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Volumn 17, Issue 2 SUPPL. 1, 1997, Pages

The clinical relevance of preclinical data: Mirtazapine, a model compound

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; MIRTAZAPINE;

EID: 0030906584     PISSN: 02710749     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper
Times cited : (40)

References (16)
  • 1
    • 0029953756 scopus 로고    scopus 로고
    • Mirtazapine: A review of its pharmacology and therapeutic potential in the management of major depression
    • Davis R, Wilde MI. Mirtazapine: a review of its pharmacology and therapeutic potential in the management of major depression. CNS Drugs 1996;5:398-402.
    • (1996) CNS Drugs , vol.5 , pp. 398-402
    • Davis, R.1    Wilde, M.I.2
  • 2
    • 0029056606 scopus 로고
    • 1A-mediated serotonergic neurotransmission
    • 1A-mediated serotonergic neurotransmission. CNS Drugs 1995;4[suppl 1]:29-38.
    • (1995) CNS Drugs , vol.4 , Issue.1 SUPPL. , pp. 29-38
    • De Boer, Th.1    Ruigt, G.2
  • 3
    • 0027946920 scopus 로고
    • Design of drugs through a consideration of drug metabolism and pharmacokinetics
    • Smith DA. Design of drugs through a consideration of drug metabolism and pharmacokinetics. Eur J Drug Metab Pharmacokinet 1994;3:193-9.
    • (1994) Eur J Drug Metab Pharmacokinet , vol.3 , pp. 193-199
    • Smith, D.A.1
  • 4
    • 0023837235 scopus 로고
    • 2-adrenoceptor blockade in the central nervous system and the effects of the enantiomers of mianserin and its aza-analog Org 3770
    • 2-adrenoceptor blockade in the central nervous system and the effects of the enantiomers of mianserin and its aza-analog Org 3770. Arch Int Pharmacodyn Ther 1988;291:185-201.
    • (1988) Arch int Pharmacodyn Ther , vol.291 , pp. 185-201
    • Gower, A.J.1    Broekkamp, C.L.E.2    Rijk, H.W.3    Van Delft, A.M.4
  • 5
    • 0028818229 scopus 로고
    • Species, similarities and differences in pharmacokinetics
    • Lin JH. Species, similarities and differences in pharmacokinetics. Drug Metab Dispos Biol Fate Chem 1995;23:1008-21.
    • (1995) Drug Metab Dispos Biol Fate Chem , vol.23 , pp. 1008-1021
    • Lin, J.H.1
  • 6
    • 0028303820 scopus 로고
    • Plasma protein binding displacement interactions
    • Rolan PE. Plasma protein binding displacement interactions. Br J Clin Pharmacol 1994;37:125-8.
    • (1994) Br J Clin Pharmacol , vol.37 , pp. 125-128
    • Rolan, P.E.1
  • 7
    • 0028942901 scopus 로고
    • What is the true clinical significance of plasma protein binding displacement interactions
    • Samson LN, Evans AM. What is the true clinical significance of plasma protein binding displacement interactions. Drug Saf 1995; 12:227-33.
    • (1995) Drug Saf , vol.12 , pp. 227-233
    • Samson, L.N.1    Evans, A.M.2
  • 8
    • 0029028790 scopus 로고
    • Bioavailability of mirtazapine from Remeron tablets after single and multiple oral dosing
    • Voortman G, Paanakker JE. Bioavailability of mirtazapine from Remeron tablets after single and multiple oral dosing. Hum Psychopharmacol 1995;10[suppl 2]:S83-96.
    • (1995) Hum Psychopharmacol , vol.10 , Issue.2 SUPPL.
    • Voortman, G.1    Paanakker, J.E.2
  • 9
    • 0028347408 scopus 로고
    • Metabolism of three pharmacologically active drugs in isolated human and rat hepatocytes: Analysis of interspecies variability and comparison with metabolism in vivo
    • Sandker GW, Vos RME, Delbressine LPC, Slooff MJH, Meijer DKF, Groothuis GMM. Metabolism of three pharmacologically active drugs in isolated human and rat hepatocytes: analysis of interspecies variability and comparison with metabolism in vivo. Xenobiotica 1994;24:143-55.
    • (1994) Xenobiotica , vol.24 , pp. 143-155
    • Sandker, G.W.1    Vos, R.M.E.2    Delbressine, L.P.C.3    Slooff, M.J.H.4    Meijer, D.K.F.5    Groothuis, G.M.M.6
  • 10
    • 0028237729 scopus 로고
    • Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: Studies with liver microsomes of 30 Japanese and 30 Caucasians
    • Shimada T, Yamazaki H, Mimura M, Inui Y, Guengerich FP. Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians. J Pharmacol Exp Ther 1994;270:414-23.
    • (1994) J Pharmacol Exp Ther , vol.270 , pp. 414-423
    • Shimada, T.1    Yamazaki, H.2    Mimura, M.3    Inui, Y.4    Guengerich, F.P.5
  • 12
    • 0030016458 scopus 로고    scopus 로고
    • Cytochrome P450 enzymes: Interpretation of their interactions with selective serotonin uptake inhibitors. Part I
    • Harvey AT, Preskom SH. Cytochrome P450 enzymes: interpretation of their interactions with selective serotonin uptake inhibitors. Part I. J Clin Psychopharmacol 1996;16: 273-85.
    • (1996) J Clin Psychopharmacol , vol.16 , pp. 273-285
    • Harvey, A.T.1    Preskom, S.H.2
  • 13
    • 0030036673 scopus 로고    scopus 로고
    • Relationship of in vitro data on drug metabolism to in vivo pharmacokinetics and drug interactions: Implications for diazepam disposition in humans
    • Schmider J, Greenblatt DJ, von Moltke LL, Shader RI. Relationship of in vitro data on drug metabolism to in vivo pharmacokinetics and drug interactions: implications for diazepam disposition in humans. J Clin Psychopharmacol 1996;16:267-72.
    • (1996) J Clin Psychopharmacol , vol.16 , pp. 267-272
    • Schmider, J.1    Greenblatt, D.J.2    Von Moltke, L.L.3    Shader, R.I.4
  • 14
    • 0029074770 scopus 로고
    • Pharmacokinetic doseproportionality study at steady state of mirtazapine from Remeron® tables
    • Timmer CJ, Lohmann AAM, Mink CPA. Pharmacokinetic doseproportionality study at steady state of mirtazapine from Remeron® tables. Hum Psychopharmacol 1995;10[suppl 2]:97-106.
    • (1995) Hum Psychopharmacol , vol.10 , Issue.2 SUPPL. , pp. 97-106
    • Timmer, C.J.1    Lohmann, A.A.M.2    Mink, C.P.A.3
  • 15
    • 0001131495 scopus 로고
    • Behavior and analysis of rapid equilibrium and steady-state enzyme systems
    • New York: John Wiley
    • Segel IH. Behavior and analysis of rapid equilibrium and steady-state enzyme systems. In: Enzyme kinetics. New York: John Wiley, 1975:100-226.
    • (1975) Enzyme Kinetics , pp. 100-226
    • Segel, I.H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.