Carrier-mediated transport of macrolide antimicrobial agents across Caco-2 cell monolayers

Pharmaceutical Research

Volumn 17, Issue 6, 2000, Pages 761-765

  Saito, Hidetaka ^a   Fukasawa, Yoshiki ^a   Otsubo, Yoko ^a   Yamada, Kenji ^a   Sezaki, Hitoshi ^b   Yamashita, Shinji ^b  

^a TAISHO PHARMACEUTICAL CO LTD   (Japan)

^b SETSUNAN UNIVERSITY   (Japan)

Author keywords

Caco 2 monolayers; Clarithromycin; Erythromycin; In vitro drug permeability; Macrolide; P glycoprotein; Verapamil

Indexed keywords

CLARITHROMYCIN; ERYTHROMYCIN; MACROLIDE; VERAPAMIL;

ACTIVE TRANSPORT; ANTIBIOTIC THERAPY; ARTICLE; DRUG ABSORPTION; DRUG TRANSPORT; HUMAN; HUMAN CELL; INTESTINE ABSORPTION; INTRACELLULAR TRANSPORT; MEMBRANE TRANSPORT; PRIORITY JOURNAL;

ANTI-BACTERIAL AGENTS; CACO-2 CELLS; CYTOCHROME P-450 ENZYME SYSTEM; DRUG CARRIERS; HUMANS; MACROLIDES; MIXED FUNCTION OXYGENASES; P-GLYCOPROTEIN;

EID: 0033844748     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1007550820196     Document Type: Article

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