A QSAR study investigating the effect of L-alanine ester variation on the anti-HIV activity of some phosphoramidate derivatives of d4T

Bioorganic and Medicinal Chemistry Letters

Volumn 10, Issue 18, 2000, Pages 2075-2078

  Knaggs, Michael H ^a   McGuigan, Christopher ^a   Harris, Sarah A ^a   Heshmati, Parissa ^a   Cahard, Dominique ^a   Gilbert, Ian H ^a   Balzarini, Jan ^b  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; PHOSPHORAMIDIC ACID DERIVATIVE; STAVUDINE; STAVUDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; ARTIFICIAL NEURAL NETWORK; CYTOTOXICITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; STRUCTURE ACTIVITY RELATION; T LYMPHOCYTE;

ALANINE; AMIDES; ANTI-HIV AGENTS; CELL DEATH; HIV-1; HIV-2; MODELS, CHEMICAL; MODELS, MOLECULAR; PHOSPHORIC ACIDS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; STAVUDINE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0033813236     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(00)00397-8     Document Type: Article

References (12)