Quantitative differences in GlcNAc:β1→3 and GlcNAc:β1→4 galactosyltransferase activities between human colonic adenocarcinomas and normal colonic mucosa

Cancer Research

Volumn 56, Issue 15, 1996, Pages 3468-3473

  Seko, Akira ^a   Ohkura, Takashi ^a   Kitamura, Hiroshi ^b   Yonezawa, Suguru ^b   Sato, Eiichi ^b   Yamashita, Katsuko ^a  

^a SASAKI INSTITUTE   (Japan)

^b KAGOSHIMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AGGLUTININ; BETA GALACTOSIDASE; GALACTOSYLTRANSFERASE; OLIGOSACCHARIDE; URIDINE DIPHOSPHATE GALACTOSE;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; COLON ADENOCARCINOMA; COLON MUCOSA; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN TISSUE; MALE; MICROSOME; PRIORITY JOURNAL;

ACETYLGLUCOSAMINE; ADENOCARCINOMA; AGED; AGED, 80 AND OVER; CARBOHYDRATE SEQUENCE; COLON; COLONIC NEOPLASMS; FEMALE; GALACTOSYLTRANSFERASES; HUMANS; INTESTINAL MUCOSA; KINETICS; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; OLIGOSACCHARIDES;

EID: 0030003950     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Burtin, P., Chavanel, G., and Hirsch-Marie, H. Characterization of a second normal antigen that cross-reacts with CEA. J. Immunol., III: 1926-1928, 1973.
2. Matsuoka, Y., Hara, M., Takatsu, K., and Kitagawa, M. Presence of antigen related to the carcinoembryonic antigen in feces of normal adults. Jpn. J. Cancer Res., 64: 203-206, 1973.
3. Oikawa, S., Nakazato, H., and Kosaki, G. Primary structure of human carcinoembryonic antigen (CEA) deduced from cDNA sequence. Biochem. Biophys. Res. Commun., 142: 511-518, 1987.
4. Sato, C., Miyaki, M., Oikawa, S., Nakazato H., and Kosaki, G. Differential expression of carcinoembryonic antigen and nonspecific crossreacting antigen genes in human colon adenocarcinomas and normal colon mucosa. Jpn. J. Cancer Res., 79: 433-437, 1988.
5. Zimmermann, W., Ortlieb, B., Friedrich, R., and von Kleist, S. Isolation and characterization of cDNA clones encoding the human carcinoembryonic antigen reveal a highly conserved repeating structure. Proc. Natl. Acad. Sci. USA, 84: 2960-2964, 1987.
6. Yamashita, K., Totani, K., Kuroki, M., Matsuoka, Y., Ueda, I., and Kobata, A. Structural studies of the carbohydrate moieties of carcinoembryonic antigens. Cancer Res., 47: 3451-3459, 1987.
7. Yamashita, K., Totani, K., Iwaki, Y., Kuroki, M., Matsuoka, Y., Endo, T., and Kobata, A. Carbohydrate structures of nonspecific cross-reacting antigen-2, a glycoprotein purified from meconium as an antigen cross-reacting with anti-carcinoembryonic antigen antibody: occurrence of complex-type sugar chains with the Galβ1→3GlcNAcβ1→3Galβ1→4GlcNAcβ1→ outer chains. J. Biol. Chem., 264: 17873-17881, 1989.
8. Fukushima, K., Ohkura, T., Kanai, M., Kuroki, M., Matsuoka, Y., Kobata, A., and Yamashita, K. Carbohydrate structures of a normal counterpart of the carcinoembryonic antigen produced by colon epithelial cells of normal adults. Glycobiology, 5: 105-115, 1995.
9. Yamashita, K., Fukushima, K., Sakiyama, T., Murata, F., Kuroki, M., and Matsuoka, Y. Expression of Siaα2→6Galβ1→4GlcNAc residues on sugar chains of glycoproteins including carcinoembryonic antigens in human colon adenocarcinoma: applications of Trichosanthes japonica agglutinin I for early diagnosis. Cancer Res., 55: 1675-1679, 1995.
10. Field, M. C., and Wainwright, L. J. Molecular cloning of eukaryotic glycoprotein and glycolipid glycosyltransferases a survey. Glycobiology, 5: 463-472, 1995.
11. Glasgow, L. R., Paulson, J. C., and Hill, R. L. Systematic purification of five glycosidases from Streptococcus (Diplococcus) pneumoniae. J. Biol. Chem., 252: 8615-8623, 1977.
12. Kobata, A. Isolation of oligosaccharides from human milk. Methods Enzymol., 28: 262-271, 1972.
13. M1-gangliosidosis. Different excretion patterns of oligosaccharides in the urine of type 1 and type 2 subgroups. J. Biol. Chem., 256: 4789-4798, 1981.
14. Kiyohara, T., Terao, T., Shioiri-Nakano, K., and Osawa, T. Purification and characterization of β-N-acetylhexosaminidase and β-galactosidase from Streptococcus 6646K. J. Biochem. (Tokyo), 80: 9-17, 1976.
15. Paulson, J. C., Prieels, J-P., Glasgow, L. R., and Hill, R. L. Stalyl- and fucosyltransferases in the biosynthesis of asparaginyl-linked oligosaccharides in glycoproteins. Mutually exclusive glycosylation by β-galactoside α2→6 sialyltransferase and N-acetylglucosaminide α1→3 fucosyltransferase. J. Biol. Chem., 253: 5617-5624, 1978.
16. Sano, M., Hayakawa, K., and Kato, I. Purification and characterization of an enzyme releasing lacto-N-biose from oligosaccharides with type 1 chain. J. Biol. Chem., 268: 18560-18566, 1993.
17. Goldstein, I. J., and Poretz, R. D. In: I. E. Liener, N. Sharon, and I. J. Goldstein (eds.), The Lectins Properties, Functions, and Applications in Biology and Medicine, pp 33-247. Orlando, FL: Academic Press, 1986.
18. Green, E. D., Brodbeck, R. M., and Baenziger, J. U. Lectin affinity high-performance liquid chromatography. Interactions of N-glycanase-released oligosaccharides with Ricinus communis agglutinin I and Ricinus communis agglutinin II. J. Biol. Chem., 262: 12030-12039, 1987.
19. Sheares, B. T., Lau, J. T. Y., and Carlson, D. M. Biosynthesis of galactosyl-β1,3-N-acetylglucosamine. J. Biol. Chem., 257: 599-602, 1982.
20. Holmes, E. H., Hakomori, S., and Ostrander, G. K. Synthesis of type 1 and 2 lacto series glycolipid antigens in human colonic adenocarcinoma and derived cell lines is due to activation of a normally unexpressed β1→3N-acetylglucosaminyltransferase. J. Biol. Chem., 262: 15649-15658, 1987.
21. Holmes, E. H. Characterization and membrane organization of β1→3- and β1→4-galactosyltransferases from human colonic adenocarcinoma cell lines Colo 205 and SW 403: basis for preferential synthesis of type 1 chain lacto-series carbohydrate structures. Arch. Biochem. Biophys., 270: 630-646, 1989.
22. Sheares, B. T., and Carlson, D. M. Characterization of UDP-galactose 2-acetamido-2-deoxy-D-glucose 3β-galactosyltransferase from pig trachea J. Biol. Chem., 258: 9893-9898, 1983.
23. 3H]N-acetylneuraminic acid, and [acetyl-3H]acetyl-coenzyme A. J. Biol. Chem., 268: 16155-16169, 1993.
24. Hakomori, S. Aberrant glycosylation in tumors and tumor-associated carbohydrate antigens. Adv. Cancer Res., 52: 257-331, 1989.