The response of Dunning R3327 prostatic adenocarcinoma to IL-2, histamine and radiation

British Journal of Cancer

Volumn 77, Issue 8, 1998, Pages 1213-1219

  Johansson, S ^a,d   Landstrom M ^a,b   Hellstrand, K ^c   Henriksson, R ^a  

^a UMEÅ UNIVERSITY   (Sweden)

^b UPPSALA UNIVERSITY   (Sweden)

^c UNIVERSITY OF GOTHENBURG   (Sweden)

^d UMEÅ UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Dunning R3327 prostatic carcinoma; Histamine; Interleukin 2; Radiation

Indexed keywords

HISTAMINE; RECOMBINANT INTERLEUKIN 2;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; MALE; NONHUMAN; OSMOTIC MINIPUMP; PRIORITY JOURNAL; PROSTATE ADENOCARCINOMA; RADIATION; RAT; SUBCUTANEOUS DRUG ADMINISTRATION; TUMOR GROWTH; TUMOR VOLUME;

EID: 0031910649     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/bjc.1998.205     Document Type: Article

References (22)

1. Asea A, Hermodsson S and Hellstrand K (1996) Histaminergic regulation of natural killer cell-mediated clearance of tumour cells in mice. Scand J Immunol 43: 9-15
2. Atzpodien J, Lopez Hanninen E, Kirchner H, Bodenstein H, Pfreundschuh M, Rebmann U, Metzner B, Illiger HJ, Jakse G and Niesel T (1995). Multiinstitutional home-therapy trial of recombinant human interleukin-2 and interferon alfa-2 in progressive metastatic renal cell carcinoma. J Clin Oncol 13: 497-501.
3. Brune M and Hellstrand K (1996) Remission maintenance therapy with histamine and interleukin-2 in acute myelogenous leukaemia. Br J Haematol 92: 620-626
4. Burtin C, Ponvert C, Fray A, Scheinmann P, Lespinats G, Loridon B, Canu P and Paupe J (1985) Inverse correlation between tumor incidence and tissue histamine levels in W/WV, WV/+. and +/+ mice. J Natl Cancer Inst 74: 671-674
5. Caligiuri MA, Murray C, Robertson MJ, Wang E, Cochran K, Cameron C, Schow P, Ross ME, Klumpp TR and Soiffer RJ (1993). Selective modulation of human natural killer cells in vivo after prolonged infusion of low dose recombinant interleukin 2. J Clin Invest 91: 123-132
6. Denekamp J (1990) Vascular attack as a therapeutic strategy for cancer. Cancer Metastas Rev 9: 267-282
7. Hellstrand K and Hermodsson S (1990) Synergistic activation of human natural killer cell cytotoxicity by histamine and interleukin-2. Int Arch Allergy Appl Immunol 92: 379-389
8. Hellstrand K, Naredi P, Lindner P, Lundholm K, Rudenstam CM, Hermodsson S, Asztely M and Hafstrom L (1994a) Histamine in immunotherapy of advanced melanoma: a pilot study. Cancer Immunol Immunother 39: 416-419
9. Hellstrand K, Asea A, Dahlgren C & Hermodsson S (1994b). Histaminergic regulation of NK cells. Role of monocyte-derived reactive oxygen metabolites. J Immunol 153: 4940-4947
10. Henriksson R, Widmark A, Bergh A and Damber JE (1992) Interleukin-2-induced growth inhibition of prostatic adenocarcinoma (Dunning R3327) in rats. Urol Res 20: 189-191
11. Isaacs JT (1987) Development and characteristics of the available animal model systems for the study of prostatic cancer. Prog Clin Biol Res 239: 513-576.
12. Lahat N, Alexander B, Levin DR and Moskovitz B (1989) The relationship between clinical stage, natural killer activity and related immunological parameters in adenocarcinoma of the prostate. Cancer Immunol Immunother 28: 208-212
13. Landstrom M and Funa K (1997) Ápoptosis in rat prostatic adenocarcinoma is associated with a rapid infiltration of cytotoxic T-cells and activated macrophages. Int J Cancer 71: 451-455
14. Mador D, Ritchie B, Meeker B, Moore R, Elliott FG, McPhee MS, Chapman JD and Lakey WH (1982) Response of the Dunning R3327H prostatic adenocarcinoma to radiation and various chemotherapeutic drugs. Cancer Treat Rep 66: 1837-1843
15. Meikle AW, Smith JA and Stringham JD (1987) Production, clearance, and metabolism of testosterone in men with prostatic cancer. Prostate 10: 25-31
16. Meyer JS and He W (1993) Cell proliferation measurements by bromodeoxyuridine or thymidine incorporation: clinical correlates. Semin Radiat Oncol 3: 126-134
17. Moody DB, Robinson JC, Ewing CM, Lazenby AJ and Isaacs WB (1994) Interleukin-2 transfected prostate cancer cells generate a local antitumor effect in vivo. Prostate 24: 244-251
18. Peri G, Chiaffarino F, Bernasconi S, Padura IM and Mantovani A (1990) Cytotoxicity of activated monocytes on endothelial cells. J Immunol 144: 1444-1448
19. Reizenstein P, Ogier C, Blomgren H, Petrini B and Wasserman J (1985) Cells responsible for tumor surveillance in man: effects of radiotherapy, chemotherapy, and biologic response modifiers. Adv Immun Cancer Ther 1: 1-28
20. Smolev JK, Coffey DS and Scott WW (1977) Experimental models for the study of prostatic adenocarcinoma. J Urol 118: 216-220
21. Thorndyke C, Meeker BE, Thomas G, Lakey WH, McPhee MS and Chapman JD (1985) The radiation sensitivities of R3327-H and R3327-AT rat prostate adenocarcinomas. J Urol 134: 191-198
22. Van Loveren H, Den Otter W, Meade R, Terheggen PM and Askenase PW (1985) A role for mast cells and the vasoactive amine serotonin in T cell-dependent immunity to tumors. J Immunol 134: 1292-1299