Keratinocyte growth factor prevents ventilator-induced lung injury in an ex vivo rat model

American Journal of Respiratory and Critical Care Medicine

Volumn 162, Issue 3 I, 2000, Pages 1081-1086

  Welsh, David A ^a   Summer, Warren R ^a   Dobard, Elizabeth P ^a   Nelson, Steve ^a   Mason, Carol M ^a  

^a LOUISIANA STATE UNIV MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLUORESCEIN ISOTHIOCYANATE DEXTRAN; KERATINOCYTE GROWTH FACTOR;

AIRWAY DYNAMICS; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ARTIFICIAL VENTILATION; CELL HYPERPLASIA; CONTROLLED STUDY; CYTOKINE PRODUCTION; HISTOPATHOLOGY; LUNG COMPLIANCE; LUNG EDEMA; LUNG INJURY; MALE; MEMBRANE PERMEABILITY; NONHUMAN; PRIORITY JOURNAL; RAT; TIDAL VOLUME;

EID: 0033834342     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.162.3.9908099     Document Type: Article

References (40)

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10. Purification and characterization of a newly identified growth factor specific for epithelial cells
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12. Keratinocyte growth factor is a growth factor for type II pneumocytes in vivo
13. Keratinocyte growth factor attenuates lung leak induced by α-naphthylthiourea in rats
14. KGF prevents hydrogen peroxide-induced increases in airway epithelial cell permeability
15. Keratinocyte growth factor reduces lung damage due to acid instillation in rats
16. Keratinocyte growth factor increases transalveolar sodium reabsorption in normal and injured rat lungs
17. Fluorescein-labeled dextran concentration is increased in BAL fluid after ANTU-induced edema in rats
18. Na-K-ATPase expression in alveolar epithelial cells: Upregulation of active ion transport by KGF
19. Alveolar epithelial fluid transport can be up-regulated simultaneously in rats by two different mechanisms
20. Keratinocyte growth factor modulates alveolar epithelial cell phenotype in vitro: Expression of aquaporin 5
21. Intervenous keratinocyte growth factor protects against experimental pulmonary injury
22. Pre- and posttreatment with keratinocyte growth factor protects against radiation-induced permeability increases in airway epithelial cell monolayers
23. Keratinocyte growth factor (KGF) reduces alveolar epithelial susceptibility to in vitro deformation
24. Keratinocyte growth factor-2 accelerates wound healing in incisional wounds
25. Double intratracheal instillation of keratinocyte growth factor prevents bleomycin-induced lung fibrosis in rats
26. Regulation of the expression of stromelysin-2 by growth factors in keratinocytes: Implications for normal and impaired wound healing
27. Cell type-specific inhibition of keratinocyte collagenase-1 expression by basic fibroblast growth factor and keratinocyte growth factor
28. Stimulation of collagenase (matrix metalloproteinase-1) synthesis in histiotypic epithelial cell culture by heparin is enhanced by keratinocyte growth factor
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30. Differential permeability of endothelial and epithelial barriers to albumin flux
31. Regulation of vascular endothelial growth factor expression in cultured keratinocytes
32. Keratinocyte growth factor induces angiogenesis and protects endothelial barrier function
33. Synergistic ineraction between alveolar flooding and distension during mechanical ventilation
34. Keratinocyte growth factor increases surfactant pool sizes in premature rabbits
35. Keratinocyte growth factor increases mRNAs for SP-A and SP-B in adult rat alveolar type II cells in culture
36. Surfactant protein and CC-10 expression in acute lung injury and in response to keratinocyte growth factor
37. Surfactant dysfunction makes lungs vulnerable to repetitive collapse and reexpansion
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39. Hemodynamic consequences of mechanical ventilation