The effects of androgen deprivation on the prostate gland: Cell death mediated by vascular regression

Current Opinion in Urology

Volumn 10, Issue 5, 2000, Pages 415-420

  Buttyan, Ralph ^a   Ghafar, Mohamed A ^a   Shabsigh, Ahmad ^a  

^a College of Physicians and Surgeons of Columbia University ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN;

ARTICLE; BLOOD FLOW; BLOOD VESSEL; CASTRATION; CELL DEATH; CELL GROWTH; GRAFT PATENCY; HORMONAL REGULATION; HYPOXIA; ISCHEMIA; NONHUMAN; PARENCHYMA; PRIORITY JOURNAL; PROSTATE; RAT;

ANDROGEN ANTAGONISTS; ANDROGENS; APOPTOSIS; CASTRATION; HUMANS; MALE; PROSTATE; PROSTATIC NEOPLASMS; REGIONAL BLOOD FLOW;

EID: 0033822330     PISSN: 09630643     EISSN: None     Source Type: Journal    
DOI: 10.1097/00042307-200009000-00009     Document Type: Article

References (29)

1. Regulation of apoptosis in the prostate gland by androgenic steroids
2. Cellular events in experimental unilateral ischemic renal atrophy and in regeneration after contralateral nephrectomy
3. Morphological, biochemical and molecular evidence of apoptosis during the reperfusion phase following brief periods of renal ischemia
4. Biochemical and molecular characteristics of the brain with developing cerebral infarction
5. Death by design. Programmed cell death in cardiovascular biology and disease
6. Transient ischemia induces apoptosis in the ventral prostate of the rat
7. Decrement of blood flow precedes the involution of the ventral prostate in the rat after castration
8. Rapid reduction in blood flow to the rat ventral prostate gland after castration. Preliminary evidence that androgens influence prostate size by regulating blood flow to the prostate gland and prostatic endothelial cell survival
9. Early effects of castration on the vascular system of the rat ventral prostate gland
10. Castration induces acute vasoconstriction of blood vessels in the rat prostate concomitant with a reduction of prostatic nitric oxide synthase activity
11. Nitric oxide: A physiologic messenger molecule
12. Androgen receptor localization in different cell types of the adult rat prostate
13. Immunocytochemical analysis of androgen receptors along the ducts of the separate rat prostate lobes after androgen withdrawal and replacement
14. The novel estrogen receptor-beta subtype: Potential role in the cell- and promoter-specific actions of estrogens and anti-estrogens
15. Expression of vascular endothelial growth factor and its receptors in the rat ventral prostate and Dunning R3327 PAP adenocarcinoma before and after castration
16. Regional concentration of basic fibroblast growth factor in normal and benign hyperplastic human prostates
17. Expression of transforming growth factor-β in the rat ventral prostate during castration-induced programmed cell death
18. Adrenomedullin gene is abundantly expressed and directly regulated by androgen in the rat ventral prostate
19. Relaxin in the male
20. Calcium channel antagonists delay regression of androgen-dependent tissues and suppress the gene activity associated with cell death
21. 2+-dependent endonuclease as an early event in castration-induced prostatic cell death
22. Fas antigen/CD-95 upregulation and activation during castration-induced regression of the rat ventral prostate gland
23. Hormonal control of apoptosis: The rat ventral prostate gland as a model system
24. Testosterone stimulates angiogenesis and vascular regrowth in the ventral prostate in castrated rats
25. Treatment of prostatic bleeding: Suppression of angiogenesis by androgen deprivation
26. Effects of finasteride on hematuria associated with benign prostatic hyperplasia: Long term followup
27. Role of finasteride in the treatment of recurrent hematuria secondary to benign prostatic hyperplasia
28. Analysis of the capillary architecture in the precursors of prostate cancer: Recent findings and new concepts
29. Correlation between proliferation, apoptosis and angiogenesis in prostate carcinoma and their relation to androgen ablation