Hereditary colorectal cancer: Risk assessment and management

Clinical Genetics

Volumn 58, Issue 2, 2000, Pages 89-97

  Hampel, Heather ^a,b   Peltomaki, Paivi ^b  

^a Human Cancer Genetics Program   (United States)

^b OHIO STATE UNIVERSITY   (United States)

Author keywords

Adenoma; Cancer; Colorectal; Familial; Genetic; Hamartoma; Hereditary; Polyposis

Indexed keywords

NONSTEROID ANTIINFLAMMATORY AGENT; SULINDAC;

ADENOMATOUS POLYP; ADULT; BREAST EXAMINATION; CANCER GENETICS; CANCER PATIENT; CANCER RISK; CANCER SCREENING; CANCER SUSCEPTIBILITY; CHEMOPROPHYLAXIS; COLON POLYPOSIS; COLON RESECTION; COLONOSCOPY; COLORECTAL CANCER; DIFFERENTIAL DIAGNOSIS; DNA POLYMORPHISM; ECHOGRAPHY; ENDOMETRIUM CANCER; ENDOSCOPY; FAMILIAL CANCER; FAMILIAL POLYPOSIS; FAMILY; FEMALE; HAMARTOMA; HEALTH CARE PERSONNEL; HUMAN; INFORMATION SCIENCE; JUVENILE POLYP; MALE; MAMMOGRAPHY; MUIR TORRE SYNDROME; PEUTZ JEGHERS SYNDROME; PRACTICE GUIDELINE; PRIORITY JOURNAL; PROCTOCOLECTOMY; REVIEW; RISK ASSESSMENT; SIGMOIDOSCOPY; TUMOR SUPPRESSOR GENE; TURCOT SYNDROME;

COLORECTAL NEOPLASMS; GENETIC PREDISPOSITION TO DISEASE; HUMANS; RISK ASSESSMENT;

EID: 0033843684     PISSN: 00099163     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-0004.2000.580201.x     Document Type: Review

References (63)

1. Clinical features of colorectal carcinoma in cancer family syndrome
2. Natural history of colorectal cancer in hereditary nonpolyposis colorectal cancer (Lynch syndromes I and II)
3. Genetics, natural history, tumor spectrum, and pathology of hereditary nonpolyposis colorectal cancer. An updated review
4. Cancer risk in mutation carriers of DNA-mismatch-repair genes
5. Incidence of hereditary nonpolyposis colorectal cancer and the feasibility of molecular screening for the disease
6. Hereditary nonpolyposis colorectal cancer families not complying with the Amsterdam criteria show extremely low frequency of mismatch-repair-gene mutations
7. Analysis of mismatch repair genes in hereditary non-polyposis colorectal cancer patients
8. A National Cancer Institute workshop on hereditary non-polyposis colorectal cancer syndrome: Meeting highlights and Bethesda guidelines
9. Sensitivity and specificity of clinical criteria for hereditary nonpolyposis colorectal cancer-associated mutations in MSH2 and MLH1
10. Clinical findings with implications for genetic testing in families with clustering of colorectal cancer
11. Strategies for screening for hereditary non-polyposis colorectal cancer
12. Correction for Loukola
13. Clinical surveillance recommendations adopted for HNPCC
14. Recommendations for follow-up care of individuals with an inherited predisposition to cancer: I. Hereditary nonpolyposis colorectal cancer
15. A cost-effectiveness analysis of colorectal screening for hereditary nonpolyposis colorectal carcinoma gene carriers
16. Controlled 15-year trial on screening for colorectal cancer in families with hereditary nonpolyposis colorectal cancer families
17. Familial colorectal cancer in Askenazim due to a hypermutable tract in APC
18. Increased risk for thyroid and pancreatic carcinoma in familial adenomatous polyposis
19. Risk of hepatoblastoma in familial adenomatous polyposis
20. The UK Northern Region genetic register for familial adenomatous polyposis coli: Use of age of onset, congenital hypertrophy of the retinal pigment epithelium, and DNA markers in risk calculations
21. Value of combined phenotypic markers in identifying inheritance of familial adenomatous polyposis
22. Molecular diagnosis of familial adenomatous polyposis
23. Genetic testing and counseling in familial adenomatous polyposis
24. APC gene mutations and extra-intestinal phenotype of familial adenomatous polyposis
25. Lessons from hereditary colorectal cancer
26. Care of patients and their families with familial adenomatous polyposis
27. Knowledge of the adenomatous polyposis coli gene and its clinical application
28. Surveillance of familial adenomatous polyposis patients after ileorectal anastomosis or ileoanal pouch anastomosis
29. Molecular genetic tests as a guide to surgical management of familial adenomatous polyposis
30. Molecular genetic tests in surgical management of familial adenomatous polyposis
31. Management of duodenal adenomas in 98 patients with familial adenomatous polyposis
32. Phase I trial of exisulind (sulindac sulfone, FGN-1) as a chemopreventive agent in patients with familial adenomatous polyposis
33. Alleles of the APC gene: An attenuated form of familial polyposis
34. Phenotypic expression of disease in families that have mutations in the 5' region of the adenomatous polyposis coli gene
35. Restriction of ocular fundus lesions to a specific subgroup of APC mutations in adenomatous polyposis coli patients
36. Intestinal polyposis associated with mucocutaneous pigmentation
37. The molecular basis and clinical aspects of Peutz-Jeghers syndrome
38. STK11 mutations in Peutz-Jeghers' syndrome and sporadic colon cancer
39. Allelic imbalance at the LKB1 (STK11) locus on 19p13.3 in tumours from patients with Peutz-Jeghers' syndrome provides evidence for a hamartoma-(adenoma)-carcinoma sequence
40. Increased risk for cancer in patients with the Peutz-Jeghers syndrome
41. Increased risk for cancer in the Peutz-Jeghers syndrome
42. Cancer and the Peutz-Jeghers syndrome
43. A serine/threonine kinase gene defective in Peutz-Jeghers syndrome
44. Mutations and impaired function of LKB1 in familial and non-familial Peutz-Jeghers syndrome and a sporadic testicular cancer
45. Juvenile polyposis: A precancerous condition
46. Inherited disorders associated with colorectal cancer
47. A survey of phenotypic features in juvenile polyposis
48. Mutations in the SMAD4/DPC4 gene in juvenile polyposis
49. Bannayan-Riley-Ruvalcaba syndrome
50. PTEN mutation spectrum and genotype-phenotype correlations in Bannayan-Riley-Ruvalcaba syndrome suggest a single entity with Cowden syndrome
51. The Cowden syndrome: A clinical and genetic study in 21 patients
52. Cowden's disease: A cutaneous marker of breast cancer
53. Cowden syndrome
54. Thyroid pathologic findings in patients with Cowden disease
55. PTEN and inherited hamartoma-cancer syndromes
56. Variant manifestation of Cowden disease in Japan: Hamartomatous polyposis of the digestive tract with mutation in the PTEN gene
57. Exclusion of PTEN and 10q22-24 as the susceptibility locus for juvenile polyposis syndrome
58. Localization of the gene for Cowden disease to chromosome 10q22-23
59. Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome
60. Germline mutations in PTEN are present in Bannayan-Zonana syndrome