메뉴 건너뛰기




Volumn 10, Issue 4, 1999, Pages 405-411

Methotrexate-albumin conjugate causes tumor growth delay in Dunning R3327 HI prostate cancer-bearing rats

Author keywords

Albumins; Copenhagen rats; Drug carriers; Dunning prostate cancer; Methotrexate therapy; Methotrexate albumin; Ovarian 342 tumor; Tumor volume doubling time; Walker 256 carcinoma

Indexed keywords

DRUG CARRIER; METHOTREXATE; METHOTREXATE SERUM ALBUMIN; METHOTREXATE-SERUM ALBUMIN; SERUM ALBUMIN;

EID: 0033112951     PISSN: 09594973     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001813-199904000-00009     Document Type: Article
Times cited : (19)

References (23)
  • 2
    • 0030842545 scopus 로고    scopus 로고
    • Plasma protein (albumin) catabolism by the tumor itself-implications for tumor metabolism and the genesis of cachexia
    • Stellte G, Sinn H, Wunder A, et al. Plasma protein (albumin) catabolism by the tumor itself-implications for tumor metabolism and the genesis of cachexia. Crit Rev Oncol Hcmatol 1997; 26: 77-100.
    • (1997) Crit Rev Oncol Hcmatol , vol.26 , pp. 77-100
    • Stellte, G.1    Sinn, H.2    Wunder, A.3
  • 4
    • 0026092328 scopus 로고
    • Identification of tissue sites for increased albumin degradation in sarcomabearing mice
    • Andersson C, Iresjo BM, Lundholm K. Identification of tissue sites for increased albumin degradation in sarcomabearing mice.J Sitrg Res 1991; 50: 156-62.
    • (1991) J Sitrg Res , vol.50 , pp. 156-162
    • Andersson, C.1    Iresjo, B.M.2    Lundholm, K.3
  • 5
    • 12644255693 scopus 로고    scopus 로고
    • Enhanced albumin uptake by rat tumors
    • Wunder A, Stehle G, Sinn H, et al. Enhanced albumin uptake by rat tumors. IntJ Oncol 1997; 11: 497-507.
    • (1997) IntJ Oncol , vol.11 , pp. 497-507
    • Wunder, A.1    Stehle, G.2    Sinn, H.3
  • 6
    • 0029130063 scopus 로고
    • Serum albumin (SA) accumulation by bronchogenic tumours: A tracer technique may help with patient selection for SA-delivered chemotherapy
    • Clonus JH, Sinn H, Manke HG, etal. Serum albumin (SA) accumulation by bronchogenic tumours: a tracer technique may help with patient selection for SA-delivered chemotherapy. EurJ Nucl Med 1995; 22: 989-96.
    • (1995) EurJ Nucl Med , vol.22 , pp. 989-996
    • Clonus, J.H.1    Sinn, H.2    Manke, H.G.3
  • 7
    • 0030766390 scopus 로고    scopus 로고
    • The loading rate determines tumor targeting of methotrexate-albumin conjugates in rats
    • Stehle G, Sinn H, Wunder A, et al. The loading rate determines tumor targeting of methotrexate-albumin conjugates in rats. Anti-Cancer Dmgs 1997; 8: 677-85.
    • (1997) Anti-Cancer Dmgs , vol.8 , pp. 677-685
    • Stehle, G.1    Sinn, H.2    Wunder, A.3
  • 8
    • 0030659779 scopus 로고    scopus 로고
    • Pharmacokinetics of methotrexate-albumin conjugates in tumor bearing rats
    • Stehle G, Wunder A, Sinn H, et al. Pharmacokinetics of methotrexate-albumin conjugates in tumor bearing rats. Anti-Cancer Dmgs 1997; 8: 835-44.
    • (1997) Anti-Cancer Dmgs , vol.8 , pp. 835-844
    • Stehle, G.1    Wunder, A.2    Sinn, H.3
  • 9
    • 0032503593 scopus 로고    scopus 로고
    • Antitumor activity of methotrexate-albumin conjugates in rats bearing a Walker-256 carcinosarcoma
    • Wunder A, Stelile G, Schrenk HH, et al. Antitumor activity of methotrexate-albumin conjugates in rats bearing a Walker-256 carcinosarcoma. IntJ Cancer 1998; 76: 88490.
    • (1998) IntJ Cancer , vol.76 , pp. 88490
    • Wunder, A.1    Stelile, G.2    Schrenk, H.H.3
  • 10
    • 0001256561 scopus 로고
    • Prostate cancer in the rat
    • Dunning WF. Prostate cancer in the rat. NCI Monogr 1963; 12: 351-69.
    • (1963) NCI Monogr , vol.12 , pp. 351-369
    • Dunning, W.F.1
  • 11
    • 0027202227 scopus 로고
    • Measurement of the proliferative activity of three different sublines of the Dunning rat prostate tumor R3327
    • Lolir F, Wenz F, Flentje M, Peschke P, Haiin EW. Measurement of the proliferative activity of three different sublines of the Dunning rat prostate tumor R3327. Strahlcnther Onkol 1993; 169: 438-45.
    • (1993) Strahlcnther Onkol , vol.169 , pp. 438-445
    • Lolir, F.1    Wenz, F.2    Flentje, M.3    Peschke, P.4    Haiin, E.W.5
  • 12
    • 0027275509 scopus 로고
    • The relative biological effectiveness (RBE) of fast neutrons on the Dunning rat prostate carcinoma R3327-HI
    • Wenz F, Lolir F, Peschke P, Wolber G, Hover KH, Hahn EW. [The relative biological effectiveness (RBE) of fast neutrons on the Dunning rat prostate carcinoma R3327-HI]. Strahlcnther Onkol 1993; 169: 412-7.
    • (1993) Strahlcnther Onkol , vol.169 , pp. 412-417
    • Wenz, F.1    Lolir, F.2    Peschke, P.3    Wolber, G.4    Hover, K.H.5    Hahn, E.W.6
  • 13
    • 0017754904 scopus 로고
    • Characterization of the Dunning R3327H prostatic adenocarcinoma: An appropriate animal model for prostatic cancer
    • Smolev JK, Heston WDW, Scott WW, Coffey DS. Characterization of the Dunning R3327H prostatic adenocarcinoma: an appropriate animal model for prostatic cancer. Cancer Treat Rep 1977; 61: 273-87.
    • (1977) Cancer Treat Rep , vol.61 , pp. 273-287
    • Smolev, J.K.1    Wdw, H.2    Scott, W.W.3    Coffey, D.S.4
  • 14
    • 0018076676 scopus 로고
    • Animal models of the hormone-sensitive and -insensitive prostatic adenocarcinomas Dunning R-3327-H, R-3327-HI, and R-3327-AT
    • Isaacs JT, Heston WDW, Weissman RM, Coffey DS. Animal models of the hormone-sensitive and -insensitive prostatic adenocarcinomas Dunning R-3327-H, R-3327-HI, and R-3327-AT. Cancer Res 1978; 38: 4353-9.
    • (1978) Cancer Res , vol.38 , pp. 4353-4359
    • Isaacs, J.T.1    Wdw, H.2    Weissman, R.M.3    Coffey, D.S.4
  • 16
    • 0028997762 scopus 로고
    • Genetic instability assessed by sister chromatid exchange analysis in the Dunning R-3327 rat prostatic adenocarcinoma model and its relationship to metastatic potential
    • Sharief Y, Molller JL Genetic instability assessed by sister chromatid exchange analysis in the Dunning R-3327 rat prostatic adenocarcinoma model and its relationship to metastatic potential. Prostate 1995; 26: 247-52.
    • (1995) Prostate , vol.26 , pp. 247-252
    • Sharief, Y.1    Molller, J.L.2
  • 17
    • 0025135550 scopus 로고
    • Expression and localization of androgen receptor in the R-3327 Dunning rat prostatic adenocarcinoma
    • Quarmby VE, Beckman WCJ, Cooke DB, et al. Expression and localization of androgen receptor in the R-3327 Dunning rat prostatic adenocarcinoma. Cancer Res 1990; 50: 735-9-
    • (1990) Cancer Res , vol.50 , pp. 735-739
    • Quarmby, V.E.1    Wcj, B.2    Cooke, D.B.3
  • 18
    • 0025961693 scopus 로고
    • Flow cytometric measurement of cell cycle kinetics in rat Walker-256 carcinoma following in vivo and in vitro pulse labelling with bromodeoxyuridine
    • Fogt F, Wan J, O'Hara C, Bistrian BR, Blackburn GL, Istfan NW. Flow cytometric measurement of cell cycle kinetics in rat Walker-256 carcinoma following in vivo and in vitro pulse labelling with bromodeoxyuridine. Cytoinetiy 1991; 12: 33-41.
    • (1991) Cytoinetiy , vol.12 , pp. 33-41
    • Fogt, F.1    Wan, J.2    O'Hara, C.3    Bistrian, B.R.4    Blackburn, G.L.5    Istfan, N.W.6
  • 19
    • 0021961581 scopus 로고
    • Blood volume in the m
    • Lee HB, Blaufox MD. Blood volume in the m.JNuclMed 1985; 26: 72-6.
    • (1985) JNuclMed , vol.26 , pp. 72-76
    • Lee, H.B.1    Blaufox, M.D.2
  • 20
    • 0030937267 scopus 로고    scopus 로고
    • Multidmg resistance in androgen-independent growing rat prostate carcinoma cells is mediated by P-glycoprotein
    • Siegsmund MJ, Kreukler C, Steidler A, Nebe T, Kohrmann KU, Alken P. Multidmg resistance in androgen-independent growing rat prostate carcinoma cells is mediated by P-glycoprotein. Urol Res 1997; 25: 35-41.
    • (1997) Urol Res , vol.25 , pp. 35-41
    • Siegsmund, M.J.1    Kreukler, C.2    Steidler, A.3    Nebe, T.4    Kohrmann, K.U.5    Alken, P.6
  • 21
    • 0027414782 scopus 로고
    • The design and application of residualizing labels for the studies of protein catabolism
    • Thorpe SR, Baynes JW, Clironeos ZC. The design and application of residualizing labels for the studies of protein catabolism. FASEBJ 1993; 7: 399-405.
    • (1993) FASEBJ , vol.7 , pp. 399-405
    • Thorpe, S.R.1    Baynes, J.W.2    Clironeos, Z.C.3
  • 22
    • 0008901910 scopus 로고    scopus 로고
    • In vivo activity of a methotrexate-albumin conjugate (MTX-HSA) in human tumor xenografts
    • (abstr).
    • Fiebig HH, Roth T, Härtung G, Sinn H, Stehle G. In vivo activity of a methotrexate-albumin conjugate (MTX-HSA) in human tumor xenografts. Enr J Cancer 1997; 33 (suppl 8): S174 (abstr).
    • (1997) Enr J Cancer , vol.33 , Issue.8 SUPPL.
    • Fiebig, H.H.1    Roth, T.2    Härtung, G.3    Sinn, H.4    Stehle, G.5
  • 23
    • 4243509342 scopus 로고    scopus 로고
    • Phase-1 trial of a methotrexate-albumin conjugate OfTX-HSA in cancer patients
    • (abstr).
    • Härtung G, Stehle G, Sinn H, et al. Phase-1 trial of a methotrexate-albumin conjugate OfTX-HSA) in cancer patients. Eitr J Cancer 1997; 33 (suppl 8) S249-50 (abstr).
    • (1997) Eitr J Cancer , vol.33 , Issue.8 SUPPL.
    • Härtung, G.1    Stehle, G.2    Sinn, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.