Thiopental combination treatments for cerebral resuscitation after prolonged cardiac arrest in dogs. Exploratory outcome study

Resuscitation

Volumn 45, Issue 2, 2000, Pages 119-131

  Ebmeyer, Uwe ^a,b   Safar, Peter ^a   Radovsky, Ann ^a   Xiao, Feng ^a   Capone, Antonio ^a   Tanigawa, Koichi ^a   Stezoski, S William ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b OTTO VON GUERICKE UNIVERSITY   (Germany)

Author keywords

Barbiturate; Brain ischemia; Cardiac arrest; Cardiopulmonary resuscitation; Methylprednisolone; Phenytoin

Indexed keywords

METHYLPREDNISOLONE; PHENYTOIN; THIOPENTAL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INJURY; BRAIN ISCHEMIA; CONTROLLED STUDY; DOG; HEART ARREST; HISTOPATHOLOGY; INDUCED HYPOTHERMIA; MALE; NONHUMAN; PRIORITY JOURNAL; RESUSCITATION; SURVIVAL; TREATMENT OUTCOME;

EID: 0033848111     PISSN: 03009572     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0300-9572(00)00173-8     Document Type: Article

References (70)

1. P. Safar Resuscitation of the ischemic brain M.S. Albin Textbook of Neuroanesthesia with Neurosurgical and Neuroscience Perspectives 1997 McGraw-Hill New York 557 593
2. P. Safar Resuscitation from clinical death: pathophysiologic limits and therapeutic potentials Crit. Care Med. 16 1988 923 941
3. Y. Leonov F. Sterz P. Safar Mild cerebral hypothermia during and after cardiac arrest improves neurologic outcome in dogs J. Cereb. Blood Flow Metab. 10 1990 57 70
4. F. Sterz P. Safar S. Tisherman Mild hypothermic cardiopulmonary resuscitation improves outcome after prolonged cardiac arrest in dogs Crit. Care Med. 19 1991 379 389
5. V. Weinrauch P. Safar S. Tisherman Beneficial effect of mild hypothermia and detrimental effect of deep hypothermia after cardiac arrest in dogs Stroke 23 1992 1454 1462
6. K. Kuboyama P. Safar A. Radovsky Delay in cooling negates the beneficial effect of mild resuscitative cerebral hypothermia after cardiac arrest in dogs: a prospective, randomized study Crit. Care Med. 21 1993 1348 1358
7. P. Safar F. Xiao A. Radovsky Improved cerebral resuscitation from cardiac arrest in dogs with mild hypothermia plus blood flow promotion Stroke 27 1996 105 113
8. P. Safar W. Stezoski E.M. Nemoto Amelioration of brain damage after 12 minutes cardiac arrest in dogs Arch. Neurol. 33/2 1976 91 95
9. A.L. Bleyaert E.M. Nemoto P. Safar Thiopental amelioration of brain damage after global ischemia in monkeys Anesthesiology 49 1978 390 398
10. E.M. Nemoto A.L. Bleyaert S.W. Stezoski Global brain ischemia: a reproducible monkey model Stroke 8 1977 558 564
11. A.L. Smith J.T. Hoff S.L. Nielson Barbiturate protection in acute focal cerebral ischemia Stroke 5 1974 1 7
12. J.D. Michenfelder H.J. Milde T.M. Sundt Cerebral protection by barbiturate anesthesia. Used after middle cerebral artery occlusion in Java monkeys Arch. Neurol. 33 1976 345 350
13. F.M. Yatsu I. Diamond C. Graziana Experimental brain ischemia: protection from irreversible damage with a rapid-acting barbiturate (methohexital) Stroke 3 1972 726 732
14. R.L. Wechsler R.D. Dripps S.S. Kety Blood flow and oxygen consumption of the human brain during anesthesia produced by thiopental Anesthesiology 12 1951 308 314
15. 2) by mild hypothermia compared with thiopental J. Neurosurg. Anesthesiol. 8 1996 52 59
16. A.M. Hakim G. Moss Cerebral effects of barbiturate: shift from ‘energy’ to synthesis metabolism for cellular viability Surg. Forum 27 1976 497 499
17. H.B. Demopoulos E.S. Flamm D.D. Pietronigro The free radical pathology and the microcirculation: the major central nervous system disorders Acta Physiol. Scand. 492 Suppl. 1980 91 119
18. A.L. Smith J.J. Marque Anesthetics and cerebral edema Anesthesiology 45 1976 64 72
19. H.M. Shapiro Intracranial hypertension. Therapeutic and anesthetic considerations Anesthesiology 43 1975 445 471
20. M.M. Todd H.S. Chadwick H.M. Shapiro The neurologic effects of thiopental therapy following experimental cardiac arrest in cats Anesthesiology 57 1982 76 86
21. P.J. Feustel M.C. Ingvar J.W. Severinghaus Cerebral oxygen availability and blood flow during middle cerebral artery occlusion: effects of pentobarbital Stroke 12 1981 858 863
22. C.H. Nordstrom G. Calderini S. Rehncrona Effects of phenobarbital anesthesia on post-ischemic cerebral blood flow and oxygen consumption in the rat Acta Neurol. Scand. 64 Suppl. 1977 146 147
23. W.A. Kofke E.M. Nemoto K.A. Hossmann Brain blood flow and metabolism after global ischemia and post-insult thiopental therapy in monkeys Stroke 10 1979 554 560
24. G.K. Shiu J.P. Nemmer E.M. Nemoto Reassessment of brain free fatty acid liberation during global ischemia and its attenuation by barbiturate anesthesia J. Neurochem. 40 1983 880 884
25. M.R. Lin E.M. Nemoto P.D. Kessler Alterations in whole brain cyclic AMP and cerebral cortex inducible cyclic AMP in rats during and after complete global ischemia K. Wildemann S. Hoyer Brain Protection: Morphological, Pathophysiological and Clinical Aspects 1983 Springer–Verlag New York 55
26. S.D. MacMurdo E.M. Nemoto P. Nikki Brain cyclic-AMP and possible mechanisms cerebrovascular dilatation by anesthetics in rats Anesthesiology 55 1981 435 438
27. E.M. Nemoto G.K. Shiu J.P. Nemmer Free fatty acid accumulation in the pathogenesis and therapy of ischemic-anoxic brain injury Am. J. Emerg. Med. 1 1983 175 179
28. H. Breivik P. Safar P. Sands Clinical feasibility trials of barbiturate therapy after cardiac arrest Crit. Care Med. 6 1978 228 244
29. A. Mullie N. Abramson P. Safar Clinical pilot studies of thiopental loading after cardiac arrest Crit. Care Med. (Abstr.) 9 1981 184
30. Brain Resuscitation Clinical Trial (BRCT) I Study Group, Abramson NS, Safar P. Randomized clinical study of thiopental loading in comatose survivors of cardiac arrest. N Engl J Med 1986;314:397–403.
31. S.E. Gisvold P. Safar H.H.L. Hendrickx Thiopental treatment after global brain ischemia in pigtailed monkeys Anesthesiology 60 1984 88 96
32. P. Safar Amelioration of postischemic brain damage with barbiturates Stroke 11 1980 565 568
33. J.A. Aldrete F. Romo-Salas L. Jankowsky Effect of pretreatment with thiopental and phenytoin on postischemic brain damage in rabbits Crit. Care Med. 7 1979 466 470
34. J.P. Cullen J.A. Aldrete L. Jankovsky Protective action of phenytoin in cerebral ischemia Anesth. Analg. 58 1979 165 169
35. +–ATPase activity in global ischemic rat brain J. Neurotrauma 12 1995 231 234
36. H. Kinouchi S. Imaizumi T. Yoshimoto Phenytoin affects metabolism of free fatty acids and nucleotides in rat cerebral ischemia Stroke 21 1990 1326 1332
37. W.C. Taft R.J. Delorenzo R.E. Blair Phenytoin protects against ischemia-produced neuronal cell death Brain Res. 483 1989 143 148
38. H.L. Edmonds Y.D. Jiang P.Y. Zhang Anticonvulsant activity of topiramate and phenytoin in a rat model of ischemia-induced epilepsy Life Sci. 59 1996 PL127, PL131
39. S.A. Chan K.H. Reid A. Schurr Fosphenytoin reduces hippocampal neuronal damage in rat following transient global ischemia Acta Neurochir. (Wien) 140 1998 175 180
40. P.A. Boxer J.J. Cordon M.E. Mann Comparison of phenytoin with noncompetitive N -methyl- d -asparate antagonists in a model of focal brain ischemia in rat Stroke 21 Suppl. III 1990 47 51
41. J. Rataud F. Debarnot V. Mary Comparative study of voltage-sensitive sodium channel blockers in focal ischemia and electric convulsions in rodents Neurosci. Lett. 172 1994 19 23
42. M.G. Vartanian J.J. Gordon N.C. Kupina Phenytoin pretreatment prevents hypoxic-ischemia brain damage in neonatal rats Brain Res. Dev. Brain Res. 95 1996 169 175
43. T. Hayakawa Y. Hamada T. Maihara Phenytoin reduces neonatal hypoxic-ischemic brain damage in rats Life Sci. 54 1994 387 392
44. P. Safar Steroids in brain insults (a partial review) S.A. Villazon J.L.B. Llamosa P.L. Hervella M. Shapiro Critical Care Medicine 1980 Excerpta Medica Amsterdam 164 173
45. M.B. Bracken W.F. Collins D.F. Freeman Efficacy of methylprednisolone in acute spinal cord injury J. Am. Med. Assoc. 251 1984 45 52
46. E.D. Hall The neuroprotective pharmacology of methylprednisolone J. Neurosurg. 76 1992 13 22
47. E.D. Hall J.M. Braughler J.M. McCall Antioxidant effects in brain and spinal cord injury J. Neurotrauma 9 Suppl. 1992 S165 172
48. M. Daneyemez E. Kurt A. Cosar Methylprednisolone and vitamin E therapy in perinatal hypoxic-ischemic brain damage in rats Neuroscience 92 1999 693 697
49. O. Kalayci S. Cataltepe O. Cataltepe The effect of bolus methylprednisolone in prevention of brain edema in hypoxic ischemic brain injury: an experimental study in 7-day-old rat pups Brain Res. 569 1992 112 116
50. G.M. de Courten-Meyers M. Kleinholz K.R. Wagner Efficacious experimental stroke treatment with high-dose methylprednisolone Stroke 25 1994 487 492
51. D. Chyatte N.C. Fode D.A. Nichols Preliminary report: effects of high dose methylprednisolone on delayed cerebral ischemia in patients at high risk for vasospasm after aneurysmal subarachnoid hemorrhage Neurosurgery 21 1987 157 160
52. P. Safar S.E. Gisvold P. Vaagenes Long-term animal models for the study of global brain ischemia A. Wauquier M. Borgers W.K. Amery Protection of Tissues Against Hypoxia 1982 Elsevier Amsterdam 147 170
53. F. Sterz Y. Leonov P. Safar Hypertension with or without hemodilution after cardiac arrest in dogs Stroke 21 1990 1178 1184
54. P. Safar Cerebral resuscitation after cardiac arrest: research initiatives and future directions. A review Ann. Emerg. Med. 22 pt. 2 1993 324 349
55. U. Ebmeyer P. Safar F. Xiao Multifaceted cerebral resuscitation in cardiac arrest dog outcome model. Exploratory series II: hypothermia, hypertension, thiopental anesthesia, phenytoin, steroid, hemodilution and normocapnia Crit. Care Med. (Abstr.) 22 1994 A57
56. K. Oku F. Sterz P. Safar Mild hypothermia after cardiac arrest in dogs does not affect postarrest multifocal cerebral hypoperfusion Stroke 24 1993 1590 1598
57. K. Kuboyama P. Safar K. Oku Mild hypothermia after cardiac arrest in dogs does not affect postarrest cerebral oxygen uptake/delivery mismatching Resuscitation 27 1994 231 244
58. P. Safar N.S. Abramson M. Angelos Emergency cardiopulmonary bypass for resuscitation from prolonged cardiac arrest Am. J. Emerg. Med. 8 1990 55 67
59. Y. Leonov F. Sterz P. Safar Hypertension with hemodilution prevents multifocal cerebral hypoperfusion after cardiac arrest in dogs Stroke 23 1992 45 53
60. A. Radovsky P. Safar F. Sterz Regional prevalence and distribution of ischemic neurons in dog brains 96 hours after cardiac arrest of 0 to 20 minutes Stroke 26 1995 2127 2134
61. F. Xiao P. Safar A. Radovsky Mild protective and resuscitative hypothermia for asphyxial cardiac arrest in rats Am. J. Emerg. Med. 16 1998 17 25
62. W.D. Dietrich R. Busto O. Alonso Intraischemic but not postischemic brain hypothermia protects chronically following global forebrain ischemia in rats J. Cereb. Blood Flow Metab. 13 1993 541 549
63. F. Colbourne D. Corbett Delayed and prolonged post-ischemic hypothermia is neuroprotective in the gerbil Brain Res. 654 1994 265 272
64. F. Colbourne H. Li A.M. Buchan Indefatigable CA1 sector neuroprotection with mild hypothermia induced 6 hours after severe forebrain ischemia in rats J. Cereb. Blood Flow and. Metab. 19 1999 742 749
65. D.W. Marion L.E. Penrod S.F. Kelsey Treatment of traumatic brain injury with moderate hypothermia N. Engl. J. Med. 336 1997 540 546
66. S. Pomeranz P. Safar A. Radovsky The effect of resuscitative moderate hypothermia following epidural brain compression on cerebral damage in a canine outcome model J. Neurosurg. 79 1993 241 251
67. U. Ebmeyer P. Safar A. Radovsky Moderate hypothermia for 48 hours after temporary epidural brain compression injury in a canine outcome model J. Neurotrauma 15 1998 323 336
68. P.A. Steen E.H. Soule J.D. Michenfelder Detrimental effect of prolonged hypothermia in cats and monkeys with and without regional cerebral ischemia Stroke 10 1979 522 529
69. S.E. Gisvold P. Safar H. Alexander Thiopental after brain ischemia in monkeys. Cardiovascular and electroencephalographic effects Acta Anaesth. Scand. 29 3 1985 339 345
70. F. Sterz Y. Leonov P. Safar A. Radovsky W. Stezoski H. Reich G. Shearman T. Greber Effect of excitatory amino acid receptor blocker MK-801 on overall, neurologic, and morphologic outcome after prolonged cardiac arrest in dogs Anesthesiology 71 1989 907 918