Evidence for coassembly of mutant GABA(C) ρ1 with GABA(A) γ2S, glycine α1 and glycine α2 receptor subunits in vitro

European Journal of Neuroscience

Volumn 12, Issue 9, 2000, Pages 3137-3145

  Pan, Zhuo Hua ^a,b   Zhang, Dongxian ^a,c   Zhang, Xishan ^a   Lipton, Stuart A ^a,c  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c BURNHAM INSTITUTE   (United States)

Author keywords

Electrophysiological recording; Inhibitory neurotransmitter; Retina; Xenopus laevis oocytes

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID C RECEPTOR; GLYCINE; GLYCINE RECEPTOR; PICROTOXIN; RECEPTOR SUBUNIT;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; DOSE RESPONSE; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN EXPRESSION; RAT; VOLTAGE CLAMP; XENOPUS LAEVIS;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHYSIOLOGY; GABA ANTAGONISTS; GAMMA-AMINOBUTYRIC ACID; GENE EXPRESSION; MUTAGENESIS; NEURAL INHIBITION; OOCYTES; PICROTOXIN; PROTEIN STRUCTURE, TERTIARY; RATS; RECEPTORS, GABA; RECEPTORS, GABA-A; RECEPTORS, GABA-B; RECEPTORS, GLYCINE; RETINA; XENOPUS LAEVIS;

EID: 0033802654     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1460-9568.2000.00198.x     Document Type: Article

References (43)

1. Functional properties of strychnine-sensitive glycine receptors expressed in Xenopus oocytes injected with a single mRNA
2. Role of GABA(A) and GABA(C) receptors in the biphasic GABA responses in neurons of the rat major pelvic ganglia
3. Localization of the ρ1- and ρ2-subunit messenger RNAs in chick retina by in situ hybridization predicts the existence of γ-aminobutyric acid type C receptor subtypes
4. GABA(A) receptor needs two homologous domains of the β-subunit for activation by GABA but not by pentobarbital
5. Excitatory and inhibitory action of GABA on synaptic transmission in slices of guinea pig superior colliculus
6. Glycine receptors: Heterogeneous and widespread in mammalian brain
7. 2+
8. GABA(C) receptor
9. Identification of a putative γ-aminobutyric acid (GABA) receptor subunit rho2 cDNA and colocalization of the genes encoding rho2 (GABRR2) and rho1 (GABRR1) to human chromosome 6q14-q214 and mouse chromosome 4
10. Cloning of the γ-aminobutyric acid (GABA) ρ1 cDNA: A GABA receptor subunit highly expressed in the retina
11. Bicuculline insensitive GABA receptors: Studies on the binding of (-) -baclofen to rat cerebellar membranes
12. Expression of GABA receptor ρ1 and ρ2 subunit in the retina and brain of the rat
13. Pharmacology of GABA receptor channels in rat retinal bipolar cells
14. The strychnine-binding subunit of the glycine receptor shows homology with nicotinic acetycholine receptors
15. Cloning and expression of the 58 kd β subunit of the inhibitory glycine receptor
16. The N-terminal domain of human GABA receptor rho1 subunits contains signals for homooligomeric and heterooligomeric interaction
17. Sequences in the amino termini of GABA ρ and GABA(A) subunits specify their selective interaction in vitro
18. Synaptic clustering of GABA(C) receptor ρ-subunits in the rat retina
19. GABA ρ2 receptor pharmacological profile: GABA recognition site similarities to ρ1
20. Modulation by zinc ions of native rat and recombinant human inhibitory glycine receptors
21. GABA(A) receptor channels
22. An unusual effect of γ-aminobutyric acid on synaptic transmission of frog tectal neurones in vitro
23. Cloning of a putative γ-aminobutyric acid GABA receptor subunit ρ3 cDNA
24. Localization of γ-aminobutyric acid (GABA) receptor ρ3 subunit in rat retina
25. Evolutionary history of the ligand-gated ion-channel superfamily of receptors
26. GABA ρ subunits mutated in the channel domain display spontaneous, GABA-suppressible currents and co-assemble with GABA(A) and glycine receptor subunits
27. Evidence for co-assembly of GABA ρ1 with GABA(A) and glycine subunits in vitro
28. Agonist-induced closure of constitutively open GABA channels with mutated M2 domains
29. Expression of mammalian γ-aminobutyric acid receptors with distinct pharmacology in Xenopus oocytes
30. Importance of a novel GABA(A) receptor subunit for benzodiazepine pharmacology
31. Novel GABA responses from rod-driven retinal horizontal cells
32. Response kinetics and pharmacological properties of heteromeric receptors formed by coassembly of GABA ρ- and γ2-subunits
33. Sequence and functional expression of the GABA A receptor shows a ligand-gated receptor super-family
34. γ-aminobutyric acid A or C receptor? γ-aminobutyric acid ρ1 receptor RNA induces bicuculline-, barbiturate-, and benzodiazepine-insensitive γ-aminobutyric acid responses in Xenopus oocytes
35. Functional expression of GABA ρ3 receptors in Xenopus oocyte
36. GABA receptor mechanisms in the central nervous system
37. GABA(A) receptors are differentially sensitive to zinc: Dependence on subunit composition
38. Functional domains of GABA(A) receptors
39. Transient expression of a novel type of GABA response in rat CA3 hippocampal neurones during development
40. Distribution of GABA receptor ρ subunit transcripts in the rat brain
41. Molecular and functional diversity of the expanding GABA-A receptor gene family
42. Correlation between a bicuculline-resistant response to GABA and GABA(A) receptor ρ1 subunit expression in single rat retinal bipolar cells
43. Cloning of a γ-aminobutyric acid type C receptor subunit in rat retina with a methionine residue critical for picrotoxinin channel block