Effect of Thiazinotrienomycin B, an ansamycin antibiotic, on the function of epidermal growth factor receptor in human stomach tumor cells

Journal of Antibiotics

Volumn 52, Issue 5, 1999, Pages 485-490

  Hosokawa, Nobuo ^a   Yamamoto, Shinobu ^b   Uehara, Yoshimasa ^c   Hori, Makoto ^b   Tsuchiya, Kayoko S ^b  

^a INSTITUTE OF MICROBIAL CHEMISTRY   (Japan)

^b SHOWA PHARMACEUTICAL UNIVERSITY   (Japan)

^c NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANSAMYCIN DERIVATIVE; EPIDERMAL GROWTH FACTOR RECEPTOR; PLASMA PROTEIN; THIAZINOTRIENOMYCIN B; UNCLASSIFIED DRUG;

ARTICLE; BLADDER TUMOR; CELL CYCLE; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE S PHASE; CONTROLLED STUDY; DRUG SPECIFICITY; HELA CELL; HUMAN; HUMAN CELL; LUNG TUMOR; PRIORITY JOURNAL; SERUM; STOMACH TUMOR; TUMOR CELL CULTURE; TUMOR GROWTH;

STREPTOMYCES;

EID: 0033016887     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.7164/antibiotics.52.485     Document Type: Article

References (10)

1. TAHARA, E.: Growth factors and oncogenes in human gastrointestinal carcinomas. J. Cancer Res. Clin. Oncol. 116: 121-131, 1990
2. GURPIDE, E.: Endometrial cancer: biochemical and clinical correlates. J. Natl.Cancer Inst. 83: 405-416, 1991
3. WONG, D. T.: TGF-alpha and oral carcinogenesis. Eur. J. Cancer B Oral Oncol. 29B: 3-7, 1993
4. YOSHIDA, K.; T. TSUDA, T. MATSUMURA, T, TSUJINO, T. HATTORI, H. ITO & E. TAHARA: Amplification of epidermal growth factor receptor (EGFR) gene and oncogenes in human gastric carcinomas. Virchows Arch. B Cell Pathol. Incl. Mol. Pathol. 57: 285-290, 1989
5. YOSHIDA, K.; E. KYO, T. TSUJINO, T. SANO, M. NIIMOTO & E. TAMARA: Expression of epidermal growth factor, transforming growth factor-altha and their receptor genes in human gastric carcinomas; implication for autocrine growth. Jpn. J. Cancer Res. 81: 43-51, 1990
6. HOSOKAWA, N.; H. NAGANAWA, H. IINUMA, T. KANBE & M. HORI: Thiazinotrienomycins, new ansamycin group antibiotics. J. Antibiotics 48: 471-478, 1995
7. TSUCHIYA, S. K.; T. KANBE, M. HORI, Y. UEHARA, Y. TAKAHASHI & T. TAKEUCHI: Distinct effects of clinically used anthracycline antibiotics on ras oncogene-expressed cells. Biol. Pharm. Bull. 16: 908-911, 1993
8. TSUCHIYA, S-.K.; Y. MORIYA, M. HORI, Y. UEHARA & T. TAKEUCHI: Induction by herbimycin A of contact inhibition in v-src-expressed cells. J.Antibiotics 42: 1831-837, 1989
9. LI, P.-M.; H. FUKAZAWA, C. YAMAMOTO, S. MIZUNO, K. TANAKA, M. HORI, S. YAGINUMA, T. SAITO & Y. UEHARA: Method of identifying inhibitors of oncogenic transformation: selective inhibition of cell growth in serum-free medium. Oncogene 8: 1731-1735, 1993
10. CHAJRY, N.; P. M. MARTIN, G. PAGES, C. COCHET, K. AFDEL & Y. BERTHOIS: Relationship between the MAP kinase activity and the dual effect of EGF on A431 cell proliferation. Biochem. Biophys. Res. Commun. 203: 984-990, 1994