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Volumn 23, Issue 4, 2000, Pages 352-357

Adaptation and clinical evaluation of a homogenous enzyme multiplied immunoassay technique (EMIT) for drug monitoring of a methotrexate-albumin conjugate (MTX-HSA) in humans

Author keywords

7 Hydroxymethotrexate; Albumin conjugates; Drug carriers; EMIT; Methotrexate pharmacology

Indexed keywords

7 HYDROXYMETHOTREXATE; ALBUMIN CONJUGATE; METHOTREXATE;

EID: 0033832206     PISSN: 0378584X     EISSN: None     Source Type: Journal    
DOI: 10.1159/000027169     Document Type: Article
Times cited : (3)

References (27)
  • 2
    • 0001004859 scopus 로고
    • Five years experience with the chemotherapy of metastatic choriocarcinoma and related trophoblastic tumors in women
    • Hertz R, Lewis J, Lipsett MB: Five years experience with the chemotherapy of metastatic choriocarcinoma and related trophoblastic tumors in women. Am J Obstet Gynecol 1961;82:631-637.
    • (1961) Am J Obstet Gynecol , vol.82 , pp. 631-637
    • Hertz, R.1    Lewis, J.2    Lipsett, M.B.3
  • 3
    • 0027351189 scopus 로고
    • Ode to methotrexate
    • Bertino JR: Ode to methotrexate. J Clin Oncol 1993; 11:5-14.
    • (1993) J Clin Oncol , vol.11 , pp. 5-14
    • Bertino, J.R.1
  • 4
    • 0031825771 scopus 로고    scopus 로고
    • New antimetabolites in cancer chemotherapy and their clinical impact
    • Kaye SB: New antimetabolites in cancer chemotherapy and their clinical impact. Br J Cancer 1998; 78(suppl 3):1-7.
    • (1998) Br J Cancer , vol.78 , Issue.3 SUPPL. , pp. 1-7
    • Kaye, S.B.1
  • 5
    • 0000543798 scopus 로고
    • Anticancer drugs
    • de Vita VT, Hellman S, Rosenberg SA (eds): Philadelphia, Lippincott
    • Chabner BA: Anticancer drugs; in de Vita VT, Hellman S, Rosenberg SA (eds): Cancer: Principles and Practice of Oncology. Philadelphia, Lippincott, 1993, pp 325-417.
    • (1993) Cancer: Principles and Practice of Oncology , pp. 325-417
    • Chabner, B.A.1
  • 7
    • 0030872642 scopus 로고    scopus 로고
    • On the growth rates of human malignant tumors: Implications for medical decision making
    • Friberg S, Mattson S: On the growth rates of human malignant tumors: Implications for medical decision making. J Surg Oncol 1997;65:284-297.
    • (1997) J Surg Oncol , vol.65 , pp. 284-297
    • Friberg, S.1    Mattson, S.2
  • 11
    • 0026092328 scopus 로고
    • Identification of tissue sites for increased albumin degradation in sarcoma-bearing mice
    • Andersson C, Iresjo BM, Lundholm K: Identification of tissue sites for increased albumin degradation in sarcoma-bearing mice. J Surg Res 1991;50:156-162.
    • (1991) J Surg Res , vol.50 , pp. 156-162
    • Andersson, C.1    Iresjo, B.M.2    Lundholm, K.3
  • 17
    • 0033112951 scopus 로고    scopus 로고
    • Methotrexate-albumin conjugate causes tumor growth delay in Dunning R3327 Hi prostate cancer bearing rats
    • Stehle G, Wunder A, Schrenk HH, Hartung G, Heene DL, Sinn H: Methotrexate-albumin conjugate causes tumor growth delay in Dunning R3327 Hi prostate cancer bearing rats. Anticancer Drugs 1999;10:405-411.
    • (1999) Anticancer Drugs , vol.10 , pp. 405-411
    • Stehle, G.1    Wunder, A.2    Schrenk, H.H.3    Hartung, G.4    Heene, D.L.5    Sinn, H.6
  • 18
    • 0008901910 scopus 로고    scopus 로고
    • In vivo activity of a methotrexate-albumin conjugate (MTX-HSA) in human tumor xenografts
    • abstract
    • Fiebig HH, Roth T, Hartung G, Sinn H, Stehle G: In vivo activity of a methotrexate-albumin conjugate (MTX-HSA) in human tumor xenografts. Eur J Cancer 1997;33(suppl 8):S174(abstract).
    • (1997) Eur J Cancer , vol.33 , Issue.8 SUPPL.
    • Fiebig, H.H.1    Roth, T.2    Hartung, G.3    Sinn, H.4    Stehle, G.5
  • 19
    • 84867109094 scopus 로고    scopus 로고
    • Drug monitoring and pharmacokinetics of a methotrexate-albumin conjugate (MTX-HSA) in cancer patients with long term remission
    • abstract
    • Hartung G, Stehle G, Heeger S, Kranzle M, Wunder A, Bertsch T, Köpke J, Spacek S, Sinn H, Queißer W: Drug monitoring and pharmacokinetics of a methotrexate-albumin conjugate (MTX-HSA) in cancer patients with long term remission. Eur J Cancer 1999;35(suppl 4):1188(abstract).
    • (1999) Eur J Cancer , vol.35 , Issue.4 SUPPL. , pp. 1188
    • Hartung, G.1    Stehle, G.2    Heeger, S.3    Kranzle, M.4    Wunder, A.5    Bertsch, T.6    Köpke, J.7    Spacek, S.8    Sinn, H.9    Queißer, W.10
  • 20
    • 84944431299 scopus 로고
    • Determination of methotrexate in serum by a rapid, fully mechanized enzyme immunoassay (EMIT)
    • Oellerich M, Engelhardt P, Schaadt M, Diehl V: Determination of methotrexate in serum by a rapid, fully mechanized enzyme immunoassay (EMIT). J Clin Chem Clin Biochem 1980;18:169-174.
    • (1980) J Clin Chem Clin Biochem , vol.18 , pp. 169-174
    • Oellerich, M.1    Engelhardt, P.2    Schaadt, M.3    Diehl, V.4
  • 21
    • 0017715318 scopus 로고
    • A rapid, sensitive and specific radioimmunoassay for methotrexate
    • Paxton JW, Rosw ell FJ: A rapid, sensitive and specific radioimmunoassay for methotrexate. Clin Chim Acta 1977;80:563-572.
    • (1977) Clin Chim Acta , vol.80 , pp. 563-572
    • Paxton, J.W.1    Roswell, F.J.2
  • 22
    • 0017752168 scopus 로고
    • Methotrexate assay by enzymatic inhibition, with use of the centrifugal analyzer
    • Finley PR, Williams RJ: Methotrexate assay by enzymatic inhibition, with use of the centrifugal analyzer. Clin Chem 1977;23:2139-2141.
    • (1977) Clin Chem , vol.23 , pp. 2139-2141
    • Finley, P.R.1    Williams, R.J.2
  • 23
    • 0019194439 scopus 로고
    • Methotrexat-Nachweis im menschlichen Serum - Vergleich zwischen einer enzymatischen und einer enzymimmunologischen Methode
    • Schalhora A, Wilmanns W, Stupp-Poutot G: Methotrexat-Nachweis im menschlichen Serum - Vergleich zwischen einer enzymatischen und einer enzymimmunologischen Methode. Onkologie 1980;4:193-196.
    • (1980) Onkologie , vol.4 , pp. 193-196
    • Schalhora, A.1    Wilmanns, W.2    Stupp-Poutot, G.3
  • 24
    • 0017743648 scopus 로고
    • Analysis of methotrexate in human plasma by high performance liquid chromatography with fluorescence detection
    • Nelson JA, Harris BA, Decker WJ, Farquhar P: Analysis of methotrexate in human plasma by high performance liquid chromatography with fluorescence detection. Cancer Res 1977;37:3970-3973.
    • (1977) Cancer Res , vol.37 , pp. 3970-3973
    • Nelson, J.A.1    Harris, B.A.2    Decker, W.J.3    Farquhar, P.4
  • 25
    • 0029804616 scopus 로고    scopus 로고
    • External quality assessment of Syva Emit and Abbott TDx II assays for methotrexate in serum
    • Wilson JF, Tsanaclis LM, Barnett K: External quality assessment of Syva Emit and Abbott TDx II assays for methotrexate in serum. Ther Drug Monit 1996; 18:721-723.
    • (1996) Ther Drug Monit , vol.18 , pp. 721-723
    • Wilson, J.F.1    Tsanaclis, L.M.2    Barnett, K.3
  • 26
    • 0031581915 scopus 로고    scopus 로고
    • Determination of methotrexate and its metabolite 7-hydroxymethotrexate by direct injection of human plasma into a column-switching liquid chromatographic system using post-column photochemical reaction with fluorimetric detection
    • Yu Z, Westerlund D, Boos K-S: Determination of methotrexate and its metabolite 7-hydroxymethotrexate by direct injection of human plasma into a column-switching liquid chromatographic system using post-column photochemical reaction with fluorimetric detection. J Chromatography B 1997;689:379-386.
    • (1997) J Chromatography B , vol.689 , pp. 379-386
    • Yu, Z.1    Westerlund, D.2    Boos, K.-S.3
  • 27
    • 84867110744 scopus 로고    scopus 로고
    • Keller H: Klinisch-chemische Labordiagnostik für die Praxis Stuttgart, Thieme 1991, pp 73
    • Keller H: Klinisch-chemische Labordiagnostik für die Praxis Stuttgart, Thieme 1991, pp 73.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.