Neisseria gonorrhoeae elicits membrane ruffling and cytoskeletal rearrangements upon infection of primary human endocervical and ectocervical cells

Infection and Immunity

Volumn 68, Issue 9, 2000, Pages 5354-5363

  Edwards, J L ^a   Shao, J Q ^a   Ault, K A ^a   Apicella, M A ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN;

ARTICLE; CELL IMMORTALIZATION; CYTOSKELETON; ELECTRON MICROSCOPY; FEMALE; GONORRHEA; HUMAN; HUMAN CELL; NEISSERIA GONORRHOEAE; PINOCYTOSIS; PRIORITY JOURNAL; PROTEIN SYNTHESIS; SEXUAL INTERCOURSE; SEXUALLY TRANSMITTED DISEASE; UTERINE CERVIX BIOPSY; UTERINE ENDOCERVIX;

ACTINS; BACTERIAL ADHESION; CELL MEMBRANE; CELLS, CULTURED; CERVIX UTERI; CYTOSKELETON; EPITHELIAL CELLS; FEMALE; HUMANS; MICROSCOPY, ELECTRON, SCANNING; NEISSERIA GONORRHOEAE; PROTEIN BIOSYNTHESIS;

EID: 0033850043     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.68.9.5354-5363.2000     Document Type: Article

References (58)

1. Salmonella stimulate macrophage macropinocytosis and persist within spacious phagosomes
2. Interactions of gonococci with HeLa cells: Attachment, detachment, replication, penetration, and the role of protein II
3. Interaction of primary human endometrial cells with Neisseria gonorrhoeae expressing green fluorescent protein
4. Non-muscle contractile proteins: The role of actin and myosin in cell motility and shape determination
5. Entry of Shigella flexneri into HeLa cells: Evidence for directed phagocytosis involving actin polymerization and myosin accumulation
6. The role of neisserial Opa proteins in interactions with host cells
7. Cellular and molecular alterations in human epithelial cells transformed by recombinant human papillomavirus DNA
8. Intracellular pathogens and the actin cytoskeleton
9. Scanning electron microscopy of attachment of Neisseria gonorrhoeae colony phenotypes to surfaces of human genital epithelia
10. Ultrastructure study of cervical gonorrhea
11. Common themes in microbial pathogenicity revisited
12. Cytoskeletal rearrangements accompany Salmonella entry into epithelial cells
13. The squamocolumnar transitional zone of the cervix uteri
14. Ruffles induced by Salmonella and other stimuli direct macropinocytosis of bacteria
15. Characterization of paired tumor and non-tumor cell lines established from patients with breast cancer
16. Salmonella invasion of nonphagocytic cells induces formation of macropinosomnes in the host cell
17. Gonococcal opacity protein promotes bacterial entry-associated rearrangements of the epithelial cell actin cytoskeleton
18. Studies on the mechanisms of phagocytosis. II. The interaction of macrophages with anti-immunoglobulin IgG-coated bone marrow-derived lymphocytes
19. Studies on the mechanism of phagocytosis. I. Requirements for circumferential attachment of particle-bound ligands to specific receptors on the macrophage plasma membrane
20. Neisseria gonorrhoeae
21. The pathology of gonorrhoea
22. Ultrastructure analysis of primary human urethral epithelial cell cultures infected with Neisseria gonorrhoeae
23. Gonococcal infections in the adult
24. Interleukin-6 and interleukin-6 soluble receptor regulate proliferation of normal, human papillomavirus-immortalized, and carcinoma-derived cervical cells in vitro
25. Adhesion and invasion by the pathogenic Neisseria
26. Characterization of primary human keratinocytes transformed by human papillomavirus type 18
27. Infection of primary human bronchial epithelial cells by Haemophilus influenzae: Macropinocytosis as a mechanism of airway epithelial cell entry
28. 60Co gamma rays
29. Increased expression of luteinizing hormone/human chorionic gonadotropin receptor gene in human endometrial carcinomas
30. Enrichment of epithelial cells for molecular studies
31. Mechanisms of mucosal invasion by pathogenic Neisseria
32. Gonococcal infections in women
33. Pathogenic neisseriae: Complexity of pathogen-host cell interplay
34. The catalog of human cytokeratins: Patterns of expression in normal epithelia, tumors and cultured cells
35. Comparative biology of intracellular parasitism
36. Endocytosis
37. Interactions of pathogenic Neisseria with host cells. Is it possible to assemble the puzzle?
38. Interaction of pathogenic neisseriae with nonphagocytic cells
39. Host cell interactions and signaling with Neisseria gonorrhoeae
40. Unusual microtubule-dependent endocytosis mechanisms triggered by Campylobacter jejuni and Citrobacter freundii
41. Professional and non-professional phagocytes: An introduction
42. Induced engulfment of Neisseria gonorrhoeae by tissue culture cells
43. The role of clathrin, adaptors, and dynamin in endocytosis
44. Functional conservaton of the secretion and translocation machinery for the virulence proteins of yersiniae, salmonellae, and shigellae
45. Signaling to the actin cytoskeleton
46. Quantitative analysis of membrane cofactor protein (MCP) of complement. High expression of MCP on human leukemia cell lines, which is down-regulated during cell differentiation
47. Endocytosis
48. Human papillomavirus 16 immortalization of normal ectocervical epithelial cells alters retinoic acid regulation of cell growth and epidermal growth factor receptor expression
49. A functional role for ezrin during Shigella flexneri entry into epithelial cells
50. Changing patterns of keratin expression during progression of cervical intraepithelial neoplasia
51. Keratin expression in cervical cancer
52. Gonococcal and meningococcal pathogenesis as defined by human cell, cell culture, and organ culture assays
53. In vivo cytokeratin-expression pattern of stratified squamous epithelium from human papillomavirus-type-16-immortalized ectocervical and foreskin keratin-ocytes
54. Phagocytosis by zippers and triggers
55. Macropinocytosis
56. Mechanisms of Shigella entry into epithelial cells
57. 1 integrin promotes entry of the bacteria into mammalian cells