Biochemical differences between two types of N-acetylglucosamine: →6Sulfotransferases in human colonic adenocarcinomas and the adjacent normal mucosa: Specific expression of a GlcNAc:→6Sulfotransferase in mucinous adenocarcinoma

Glycobiology

Volumn 10, Issue 9, 2000, Pages 919-929

  Seko, Akira ^a,b   Sumiya, Jun Ichi ^a,b   Yonezawa, Suguru ^c   Nagata, Koji ^c   Yamashita, Katsuko ^a,b  

^a SASAKI INSTITUTE   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c KAGOSHIMA UNIVERSITY   (Japan)

Author keywords

Adenocarcinoma; Carcinoembryonic antigen; Mucinous carcinoma; Sulfomucin; Sulfotransferase

Indexed keywords

BENZENE DERIVATIVE; GALACTOSE; GLYCAN DERIVATIVE; MANNOSE; MUCIN; N ACETYLGALACTOSAMINE; N ACETYLGLUCOSAMINE; SULFOTRANSFERASE;

ARTICLE; BIOCHEMISTRY; BIOSYNTHESIS; CARCINOGENESIS; CLINICAL ARTICLE; COLON ADENOCARCINOMA; COLON MUCOSA; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; HUMAN; HUMAN TISSUE; MUCINOUS CARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; SULFATION;

EID: 0033848568     PISSN: 09596658     EISSN: None     Source Type: Journal    
DOI: 10.1093/glycob/10.9.919     Document Type: Article

References (43)

1. Carcinoembryonic antigen, a human tumor marker, functions as an intercellular adhesion molecule
2. Sulfotransferases of two specificities function in the reconstitution of high endothelial cell ligands for L-selectin
3. Identification of an N-acetylglucosamine-6-O-sulfotransferase activity specific to lymphoid tissue: An enzyme with a possible role in lymphocyte homing
4. The role of alpha-lactalbumin and the A protein in lactose synthetase: Unique mechanism for the control of a biological reaction
5. The isolation and identification of the B protein of lactose synthetase as alpha-lactalbumin
6. Sulfated Lewis x determinants as a major structural motif in glycans from LS174T-HM7 human colon carcinoma mucin
7. Enzymatic sulfation of mucus glycoprotein in gastric mucosa. Effect of ethanol
8. Effect of phospholipids on thyroid oligosaccharyltransferase activity and orientation. Evaluation of structural determinants for stimulation of N-glycosylation
9. The enzymatic sulfation of glycoprotein carbohydrate units: Blood group T-hapten specific and two other distinct Gal:3-O-sulfotransferases as evident from specificities and kinetics and the influence of sulfate and occurring in the carbohydrate chain on C-3 sulfation of terminal Gal
10. Characterization of an N-acetylglucosamine-6-O-sulfotransferase from human respiratory mucosa active on mucin carbohydrate chains
11. Presence of sulfate in N-glycosidically linked carbohydrate units of calf thyroid plasma membrane glycoproteins
12. Value of histochemical reactions for mucosubstances in the diagnosis of certain pathological conditions of the colon and rectum
13. Carbohydrate structures of a normal counterpart of the carcinoembryonic antigen produced by colon epithelial cells of normal adults
14. Characterization of a rat corpus sulfotransferase for the 6-O-sulfation of β-D-N-acetylglucosamine residues on oligosaccharides
15. Structure of the O-glycans in GlyCAM-1, an endothelial-derived ligand for L-selectin
16. A novel, high endothelial venule-specific sulfotransferase expresses 6-sulfosialyl Lewis(X), an L-selectin ligand displayed by CD34
17. Significance of sialyl 6-sulfo Lewis x: A new ligand for selectins
18. Isolation of oligosaccharides from human milk
19. Purification and properties of an N-acetylglucosamine-specific lectin from Psathyrella velutina mushroom
20. Characterization of a novel mucin sulphotransferase activity synthesizing sulphated O-glycan core 1, 3-sulphate-Galβ1-3GalNAcα-R
21. Cloning and characterization of a mammalian N-acetylglucosamine-6-sulfotransferase that is highly restricted to intestinal tissue
22. Sialylation and sulfation of the carbohydrate chains in respiratory mucins from a patient with cystic fibrosis
23. a tetrasaccharide sequence
24. Expression of sulfomucins in normal mucosae, colorectal adenocarcinomas and metastases
25. Modulation of bovine milk galactosyltransferase activity by lipids
26. Identification of a major carbohydrate capping group of the L-selectin ligand on high endothelial venules in human lymph nodes as 6-sulfo sialyl Lewis X
27. L-Selectin-carbohydrate interactions, relevant modifications of the Lewis x trisaccharide
28. Quantitative differences in GlcNAc:β1→3 and GlcNAc:β1→4 galactosyltransferase activities between human colonic adenocarcinomas and normal colonic mucosa
29. Occurrence of a sialylglycopeptide and free sialylglycans in hen's egg yolk
30. Identification and characterization of N-acetylglucosamine-6-O-sulfate-specific β1,4-galactosyltransferase in human colorectal mucosa
31. Characterization of a rat liver Golgi sulphotransferase responsible for the 6-O-sulphation of N-acetylglucosamine residues in β-linkage to mannose: Role in assembly of sialyl-galactosyl-N-acetylglucosamine N-linked oligosaccharides
32. Purification and characterization of a glucuronyltransferase involved in the biosynthesis of the HNK-1 epitope on glycoproteins from rat brain
33. Molecular cloning and characterization of an N-acetylglucosamine-6-O-sulfotransferase
34. Human N-acetylglucosamine-6-O-sulfotransferase involved in the biosynthesis of 6-sulfo sialyl Lewis X: Molecular cloning, chromosomal mapping and expression in various organs and tumor cells
35. Regulation of β-D-galactoside α2→3 sialyltransferase activity. The effects of detergents and lysophosphatidates
36. Structural studies of the carbohydrate moieties of carcinoembryonic antigens
37. Carbohydrate structures of NCA-2, a glycoprotein purified from meconium as an antigen cross-reacting with anti-CEA antibody: Occurrence of complex-type sugar chains with the Galβ1→3GlcNAcβ1→3Galβ1[4GlcNAcβ1→ outer chains
38. Cancer cells and metastasis. Carcinoembryonic antigen and related normal antigens
39. Differential production of high molecular weight sulfated glycoproteins in normal colonic mucosa, primary colon carcinoma and metastases
40. Alterations of O-glycan biosynthesis in human colon cancer tissues
41. Phospholipids and UDP-glucuronosyltransferase. Structure/function relationships