Agonist-induced closure of constitutively open γ-aminobutyric acid channels with mutated M2 domains

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 12, 1997, Pages 6490-6495

  Pan, Zhuo Hua ^a   Zhang, Dongxian ^a   Zhang, Xishan ^a   Lipton, Stuart A ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

GABA(C) receptors; Site directed mutagenesis; Xenopus oocytes

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID RECEPTOR; ION CHANNEL;

AGONIST; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CHANNEL GATING; NONHUMAN; OOCYTE; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; XENOPUS LAEVIS;

AMINO ACID SEQUENCE; ANIMALS; CLONING, MOLECULAR; FEMALE; GABA AGONISTS; GABA ANTAGONISTS; GAMMA-AMINOBUTYRIC ACID; ION CHANNEL GATING; ION CHANNELS; MACROMOLECULAR SUBSTANCES; MEMBRANE POTENTIALS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; OOCYTES; ORGANOPHOSPHORUS COMPOUNDS; POINT MUTATION; RATS; RECEPTORS, GABA; RECEPTORS, GLYCINE; RECEPTORS, NICOTINIC; RECOMBINANT PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; VIRULENCE FACTORS, BORDETELLA; XENOPUS LAEVIS;

ANIMALIA; XENOPUS LAEVIS;

EID: 0031008480     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.12.6490     Document Type: Article

References (38)

1. Noda, M., Takahashi, H., Tanabe, T., Toyosato, M., Kikyotani, S., Furutani, Y., Hirose, T., Takashima, H., Inayama, S., Miyata, T. & Numa, S. (1983) Nature (London) 302, 528-532.
2. Grenningloh, G., Rienitz, A., Schmitt, B., Methfessel, C., Zensen, M., Beyreuther, K., Gundelfinger, E. D. & Betz, H. (1987) Nature (London) 328, 215-220.
3. Maricq, A. V., Peterson, A. S., Brake, A. J., Myers, R. M. & Julius, D. (1991) Science 254, 432-436.
4. Schofield, P. R., Darlison, M. G., Fujita, N., Burt, D. R., Stephenson, F. A., Rodriguez, H., Rhee, L. M., Ramachandran, J., Reale, V., Glencorse, T. A., Seeburg, P. H. & Barnard, E. A. (1987) Nature (London) 328, 221-227.
5. Cutting, G. R., Lu, L., O'Hara, B. F., Kasch, L. M., Montrose-Rafizadeh, C., Donovan, D. M., Shimada, S., Antonarakis, S. E., Guggino, W. B., Uhl, G. R. & Kazazian, H. H., Jr. (1991) Proc. Natl. Acad. Sci. USA 88, 2673-2677.
6. Giraudat, J., Dennis, M., Heidmann, T., Chang, J. Y. & Changeux, J.-P. (1986) Proc. Nail. Acad. Sci. USA 83, 2719-2723.
7. Imoto, K., Busch, C., Sakmann, B., Mishina, M., Konno, T., Nakai, J., Bujo, H., Mori, Y., Fukuda, K. & Numa, S. (1988) Nature (London) 335, 645-648.
8. Leonard, R. J., Labarca, C. G., Charnet, P., Davidson, N. & Lester, H. A. (1988) Science 242, 1578-1581.
9. Unwin, N. (1993) J. Mol. Biol. 229, 1101-1124.
10. Unwin, N. (1995) Nature (London) 373, 37-43.
11. Monod, J., Wyman, J. & Changeux, J.-P. (1965) J. Mol. Biol. 12, 88-118.
12. Karlin, A. (1967) J. Theor. Biol. 16, 306-320.
13. Shimada, S., Cutting, G. & Uhl, G. R. (1992) Mol. Pharmacol. 41, 683-687.
14. Feigenspan, A., Wässle, H. & Bormann, J. (1993) Nature (London) 361, 159-162.
15. Qian, H. & Dowling, J. E. (1993) Nature (London) 361, 162-164.
16. Zhang, D., Pan, Z.-H., Drideau, A. D., Zhang, X. & Lipton, S. A. (1995) Proc. Natl. Acad. Sci. USA 92, 11756-11760.
17. Gurusu, T. & Shingai, R. (1996) Biochim. Biophys. Acta 1305, 15-18.
18. Xu, M. & Akabas, M. H. (1993) J. Biol. Chem. 268, 21505-21508.
19. Xu, M, Covey, D. F. & Akabas, M. H. (1995) Biophys. J. 69, 1858-1867.
20. Akabas, M. H., Kaufmann, C., Archdeacon, P. & Karlin, A. (1994) Neuron 13, 919-927.
21. Woodward, R. M., Polenzani. L. & Miledi, R. (1993) Mol. Pharmacol. 43, 609-625.
22. Pan, Z.-H. & Lipton, S. A. (1995) J. Neurosci. 15, 2668-2679.
23. Galzi, J. L., Devillers-Thiery, A., Hussy, N., Bertrand, S., Changeux, J.-P. & Betrand, D. (1992) Nature (London) 359, 500-505.
24. Betrand, D., Galzi, J. L., Devillers-Thiery, A. Bertrand, S. & Changeux, J.-P. (1993) Proc. Natl. Acad. Sci USA 90, 6971-6975.
25. Katz, B. & Thesleff, S. (1957) J. Physiol. (London) 138, 63-80.
26. Jackson, M. B. (1984) Proc. Natl. Acad. Sci. USA 81, 3901-3904.
27. Labarca, C., Nowak, M. W., Zhang, H., Tang, L., Deshpande, P. & Lester, H. (1995) Nature (London) 376, 514-516.
28. Ohno, K., Hutchinson, D. O., Milone, M., Brengman, J. M. Bouza, C., Sine, S. & Engel, A. (1995) Proc. Natl. Acad. Sci. USA 92, 758-762.
29. Jackson, M. B. (1995) Trends Biochem. Sci. 19, 396-398.
30. Changeux, J.-P. & Edelstein, S. J. (1995) Trends Biochem. Sci. 19, 398-399.
31. Galzi, J.-L., Edelstein, S. J. & Changeux, J.-P. (1996) Proc. Natl. Acad. Sci. USA 93, 1853-1858.
32. Revah, F., Betrand, D., Galzi, J. L., Devillers-Thiery, A., Mulle, C., Hussy, N., Bertrand, S., Ballivet, M. & Changeux, J.-P. (1991) Nature (London) 353, 846-849.
33. Yakel, J. L., Lagrutta, A., Adelman, J. P. & North, R. A. (1993) Proc. Natl. Acad. Sci. USA 93, 1853-1858.
34. Filatov, G. N. & White, M. M. (1995) Mol. Pharmacol. 48, 379-384.
35. Zukin, S. R., Young, A. B. & Snyder, S. H. (1974) Proc. Natl. Acad. Sci. USA 71, 4802-4807.
36. Neubig, R. R. & Cohen, J. B. (1979) Biochemistry 18, 5464-5475.
37. Jackson, M. B. (1988) J. Pjysiol. (London) 397, 555-583.
38. Sine, S. M., Claudio, T. & Sigworth, F. J. (1990) J. Gen. Physiol. 96, 395-437.