHILDREN S HOSPITAL   (United States)

Author keywords

Bronchiolitis; Cytokines; Interferon gamma; Obstructive airway disease; Pulmonary surfactant; Viral respiratory infection

Indexed keywords

CYTOKINE; GAMMA INTERFERON; LEUKOTRIENE; LUNG SURFACTANT;

ANIMAL EXPERIMENT; ANIMAL MODEL; BRONCHIOLITIS; CELLULAR IMMUNITY; CYTOKINE PRODUCTION; HUMAN; HUMORAL IMMUNITY; IMMUNOREGULATION; MOUSE; NONHUMAN; PATHOGENESIS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; REVIEW; VIRUS INFECTION;

ANIMAL; BRONCHIOLITIS; CHILD; CHILD, PRESCHOOL; DISEASE MODELS, ANIMAL; HUMAN; INFANT; INFANT, NEWBORN; LEUKOTRIENES; MICE; PULMONARY SURFACTANTS; RESPIRATORY SOUNDS; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; RESPIRATORY SYNCYTIAL VIRUS, HUMAN;

EID: 0033860272     PISSN: 87556863     EISSN: None     Source Type: Journal    
DOI: 10.1002/1099-0496(200008)30:2<131::aid-ppul8>3.0.co;2-s     Document Type: Review

References (59)

1. Viral infections and obstructive airway disease in early life
2. Respiratory syncytial virus immunology
3. Experimental models for respiratory syncytial virus infections
4. Animal models of respiratory syncytial virus infection
5. Respiratory syncytial virus affects pulmonary function in Balb/c mice
6. Noninvasive measurement of airway responsiveness in allergic mice using barometric plethysmography
7. Risk factors for respiratory syncytial virus-associated lower respiratory illnesses in the first year of life
8. Respiratory syncytial virus immunoglobulin and monoclonal antibodies in the prevention and treatment of respiratory syncytial virus infection
9. The development of respiratory syncytial virus-specific IgE and the release of histamine in nasopharyngeal secretions after infection
10. Predictive value of respiratory syncytial virus-specific IgE responses for recurrent wheezing following bronchiolitis
11. Allergic predisposition among infants with bronchiolitis
12. Asthma and immunoglobulin E antibodies after respiratory syncytial virus bronchiolitis: A prospective cohort study with matched controls
13. Acute bronchiolitis: Predisposing factors and characterization of infants at risk
14. Respiratory status and allergy 9 to 10 years after acute bronchiolitis
15. Differential immune responses to acute lower respiratory illness in early life and subsequent development of persistent wheezing and asthma
16. Respiratory syncytial viral infection in children with compromised immune function
17. CD4+ T cells clear virus but augment disease in mice infected with respiratory syncytial virus. Comparison with the effects of CD8+ T cells
18. Defective regulation of immune responses in respiratory syncytial virus infection
19. T cell subset analysis in peripheral blood of children with RSV bronchiolitis
20. Mucosal T cell distribution during infection with respiratory syncytial virus
21. TH1 and TH2 cells: Different patterns of lymphokine secretion lead to different functional properties
22. T-cell cytokine profile evaluated at the single cell level in BAL and blood in allergic asthma
23. Phenotypic and functional characterization of T cell lines specific for individual respiratory syncytial virus proteins
24. Distinct types of lung disease caused by functional subsets of antiviral T cells
25. Different patterns of cytokine induction in cultures of respiratory syncytial (RS) virus-specific human TH cell lines following stimulation with RS virus and RS virus proteins
26. Eosinophil degranulation in the respiratory tract during naturally acquired respiratory syncytial virus infection
27. Respiratory syncytial virus infection in infants is associated with predominant Th-2-like response
28. Serum eosinophil cationic protein and interleukin-5 in children with bronchial asthma and acute bronchiolitis
29. Cellular immunity is activated and a TH-2 response is associated with early wheezing in infants after bronchiolitis
30. Increased production of IFN-gamma and cysteinyl leukotrienes in virus- induced wheezing
31. Host genetic determinants of vaccine-induced eosinophilia during respiratory syncytial virus infection
32. The role of interferon gamma in the pathogenesis of primary respiratory syncytial virus infection in Balb/c mice
33. Th1 and Th2 cytokine induction in pulmonary T cells during infection with respiratory syncytial virus
34. Respiratory syncytial virus infection results in airway hyperresponsiveness and enhanced airway sensitization to allergen
35. T cell source of type 1 cytokines determines illness patterns in respiratory syncytial virus-infected mice
36. IL-12 treatment attenuates T helper cell type 2 and B cell responses but does not improve vaccine-enhanced lung illness
37. Virus-specific CD8+ T lymphocytes downregulate T helper cell type 2 cytokine secretion and pulmonary eosinophilia during experimental murine respiratory syncytial virus infection
38. CD8+ T cells control Th2-driven pathology during pulmonary respiratory syncytial virus infection
39. Cellular responses to interferon-gamma
40. In vivo blockade of gamma interferon affects the influenza virus- induced humoral and the local cellular immune response in lung tissue
41. Interferon production by human mononuclear leukocytes: Differences between respiratory syncytial virus and influenza viruses
42. The release of leukotrienes in the respiratory tract during infection with respiratory syncytial virus: Role in obstructive airway disease
43. TCR-stimulated naive human CD4+ 45RO- T cells develop into effector cells that secrete IL-13, IL-5, and IFN-gamma, but no IL-4, and help efficient IgE production by B cells
44. Development of airway hyperresponsiveness is dependent on interferon- gamma and independent of eosinophil infiltration
45. Differential effects of endogenous and exogenous interferon-gamma on immunoglobulin E, cellular infiltration, and airway responsiveness in a murine model of allergic asthma
46. Effects of IFN on human eosinophils in comparison with other cytokines. A novel class of eosinophil activators with delayed onset of action
47. The role and contribution of leukotrienes in asthma
48. Enhancement by parainfluenza 3 infection of contractile responses to substance P and capsaicin in airway smooth muscle from the guinea pig
49. Interleukin-11: Stimulation in vivo and in vitro by respiratory viruses and induction of airways hyperresponsiveness
50. Persistence of airway hyperresponsiveness and viral antigen following respiratory syncytial virus bronchiolitis in young guinea-pigs
51. Diminished lung function as a predisposing factor for wheezing respiratory illness in infants
52. Surfactant: A review of its functions and relevance in adult respiratory disorders
53. Surfactant abnormalities in infants with severe viral bronchiolitis
54. Surfactant dysfunction develops in BALB/c mice infected with respiratory syncytial virus
55. Pulmonary surfactant maintains patency of conducting airways in the rat
56. Disruption of pulmonary surfactant's ability to maintain openness of a narrow tube
57. Treatment of respiratory failure due to respiratory syncytial virus pneumonia with natural surfactant
58. Porcine-derived surfactant treatment of severe bronchiolitis