Evidence for apoptosis of the majority of T cells activated in vitro with Actinobacillus actinomycetemcomitans

Oral Microbiology and Immunology

Volumn 15, Issue 5, 2000, Pages 290-298

  Nalbant, A ^a   Zadeh, H H ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Actinobacillus actinomycetemcomitans; Annexin V; Apoptosis; Periodontitis; Propidium iodide; T cells; Virulence factors

Indexed keywords

EID: 0033811382     PISSN: 09020055     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-302x.2000.150504.x     Document Type: Article

References (60)

1. Binding of vascular anticoagulant alpha (VAC alpha) to planar phospholipid bilayers
2. Polymerase chain reaction detection of 8 putative periodontal pathogens in subgingival plaque of gingivitis and advanced periodontitis lesions
3. A role for CD95 ligand in preventing graft rejection
4. Cell death mediators in autoimmune diabetes-no shortage of suspects
5. Changes in membrane phospholipid distribution during platelet activation
6. Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g
7. Exposure of phosphatidylserine in the outer leaflet of human red blood cells. Relationship to cell density, cell age, and clearance by mononuclear cells
8. The annexins and exocytosis
9. Particle digestibility is required for induction of the phosphatidylserine recognition mechanism used by murine macrophages to phagocytose apoptotic cells
10. Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages
11. Apoptosis in cancer therapy: Crossing the threshold
12. Potential involvement of Fas and its ligand in the pathogenesis of Hashimoto's thyroiditis
13. Programmed cell death in AIDS-related HIV and SIV infections
14. + T-lymphocytes in asymptomatic HIV infected patients induce the program action of lymphocyte death by apoptosis
15. + T cells from human immunodeficiency virus-infected asymptomatic individuals
16. Melanoma cell expression of Fas(Apo-1/ CD95) ligand: Implications for tumor immune escape
17. Susceptibility of peripheral blood mononuclear cells to apoptosis is correlated to plasma HIV load
18. Evidence for apoptosis of murine macrophages by Actinobacillus actinomycetemcomitans infection
19. Characterization of the lipopolysaccharide from Actinobacillus actinomycetemcomitans Y4 and N27
20. cis Elements and trans factors are both important in strain-specific regulation of the leukotoxin gene in Actinobacillus actinomycetemcomitans
21. Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis
22. Actinobacillus actinomycetemcomitans leukotoxin induces apoptosis in HL-60 cells
23. Immunosuppressive effect induced by Actinobacillus actinomycetemcomitans: Effect on immunoglobulin production and lymphokine synthesis
24. Analysis of the Actinobacillus actinomycetemcomitans leukotoxin gene. Delineation of unique features and comparison to homologous toxins
25. Rapid flow cytometric method for measuring lymphocyte subset activation
26. Lethal effects of Actinobacillus actinomycetemcomitans leukotoxin on human T lymphocytes
27. Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: Inhibition by overexpression of Bcl-2 and Ab1
28. Profound deletion of matue T cells in vivo by chronic exposure to exogenous superantigen
29. Anti-proliferative and cytotoxic activity of surface-associated material from periodontopathogenic bacteria
30. Extracts of Actinobacillus actinomycetemcomitans induce apoptotic cell death in human osteoblastic MG63 cells
31. Role of CD14 molecules in internalization of Actinobacillus actinomycetemcomitans by macrophages and subsequent induction of apoptosis
32. Actinobacillus actinomycetemcomitans toxin induces both cell cycle arrest in the G2/M phase and apoptosis
33. Amyloid beta peptide of Alzheimer's disease downregulates Bcl-2 and upregulates bax expression in human neurons
34. A model for p53-induced apoptosis
35. Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype
36. Collagenolytic activity associated with Bacteroides species and Actinobacillus actinomycetemcomitans
37. Activation-induced death of mature T cells in the regulation of immune responses
38. Immune suppression induced by Actinobacillus actinomycetemcomitans. I. Effects on human peripheral blood lymphocyte responses to mitogens and antigens
39. Immune suppression induced by Actinobacillus actinomycetemcomitans: Effects on immunoglobulin production by human B cells
40. Selective medium for isolation of Actinobacillus actinomycetemcomitans
41. Black-pigmented Bacteroides species, Capnocytophaga species, and Actinobacillus actinomycetemcomitans in human periodontal disease: Virulence factors in colonization, survival, and tissue destruction
42. The regulation of leukotoxin production in Actinobacillus actinomycetemcomitans strain JP2
43. Factors influencing the growth and viability of Actinobacillus actinomycetemcomitans
44. Lymphocyte apoptosis induced by CD95 (APO-1/Fas) ligand-expressing tumor cells-a mechanism of immune evasion?
45. The role of the bcl-2/ced-9 gene family in cancer and general implications of defects in cell death control for tumourigenesis and resistance to chemotherapy
46. Yersinia enterocolitica produces superantigenic activity
47. Biochemical and morphological characterization of the killing of human monocytes by a leukotoxin derived from Actinobacillus actinomycetemcomitans
48. Apoptosis in the pathogenesis and treatment of disease
49. Extraction and partial characterization of a leukotoxin from a plaque-derived gramnegative microorganism
50. Extraction and isolation of a leukotoxin from Actinobacillus actinomycetemcomitans with polymyxin B
51. Inhibition of neutrophil chemotaxis by soluble bacterial products
52. Mechanisms of phosphatidylserine exposure, a phagocyte recognition signal, on apoptotic T lymphocytes
53. Requirement of the familial Alzheimer's disease gene PS2 for apoptosis. Opposing effect of ALG-3
54. Clonal deletion as direct consequence of an in vivo T cell response to bacterial superantigen
55. Participation of presenilin 2 in apoptosis: Enhanced basal activity conferred by an Alzheimer mutation
56. Largescale early T-cell response to Actinobacillus actinomycetemcomitants suggests antigen non-specific activation
57. Evidence for involvement of superantigens in human periodontal diseases: Skewed expression of T cell receptor variable regions by gingival T cells
58. The role of the T cell-mediated immune response to Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis in periodontitis
59. Platelet phospholipid asymmetry and its significance in hemostasis
60. Pathophysiologic implications of membrane phospholipid asymmetry in blood cells