Hemodynamic consequences of mechanical ventilation

Clinical Pulmonary Medicine

Volumn 6, Issue 1, 1999, Pages 52-65

  Welsh, David A ^a   Summer, Warren R ^a   DeBoisblanc, Bennett ^a   Thomas, Dwayne ^a,b  

^a LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b LSU Section of Pulmonary/Critical Can Medicine   (United States)

Author keywords

Cardiac output; Hemodynamics; Mechanical ventilation; Positive end expiratory pressure

Indexed keywords

AIRWAY OBSTRUCTION; ARTERIAL PRESSURE; ARTIFICIAL VENTILATION; CARDIOVASCULAR PERFORMANCE; CARDIOVASCULAR RESPONSE; CRITICAL ILLNESS; HEART AFTERLOAD; HEART CONTRACTION; HEART FAILURE; HEART OUTPUT; HEART PRELOAD; HEART RATE; HEMODYNAMICS; HUMAN; PATHOPHYSIOLOGY; POSITIVE END EXPIRATORY PRESSURE; RESPIRATORY DISTRESS SYNDROME; REVIEW; SYSTEMIC VASCULAR RESISTANCE; VENOUS RETURN;

EID: 0032994728     PISSN: 10680640     EISSN: None     Source Type: Journal    
DOI: 10.1097/00045413-199901000-00006     Document Type: Review

References (107)

1. Pinsky MR. Determinants of pulmonary arterial flow variation during respiration. J Appl Physiol 1984;56:1237-45.
2. Santamore WP, Heckman JL, Bove AA. Cardiovascular changes from expiration to inspiration during IPPV. Am J Physiol 1983;245: H307-H312.
3. Morgan BC, Martin WE, Hornbein TF, Crawford EW, Guntheroth WG. Hemodynamic effects of intermittent positive pressure respiration. Anesthesiology 1966;27:584-90.
4. Qvist J, Pontoppidan H, Wilson RS, Lowenstein E, Laver MB. Hemodynamic responses to mechanical ventilation with PEEP: the effect of hypervolemia. Anesthesiology 1975; 42:45-55.
5. Leithner C, Podolsky A, Globits S, et al. Magnetic resonance imaging of the heart during positive end-expiratory pressure ventilation in normal subjects. Crit Care Med 1994;22: 426-32.
6. Huemer G, Kolev N, Kurz A, Zimpfer M. Influence of positive end-expiratory pressure on right and left ventricular performance assessed by doppler two-dimensional echocardiography. Chest 1994;106:67-73.
7. Terai C, Uenishi M, Sugimoto H, Shimazu T, Yoshioka T, Sugimoto T. Transesophageal echocardiographic dimensional analysis of four cardiac chambers during positive end-expiratory pressure. Anesthesiology 1985;63: 640-6.
8. Scharf A, Caldini P, Ingram R Jr. Cardiovascular effects of increasing airway pressure in the dog. Am J Physiol 1977;232:H35-H43.
9. Cassidy S, Eschenbacher W, Robertson C Jr, Nixon J, Blomqvist G, Johnson R Jr. Cardiovascular effects of positive-pressure ventilation in normal subjects. J Appl Physiol 1979; 47:453-61.
10. Takata M, Robotham J. Effects of inspiratory diaphragmatic descent on inferior vena caval venous return. J Appl Physiol 1992;72:597-607.
11. Scharf S, Ingram R. Influence of abdominal pressure and sympathetic vasoconstriction on the cardiovascular response to positive end-expiratory pressure. Am Rev Respir Dis 1977;116:661-70.
12. Vatner SF, Rutherford JD. Interaction of carotid chemoreceptor and pulmonary inflation reflexes in circulatory regulation in conscious dogs. Fed Proc 1981;40:2188-93.
13. Shepherd JT. The lungs as receptor sites for cardiovascular regulation. Circulation 1981; 63:1-10.
14. Frass M, Watschinger B, Traindl O, et al. Atrial natriuretic peptide release in response to different positive end-expiratory pressure levels. Crit Care Med 1993;21:343-7.
15. Shirakami G, Magaribuchi T, Shingu K, et al. Positive end-expiratory pressure ventilation decreases plasma atrial and brain natriuretic peptide levels in humans. Anesth Analg 1993;77:1116-21.
16. Brower R, Wise RA, Hassapoyannes C, Bromberger-Barnea B, Permutt S. Effect of lung inflation on lung blood volume and pulmonary venous flow. J Appl Physiol 1985; 58:954-63.
17. Laks M, Garner D, Morady F, Swan H. Hemodynamics in the conscious dog during progressive pulmonary arterial occlusion. Am J Physiol 1972;222:578-82.
18. Marini JJ, O'Quin R, Culver BH, Butler J. Estimation of transmural cardiac pressures during ventilation with PEEP. J Appl Physiol 1982;53:384-91.
19. Bell R, Robotham J, Badke F, Little W, Kindred M. Left ventricular geometry during intermittent positive pressure ventilation in dogs. J Crit Care 1987;4:230-44.
20. Cassidy S, Mitchell J, Johnson R Jr. Dimensional analysis of right and left ventricles during positive-pressure ventilation in dogs. Am J Physiol 1982;242:H549-H556.
21. Scharf S. LV shape changes with IPPV. J Crit Care 1987;4:227-9.
22. Cassidy S, Robertson C Jr, Pierce A, Johnson R Jr. Cardiovascular effects of positive end-expiratory pressure in dogs. J Appl Physiol 1978;44:743-50.
23. Fewell J, Abendschein D, Carlson C, Rapaport E, Murray J. Mechanism of decreased right and left ventricular end-diastolic volumes during continuous positive-pressure ventilation in dogs. Circ Res 1980;47:467-72.
24. Whittenberger J, McGregor M, Berglund E, Borst H. Influence of state of inflation of the lung on pulmonary vascular resistance. J Appl Physiol 1960;15:878-82.
25. Hakim TS, Michel RP, Chang HK. Effect of lung inflation on pulmonary vascular resistance by arterial and venous occlusion. J Appl Physiol 1982;53:1110-5.
26. Scharf S, Brown R. Influence of the right ventricle on canine left ventricular function with PEEP. J Appl Physiol 1982;52:254-9.
27. Culver B, Marini J, Butler J. Lung volume and pleural pressure effects on ventricular function. J Appl Physiol 1981;50:630-5.
28. Biondi JW, Schulman DS, Soufer R, et al. The effect of incremental positive end-expiratory pressure on right ventricular hemodynamics and ejection fraction. Anesth Analg 1988;67: 144-51.
29. Schulman D, Biondi J, Matthay R, Barash P, Zaret B, Soufer R. Effect of positive end-expiratory pressure on right ventricular performance. Am J Med 1988;84:57-67.
30. Buda AJ, Pinsky MR, Ingels NB Jr, Daughters GT 2d, Stinson EB, Alderman EL. Effect of intrathoracic pressure on left ventricular performance. N Engl J Med 1979;301:453-9.
31. Scharf SM, Saunders RBN, Green LH, Ingram RH Jr. Changes in canine left ventricular size and configuration with positive end-expiratory pressure. Circ Res 1979;44:672-8.
32. Brinker JA, Weiss JL, Lappe DL, et al. Left-ward septal displacement during right ventricular loading in man. Circulation 1980;61: 626-33.
33. Taylor RR, Covell JW, Sonnenblick EH, Ross J Jr. Dependence of ventricular distensibility on filling of the opposite ventricle. Am J Physiol 1967;213:711-8.
34. Olsen C, Tyson G, Maier G, Spratt J, Davis J, Rankin J. Dynamic ventricular interaction in the conscious dog. Circ Res 1983;52:85-104.
35. Robotham JL, Lixfeld W, Holland L, et al. The effects of positive end-expiratory pressure on right and left ventricular performance. Am Rev Respir Dis 1980;121:677-83.
36. Marini JJ, Culver BH, Butler J. Effect of positive end-expiratory pressure on canine ventricular function curves. J Appl Physiol 1981; 51:1367-74.
37. Summer WR, Permutt S, Sagawa K, Shoukas AA, Bromberger-Barnea B. Effects of spontaneous respirations on canine left ventricular function. Circ Res 1979;45:719-28.
38. Pinsky MR, Summer WR, Wise RA, Permutt S, Bromberger-Barnea B. Augmentation of cardiac function by elevation of intrathoracic pressure. J Appl Physiol 1983;54:950-5.
39. Pinsky MR, Matuschak GM, Klain M. Determinants of cardiac augmentation by elevations in intrathoracic pressure. J Appl Physiol 1985;58:1189-98.
40. Fessler HE, Brower RG, Wise RA, Permutt S. Mechanism of reduced LV afterload by systolic and diastolic positive pleural pressure. J Appl Physiol 1988;65:1244-50.
41. Fessler HE, Browler RG, Wise R, Permutt S. Positive pleural pressure decreases coronary perfusion. Am J Physiol 1990;258:H814-H820.
42. Tittley JG, Fremes SE, Weisel RD, et al. Hemodynamic and myocardial metabolic consequences of PEEP. Chest 1985;88:496-502.
43. Schulman DS, Biondi JW, Zohgbi S, Zaret BL, Soufer R. Coronary flow limits right ventricular performance during positive end-expiratory pressure. Am Rev Respir Dis 1990; 141:1531-7.
44. Schulman DS, Biondi JW, Zohgbi S, Cecchetti A, Zaret BL, Soufer R. Left ventricular diastolic function during positive end-expiratory pressure. Am Rev Respir Dis 1992;145: 515-21.
45. Glick G, Wechsler A, Epstein S. Reflex cardiovascular depression produced by stimulation of pulmonary stretch receptors in the dog. J Clin Invest 1969;48:467-73.
46. Ashton J, Cassidy S. Reflex depression of cardiovascular function during lung inflation. J Appl Physiol 1985;58:137-45.
47. Greenwood P, Hainsworth R, Karim F, Morrison G, Sofola O. Reflex inotropic responses of the heart from lung inflation in anaesthetized dogs. Pflugers Arch 1980;386:199-205.
48. Stinnett H. Altered cardiovascular reflex responses during positive pressure breathing. Fed Proc 1981;40:2181-7.
49. Vatner S, Rutherford J. Control of the myocardial contractile state by carotid chemoand baroreceptor and pulmonary inflation reflexes in conscious dogs. J Clin Invest 1978; 63:1593-601.
50. Manny J, Grindlinger G, Mathe AA, Hecht-man HB. Positive end-expiratory pressure, lung stretch, and decreased myocardial contractility. Surgery 1978;84:127-33.
51. Patten M, Liebman P, Hechtman H. Humorally mediated decreases in cardiac output associated with positive end expiratory pressure. Microvasc Res 1977;13:137-9.
52. Dunham BM, Grindlinger GA, Utsunomiya T, Krausz MM, Hechtman HB, Shepro D. Role of prostaglandins in positive end-expiratory pressure induced negative inotropism. Am J Physiol 1981;241:H783-H788.
53. Prewitt RM, Wood LDH. Effect of positive end-expiratory pressure on ventricular function in dogs. Am J Physiol 1979;5:H534-H544.
54. Macefield V, Wallin B. Modulation of muscle sympathetic activity during spontaneous and artificial ventilation and apnoea in humans. J Auton Nerv Syst 1995;53:137-47.
55. Marini JJ, Culver BH, Butler J. Compensatory circulatory response to positive end-expiratory pressure [abstract]. Am Rev Respir Dis 1983;127:311.
56. De Burgh Daly M, Hazzledine JL, Ungar A. The reflex effects of alterations in lung volume on systemic vascular resistance in the dog. J Physiol (Lond) 1967;188:331-51.
57. Lloyd TC Jr. Reflex effects of lung inflation and inhalation of halothane, ether, and ammonia. Am J Physiol 1978;45:212-8.
58. Ott NT, Shepherd JT. Vasodepressor reflex from lung inflation in the rabbit. Am J Physiol 1971;221:889-95.
59. Bernard GR, Artigas A, Brigham KL, et al. The American-European consensus conference on ARDS: definitions, mechanisms, relevant outcomes, and clinical trial coordination. Am J Respir Crit Care Med 1994;149: 818-24.
60. Kollef MH, Schuster DP. The acute respiratory distress syndrome. N Engl J Med 1995; 332:27-37.
61. Pinsky MR, Guimond J-G. The effects of positive end-expiratory pressure on heart-lung interactions. J Crit Care 1991;6:1-11.
62. Ellman H, Dembin H. Lack of adverse hemodynamic effects of PEEP in patients with acute respiratory failure. Crit Care Med 1982; 10:706-11.
63. Jardin F, Genevray B, Brun-Ney D, Bourdarias J-P. Influences of lung and chest wall compliances on transmission of airway pressure to the pleural space in critically ill patients. Chest 1985;88:653-8.
64. Benito S, Lemaire F. Pulmonary pressure-volume relationship in acute respiratory distress syndrome in adults: role of positive end expiratory pressure. J Crit Care 1990;5:27-34.
65. Romand JA, Shi W, Pinsky MK. Cardiopulmonary effects of positive pressure ventilation during acute lung injury. Chest 1995;108:1041-8.
66. Scharf SM, Ingram RH. Effects of decreasing lung compliance with oleic acid on the cardiovascular response to PEEP. Am J Physiol 1977;233:H635-H641.
67. Cabrera MR, Nakamura GE, Montague DA, Cole RP. Effect of airway pressure on pericardial pressure. Am Rev Respir Dis 1989; 140:659-67.
68. Mang H, Kacmarek RM, Ritz K, Wilson RS, Kimball WP. Cardiorespiratory effects of volume-and pressure-controlled ventilation at various I/E ratios in an acute lung injury model. Am J Respir Crit Care Med 1995;151:731-6.
69. Venus B, Cohen LE, Smith RA. Hemodynamics and intrathoracic pressure transmission during controlled mechanical ventilation and positive end-expiratory pressure in normal and low compliant lungs. Crit Care Med 1988;16:686-90.
70. Mundie TG, Easa D, Finn KC, Stevens EL, Hashiro G, Balaraman V. Effect of baseline lung compliance on the subsequent response to positive end-expiratory pressure in ventilated piglets with normal lungs. Crit Care Med 1994;22:1631-8.
71. Gattinoni L, Pesenti A, Bombine M, et al. Relationships between lung computed tomographic density, gas exchange, and PEEP in acute respiratory failure. Anesthesiology 1988;69:824-32.
72. Gattinoni L, Pesenti A, Avalli L, Rossi F, Bombino M. Pressure-volume curve of total respiratory system in acute respiratory failure. Am Rev Respir Dis 1987;136:730-6.
73. Cereda M, Foti G, Musch G, Sparacino ME, Pesenti A. Positive end-expiratory pressure prevents the loss of respiratory compliance during low tidal volume ventilation in acute lung injury patients. Chest 1996;109:480-5.
74. Dhainaut J, Bricard C, Monsalier F, et al. Left ventricular contractility using isovolumic phase indices during PEEP in ARDS patients. Crit Care Med 1982;10:631-5.
75. Dhainaut JF, Devaux JY, Monsallier JF, Brunet F, Villemant D, Huyghebaert MF. Mechanisms of decreased left ventricular preload during continuous positive pressure ventilation in ARDS. Chest 1986;90:74-80.
76. Jardin F, Farcot J-C, Boisante L, Curien K Margairaz A, Bourdarias J-P. Influence of positive end-expiratory pressure on left ventricular performance. N Engl J Med 1981;304: 387-92.
77. Potkin RT, Hudson LD, Weaver LJ, Trobaugh G. Effect of positive end-expiratory pressure on right and left ventricular function in patients with the adult respiratory distress syndrome. Am Rev Respir Dis 1987;135:307-11.
78. Ralph DD, Robertson HT, Weaver LJ, Hlastala MP, Carrico CJ, Hudson LD. Distribution of ventilation and perfusion during positive end-expiratory pressure in the adult respiratory distress syndrome. Am Rev Respir Dis 1985;131:54-60.
79. Ranieri VM, Mascia L, Fiore T, Bruno F, Brienza A, Giuliani R. Cardiorespiratory etfects of positive end-expiratory pressure during progressive tidal volume reduction (permissive hypercapnia) in patients with acute respiratory distress syndrome. Anesthesiology 1995;83:710-20.
80. Ledwigs U, Klingstedt C, Baehrendtz S, Wegenius G, Hedenstierna G. Volume-controlled inverse ratio ventilation in oleic acid induced lung injury: effects on gas exchange, hemodynamics, and computed tomographic lung density. Chest 1995;108:804-9.
81. Zobel G, Dacar D, Rodl S. Hemodynamic effects of different modes of mechanical ventilation in acute cardiac and pulmonary failure: an experimental study. Crit Care Med 1994;22:1624-30.
82. Laubscher B, van Melle G, Fawer CL, Sekarski N, Calame A. Haemodynamic changes during high frequency oscillation for respiratory distress syndrome. Arch Dis Child Fetal Neonatal Ed 1996;74:F172-F176.
83. Macklem PT. Hyperinflation. Am Rev Respir Dis 1984;129:1-2.
84. Summer WR. Status asthmaticus. Chest 1985; 87(1 Suppl)S:87S-94S.
85. Blaustein AS, Risser TA, Weiss JW, Parker JA, Holman BL, McFadden ER. Mechanisms of pulsus paradoxus during resistive respiratory loading and asthma. J Am Coll Cardiol 1986;8:529-36.
86. Jardin F, Dubourg O, Margairaz A, Bourdarias J-P. Inspiratory impairment in right ventricular performance during acute asthma. Chest 1987;92:789-95.
87. Williams TJ, Tuxen DV, Scheinkestel CD, Czarny D, Bowes G. Risk factors for morbidity in mechanically ventilated patients with acute severe asthma. Am Rev Respir Dis 1992;146:607-15.
88. Marini JJ. Should PEEP be used in airflow obstruction? Am Rev Respir Dis 1989;140:1-3.
89. Pepe PE, Marini JJ. Occult positive end-expiratory pressure in mechanically ventilated patients with airflow obstruction. Am Rev Respir Dis 1982;126:166-70.
90. Singer M, Vermaat J, Hall G, Latter G, Patel M. Hemodynamic effects of manual hyperinflation in critically ill mechanically ventilated patients. Chest 1994;106:1182-7.
91. Smith TC, Marini JJ. Impact of PEEP on lung mechanics and work of breathing in severe airflow obstruction. J Appl Physiol 1988;65: 1488-99.
92. Tuxen DV. Detrimental effects of positive end-expiratory pressure during controlled mechanical ventilation of patients with severe airflow obstruction. Am Rev Respir Dis 1989;140:5-9.
93. Petrof BJ, Legare M, Goldberg P, Milic-Emili J, Gottfried SB. Continuous positive airway pressure reduces work of breathing and dyspnea during weaning from mechanical ventilation in severe chronic obstructive pulmonary disease. Am Rev Respir Dis 1990;141: 281-9.
94. A/Q mismatching in ventilated patients with chronic airflow obstruction. Am J Respir Crit Care Med 1994;149:1077-84.
95. Baigorri F, Monte AD, Blanch L, et al. Hemodynamic responses to external counterbalancing of auto-positive end-expiratory pressure in mechanically ventilated patients with chronic obstructive pulmonary disease. Crit Care Med 1994;22:1782-91.
96. Ranieri VM, Giuliani R, Cinnella G, et al. Physiologic effects of positive end-expiratory pressure in patients with chronic obstructive pulmonary disease during acute ventilatory failure and controlled mechanical ventilation. Am Rev Respir Dis 1993;147:5-13.
97. Abel JG, Salerno TA, Panos A, et al. Cardiovascular effects of positive pressure ventilation in humans. Ann Thorac Surg 1987;43:198-206.
98. Scharf S, Chen L, Slamosvitz D, Rao F. Effects of continuous positive airway pressure on cardiac output and plasma norepinephrine in sedated pigs. J Crit Care 1996;11:57-64.
99. Beach T, Millen E, Grenvik A. Hemodynamic response to discontinuance of mechanical ventilation. Crit Care Med 1973;1:85-90.
100. Calvin JE, Driedger AA, Sibbald WJ. Positive end-expiratory pressure (PEEP) does not depress left ventricular function in patients with pulmonary edema. Am Rev Respir Dis 1981;124:121-8.
101. Schuster S, Erbel R, Weilemann LS, et al. Hemodynamics during PEEP ventilation in patients with severe left ventricular failure studied by transcsophageal echocardiography. Chest 1990;97:1181-9.
102. Rasanen J, Vaisanen IT, Heikkila J, Nikki P. Acute myocardial infarction complicated by left ventricular dysfunction and respiratory failure. Chest 1985;87:158-62.
103. Grace M, Greenbaum D. Cardiac performance in response to PEEP in patients with cardiac dysfunction. Crit Care Med 1982;10: 358-60.
104. Vilres N, Sillye G, Aubier M, Rassidakis A, Roussos C. Regional blood flow distribution in dog during induced hypotension and low cardiac output. J Clin Invest 1983;72:935-47.
105. Kasanen J, Nikki P, Heiddila J. Acute myocardial infarction complicated by respiratory failure. Chest 1984;85:21-8.
106. Fewell JE, Abendschein DR, Carlson CJ, Rapaport E, Murray JF. Continuous positive-pressure ventilation does not alter ventricular pressure-volume relationship. Am J Physiol 1981;240:H821-H826.
107. Morgan BC, Crawford EW, Guntheroth WG. The hemodynamic effects of changes in blood volume during intermittent positive-pressure ventilation. Anesthesiology 1969;30:297-305.