Interleukin-2 and histamine in combination inhibit tumour growth and angiogenesis in malignant glioma

British Journal of Cancer

Volumn 83, Issue 6, 2000, Pages 826-832

  Johansson, M ^a   Henriksson, R ^a   Bergenheim, A T ^a   Koskinen, L O D ^a  

^a UMEÅ UNIVERSITY   (Sweden)

Author keywords

Angiogenesis; Glioma; Histamine; IL 2; Microvascular density; Rat

Indexed keywords

HISTAMINE; INTERLEUKIN 2; MESSENGER RNA; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BRAIN TUMOR; CANCER INHIBITION; CELL ACTIVITY; CONTROLLED STUDY; GLIOBLASTOMA; MICROVASCULATURE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; TUMOR BLOOD FLOW;

EID: 0033817067     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1054/bjoc.2000.1354     Document Type: Article

References (38)

1. The effect of interleukin-2 on the blood-brain barrier in the 9L gliosarcoma rat model
2. Histaminergic regulation of natural killer cell-mediated clearance of tumour cells in mice
3. Intratumoral LAK cell and interleukin-2 therapy of human gliomas
4. Intratumoral LAK cell and interleukin-2 therapy of human gliomas
5. Cytotoxic effect and uptake of estramustine in a rat glioma model
6. Vascular permeability induced by protein product of malignant brain tumors: Inhibition by dexamethasone
7. Decrease in tumour growth by injections of histamine or serotonin in fibrosarcoma-bearing mice: Influence of H1 and H2 histamine receptors
8. Selective modulation of human natural killer cells in vivo after prolonged infusion of low dose recombinant interleulkin 2
9. Interleukin-2 (IL-2) in the treatment of malignant brain tumors (glioblastomas)
10. The heterogeneity of mononuclear phagocytes in lymphoid organs: Distinct macrophage subpopulations in the rat recognized by monoclonal antibodies ED1, ED2 and ED3
11. Priming in the brain, an immunologically privileged organ, elicits anti-tumor immunity
12. A 9L gliosarcoma transplantation model for studying adoptive immunotherapy into the brains of conscious rats
13. Glioblastoma cells release interleukin 1 and factors inhibiting interleukin 2-mediated effects
14. Intracerebral versus subcutaneous immunization with allogeneic fibroblasts genetically engineered to secrete interleukin-2 in the treatment of central nervous system glioma and melanoma
15. Improved long term survival after intracavitary interleukin-2 and lymphokine-activated killer cells for adults with recurrent malignant glioma
16. Mechanism of dexamethasone suppression of brain tumor-associated vascular permeability in rats. Involvement of the glucocorticoid receptor and vascular permeability factor
17. Synergistic activation of human natural killer cell cytotoxicity by histamine and interleukin-2
18. Role of histamine in natural killer cell-mediated resistance against tumor cells
19. Histaminergic regulation of NK cells. Role of monocyte-derived reactive oxygen metabolites
20. Histamine in immunotherapy of advanced melanoma: A pilot study
21. Interleukin-2-induced growth inhibition of prostatic adenocarcinoma (Dunning R3327) in rats
22. Survival in renal cell carcinoma - A randomized evaluation of tamoxifen vs interleukin 2, alpha-interferon (leucocyte) and tamoxifen
23. Generation of cytotoxic immune responses against a rat glioma by in vivo priming and secondary in vitro stimulation with tumor cells
24. Tumor blood flow and the cytotoxic effects of estramustine and its constituents in a rat glioma model
25. The response of Dunning R3327 prostatic adenocarcinoma to IL-2, histamine and radiation
26. Macrophage role in the anti-prostate cancer response to one class of antiangiogenic agents
27. Treatment of recurrent glioma with intracavitary alloreactive cytotoxic T lymphocytes and interleukin-2
28. Long-term follow-up of patients with recurrent malignant gliomas treated with adjuvant adoptive immunotherapy
29. VEGF and tPA co-expressed in malignant glioma
30. Immunotherapy of metastatic renal cell carcinoma
31. During angiogenesis, vascular endothelial growth factor and basic fibroblast growth factor regulate natural killer cell adhesion to tumor endothelium
32. Effect of histamine on the blood-tumor barrier in transplanted rat brain tumors
33. Treatment of murine primary brain tumors with systemic interleukin-2 and tumor-infiltrating lymphocytes
34. In vivo and in vitro effect of adoptive immunotherapy of experimental murine brain tumors using lymphokine-activated killer cells
35. Adoptive immunotherapy of a rat glioma using lymphokine-activated killer ceils and interleukin 2
36. Influence of interleukin II on xenotransplanted grade 3 to 4 glioma in nude mice
37. Tumor angiogenesis: Review of current applications in tumour prognostication
38. A new method to detect apoptosis in paraffin sections: In situ end-labelling of fragmented DNA