Ammonia, respiration, and longevity in nematodes: Insights on metabolic regulation of life span from temporal rescaling

Journal of the American Aging Association

Volumn 23, Issue 2, 2000, Pages 75-84

  Thaden, John J ^a,b   Shmookler Reis, Robert J ^a,b,c  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^c CENTRAL ARKANSAS VETERANS HEALTHCARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; AMMONIA; INSULIN; LUCIGENIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

ARTICLE; BREATHING; CAENORHABDITIS ELEGANS; LIFESPAN; LONGEVITY; METABOLIC REGULATION; METABOLISM; NEMATODE; NONHUMAN; OXYGEN CONSUMPTION; SIGNAL TRANSDUCTION; STRAIN DIFFERENCE; UREA CYCLE;

EID: 0033803957     PISSN: 01619152     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11357-000-0008-7     Document Type: Article

References (57)

1. Daf-12 regulates developmental age and the dauer alternative in Caenorhabditis elegans
2. Quantitative measures of aging in the nematode C. elegans. I. Population and longitudinal studies of two behavioral parameters
3. Apparent uncoupling of energy production and consumption in long-lived Clk mutants of Caenorhabditis elegans
4. Ammonia stimulates glutamine uptake to the cerebral non-synaptic mitochondria of the rat
5. Structural and functional conservation of the Caenorhabditis elegans timing gene clk-1
6. Nematode ageing: Putting metabolic theories to the test
7. Two pleiotropic classes of daf-2 mutation affect larval arrest, adult behavior, reproduction and longevity in Caenorhabditis elegans
8. Effects of intermittent feeding upon body weight and lifespan in inbred mice: Interaction of genotype and age
9. Daf-2, daf-16 and daf-23: Genetically interacting genes controlling dauer formation in Caenorhabditis elegans
10. Temporal patterns of gene expression in the antenna of the adult Drosophila melanogaster
11. Molecular genetics of life span in C. elegans: How much does it teach us?
12. Life span of the wild and mutant nematode Caenorhabditis elegans
13. Environmental factors and gene activities that influence life span
14. AC. elegans mutant that lives twice as long as wild type
15. Embryogenesis and the glyoxylate cycle
16. Caenorhabditis elegans: Decay of isocitrate lyase during larval development
17. Daf-2, an insulin receptor-like gene that regulates iongevity and diapause in Caenorhabditis elegans
18. Effects of acute hyperammonemia in vivo on oxidative metabolism in nonsynaptic rat brain mitochondria
19. +-ATPase
20. Determination of life-span in Caenorhabditis elegans by four Clock genes
21. The genetics of caloric restriction in Caenorhabditis elegans
22. Genes that regulate both development and longevity in Caenor-habditis elegans
23. Daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans
24. The rate of living theory revisited
25. Thermotolerance and extended life-span conferred by single-gene mutations and induced by thermal stress
26. Temperature and the rate of ageing in poikilotherms
27. Effects of temperature on the life span, vitality and fine structure of Drosophila melanogaster
28. A phosphoinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans
29. A genetic pathway conferring life extension and resistance to UV stress in Caenorhabditis elegans
30. Imbalance of oxygen activation and energy metabolism as a consequence or mediator of aging
31. Intermediary metabolism in the dauer larva of the nematode C. elegans. I. Glycolysis, gluconeogenesis, oxidative phosphorylation and the tricarboxylic acid cycle
32. Intermediary metabolism in the dauer larva of the nematode C. elegans. II. The glyoxylate cycle and fatty acid oxidation
33. The fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans
34. The C. elegans PTEN homolog, DAF-18, acts in the insulin receptor-like metabolic signaling pathway
35. A PDK1 homolog is necessary and sufficient to transduce AGE- 1 PI3 kinase signals that regulate diapause in Caenorhabditis elegans
36. Enzyme induction in recovering dauer larvae of the nematode Caenorhabditis elegans in response to increasing concentrations of food source in the recovery medium
37. Timing of expression of a a gene in the adult Drosophila is regulated by mechanisms independent of temperature and metabolic rate
38. Nematode biochemistry - III. Excretion products
39. Subcellular localization of glyoxylate cycle enzymes in Ascaris suum larvae
40. Genetics of aging: Current animal models
41. Enzymes of the tricarboxylic acid cycle in Ancylostoma ceylanicum and Nippostrongylus brasiliensis
42. Current issues concerning the role of oxidative stress in aging: A perspective
43. Age-specific modulation of light production potential, and alkaline phosphatase and protein tyrosine kinase activities in various age mutants of Caenorhabditis elegans
44. The gerontogenes age-1 and daf- 2 determine metabolic rate potential in aging Caenorhabditis elegans
45. Rate of aerobic metabolism and superoxide production rate potential in the nematode Caenorhabditis elegans
46. A structured, minimal parameter model of the central nitrogen metabolism in Saccharomyces cerevisiae: The prediction of the behavior of mutants
47. Genetic analysis of chemosensory control of dauer formation in Caenorhabditis elegans
48. Developmental regulation of energy metabolism in Caenorhabditis elegans
49. The retardation of aging by caloric restriction: Studies in rodents and primates
50. Inhibition of glutamine synthetase reduces ammonia-induced astrocyte swelling in rat
51. Mutations in the clk-1 gene of Caenorhabditis elegans affect developmental and behavioral timing
52. Elimination of nitrogenous compounds by Panagrellus redivivus, Goodey, 1945 (Nematoda: Cephalobidae)
53. Nitrogen excretion: Three end products, many physiological roles