The β-thromboglobulins and platelet factor 4: Blood platelet-derived CXC chemokines with divergent roles in early neutrophil regulation

Journal of Leukocyte Biology

Volumn 67, Issue 4, 2000, Pages 471-478

  Brandt, E ^a   Petersen, F ^a   Ludwig, A ^a   Ehlert, J E ^a   Bock, L ^a   Flad, H D ^a  

^a RESEARCH CENTER BORSTEL   (Germany)

Author keywords

Adhesion; Chemotaxis; Desensitization; Inflammation; Proteoglycan; Receptors

Indexed keywords

ALPHA CHEMOKINE; BETA THROMBOGLOBULIN; INTERLEUKIN 8; THROMBOCYTE FACTOR 4;

CHEMOTAXIS; HUMAN; LEUKOCYTE ACTIVATION; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROCESSING; REGULATORY MECHANISM; REVIEW;

EID: 0033840734     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1002/jlb.67.4.471     Document Type: Review

References (38)

1. Chemokines
2. Chemokines - Chemotactic cytokines that mediate inflammation
3. Recent advances in chemokines and chemokine receptors
4. Structural requirements of platelet chemokines for neutrophil activation
5. 2-terminal residues and evidence for uncoupling of neutrophil chemotaxis, exocytosis, and receptor binding activities
6. Platelet factor 4 binds to interleukin 8 receptors and activates neutrophils When its N terminus is modified with Glu-Leu-Arg
7. Platelet factor 4: Production, structure, and physiologic and immunologic action
8. Cloning of cDNA coding for connective tissue activating peptide III from a human platelet-derived lambda gt11 expression library
9. Chemokine and chemokine receptor mRNA expression in human platelets
10. Characterization of the human beta-thromboglobulin gene. Comparison with the gene for platelet factor 4
11. Leukocyte-derived growth factor links the PDGF and CXC chemokine families of peptides
12. Cell type specific expression of members of the IL-8/NAP-1 gene family
13. Immunohistochemical identification of mast cells in paraffin- and epon-embedded tissues using platelet factor 4
14. The immunoelectronmicroscopic localization of human platelet factor 4 in tissue mast cells
15. Studies of human platelet alpha-granule release in vivo
16. Occurrence of platelet basic protein, a precursor of low affinity platelet factor 4 and β-thromboglobulin, in human platelets and megakaryocytes
17. Characterization of human platelet basic protein, a precursor form of low-affinity platelet factor 4 and β-thromboglobulin
18. The isolation and characterization of platelet specific β-globulin and the detection of an anti-urokinase and anti plasmin released from thrombin-aggregated and washed human platelets
19. Complete covalent structure of human beta-thromboglobulin
20. Characterization of a platelet derived factor modulating phagocyte functions and cooperating with interleukin 1
21. Generation of the neutrophil-activating peptide NAP-2 from platelet basic protein or connective tissue-activating peptide III through monocyte proteases
22. Neutrophils can generate their activator neutrophil-activating peptide 2 by proteolytic cleavage of platelet-derived connective tissue-activating peptide III
23. Connective tissue-activating peptide III desensitizes chemokine receptors on neutrophils. Requirement for proteolytic formation of the neutrophil-activating peptide 2
24. A novel cleavage product of β-thromboglobulin formed in cultures of stimulated mononuclear cells activates neutrophils
25. Effects of the neutrophil-activating peptide NAP-2, platelet basic protein, connective tissue-activating peptide III, and platelet factor 4 on human neutrophils
26. 2+]i changes and respiratory burst in human neutrophils and monocytes induced by NAP-1/interleukin-8, NAP-2, and gro/MGSA
27. Neutrophil-activating peptides NAP-2 and IL-8 bind to the same sites on neutrophils but interact in different ways. Discrepancies in binding affinities, receptor densities, and biologic effects
28. The CXC-chemokine neutrophil-activating peptide-2 induces two distinct optima of neutrophil chemotaxis by differential interaction with interleukin-8 receptors CXCR-1 and CXCR-2
29. A novel molecular variant of the neutrophil-activating peptide NAP-2 with enhanced biological activity is truncated at the C-terminus: Identification by antibodies with defined epitope specificity
30. Limited and defined truncation at the C-terminus enhances receptor binding and degranulation activity of the neutrophil-activating peptide 2 (NAP-2)
31. Novel C-terminally truncated isoforms of the CXC-chemokine β-thromboglobulin and their impact on neutrophil functions
32. The crystal structure of recombinant human neutrophil-activating peptide-2 (M6L) at 1.9-A resolution
33. Secondary structure of neutrophil-activating peptide-2 determined by 1H-nuclear magnetic resonance spectroscopy
34. Amino acid sequence of human platelet factor 4
35. TNF-alpha renders human neutrophils responsive to platelet factor 4. Comparison of PF-4 and IL-8 reveals different activity profiles of the two chemokines
36. Platelet factor 4-induced neutrophil-endothelial cell interaction: Involvement of mechanisms and functional consequences different from those elicited by IL-8
37. A chondroitin sulfate proteoglycan functions as a receptor for platelet factor 4 on human neutrophils
38. Characterization of a neutrophil cell surface glycosaminoglycan that mediates binding of platelet factor 4