Treatment of lupus in NZB/W F1 mice with monoclonal antibody against Fas ligand

Journal of Autoimmunity

Volumn 14, Issue 2, 2000, Pages 151-157

  Nakajima, Atsuo ^a,b   Hirai, Hiroshi ^a   Kayagaki, Nobuhiko ^b   Yoshino, Shinichi ^a   Hirose, Sachiko ^b,c   Yagita, Hideo ^b,c   Okumura, Ko ^b,c  

^a NIPPON MEDICAL SCHOOL   (Japan)

^b JUNTENDO UNIVERSITY   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Apoptosis; Autoantibody; FasL; Lupus nephritis

Indexed keywords

LIGAND; MONOCLONAL ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY PRODUCING CELL; APOPTOSIS; ARTICLE; IMMUNOLOGICAL TOLERANCE; LUPUS ERYTHEMATOSUS; LUPUS ERYTHEMATOSUS NEPHRITIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 0033843682     PISSN: 08968411     EISSN: None     Source Type: Journal    
DOI: 10.1006/jaut.1999.0356     Document Type: Article

References (45)

1. The Fas death factor
2. Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family
3. Fas and Fas ligand: lpr and gld mutations
4. Fast-FasL interactions; a common pathogenic mechanism in organ-specific autoimmunity
5. The role of Fas in autoimmune diabetes
6. Essential role of the Fas ligand in the development of hepatitis
7. Potential involvement of Fas and its ligand in the pathogenesis of Hashimoto's thyroiditis
8. The Fas counter attack: Fas-mediated T cell killing by colon cancer cells expressing Fas ligand
9. Melanoma cell expression of Fas (Apo-1/CD95) ligand: Implications for tumor immune escape
10. A role for CD95 ligand in preventing graft rejection
11. Fas ligand-induced apoptosis as a mechanism of immune privilege
12. Fas ligand is positioned in mouse uterus and placenta to prevent trafficking of activated leukocytes between the mother and the conceptas
13. Antitumor effect of locally produced CD95 ligand
14. Chemotactic activity of soluble Fas ligand against phagocytes
15. Caspase 1-independent IL-1β release and inflammation induced by the apoptosis inducer Fas ligand
16. Divergent induction of apoptosis and IL-8 secretion in HT-29 cells in response to TNF-α and ligation of Fas antigen
17. The Fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice
18. Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity
19. Fas ligand mutation in a patients with systemic lupus erythematosus and lymphoproliferative disease
20. The apoptosis-1/Fas protein in human systemic lupus erythematosus
21. Polymorphism of murine Fas ligand that affects the biological activity
22. Preferential dependence of autoantibody production in murine lupus on CD86 co-stimulatory molecule
23. Effect of major histocompatibility complex on autoimmune disease of N-2-congenic New Zealand Mice
24. + T helper type 2 and type 0 cells by T helper type 1 cells via Fas/Fas-ligand interaction
25. Unequal death in T helper cell (Th) 1 and Th2 effectors: Th1 but not Th2 undergo rapid Fas/FasL-mediated apoptosis
26. Prevention of autoimmune symptoms in autoimmune-prone mice by elimination of B-1 cells
27. Precursor B cells for autoantibody production in genomically Fas-intact autoimmune disease are not subject to Fas-mediated immune elimination
28. Transgenic expression of Fas in T cells blocks lymphoproliferation but not autoimmune disease in MRL-lpr mice
29. Primary antibody-forming cells and secondary B cells are generated from separate precursor cell subpopulations
30. Cellular basis of in vitro anti-DNA antibody production: Evidence for dependence of IgG-class anti-DNA antibody synthesis in the (NZBxNZW) F1 hybrid
31. Induction of a cationic shift in IgG anti-DNA autoantibodies
32. - T helper cell lines that express the γδ T-cell antigen receptor
33. B-cell and T-cell function in systemic lupus erythematosus
34. Roles of IL-4 and IL-12 in the development of lupus in NZB/W F1 mice
35. Th1 and Th2 subsets equally undergo Fas-dependent and -independent activation-induced cell death
36. Mechanism of intravenous immune globulin therapy in antibody-mediated autoimmune diseases
37. Apoptosis and the kidney
38. HIV-1 kills renal tubular epithelial cells in vitro by triggering an apoptotic pathway involving caspase activation and Fas upregulation
39. Agonistic anti-Fas antibodies induce glomerular cell apoptosis in mice in vivo
40. Expression and function of Fas (CD95) on human renal tubular epithelial cell
41. Glandular and extraglandular expression of the Fas-Fas ligand and apoptosis in patients with sjogren's syndrome
42. Chemokine and renal disease
43. Greatly accelerated lymphadenopathy and autoimmune disease in lpr mice lacking tumor necrosis factor receptor I
44. Mice defective in Fas are highly susceptible to Leishmania major infection despite elevated IL-12 synthesis, strong Th1 responses, and enhanced nitric oxide production
45. Upregulation of tubular epithelial interleukin-12 in autoimmune MRL-Fas (lpr) mice with renal injury