Enhanced intestinal transepithelial antigen transport in allergic rats is mediated by IgE and CD23 (FcεRII)

Journal of Clinical Investigation

Volumn 106, Issue 7, 2000, Pages 879-886

  Yang, Ping Chang ^a   Berin, M Cecilia ^a   Yu, Linda C H ^a   Conrad, Daniel H ^b   Perdue, Mary H ^a  

^a MCMASTER UNIVERSITY   (Canada)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD23 ANTIGEN; FC RECEPTOR; HORSERADISH PEROXIDASE; IMMUNOGLOBULIN E; IMMUNOGLOBULIN E RECEPTOR;

ALLERGY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN BINDING; ANTIGEN DETECTION; ANTIGEN EXPRESSION; ARTICLE; CONTROLLED STUDY; INTESTINE CELL; INTESTINE EPITHELIUM; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR BINDING; SENSITIZATION; TRANSCYTOSIS;

EID: 0033802220     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI9258     Document Type: Article

References (33)

1. de Vries, J.E. 1994. Atopic allergy and other hypersensitivities. Curr. Opin. Immunol. 6:835-837.
2. Sampson, H.A. 1999. Food allergy Part 1: immunopathogenesis and clinical disorders. J. Allergy Clin. Immunol. 103:717-728.
3. Lessorf, M.H., Wraith, D.G., Merrett, T.G., Merreti, J., and Buisseret, P.D. 1980. Food allergy and intolerance in 100 patients: local and systemic effects. Q. J. Med. 49:259-271.
4. Knutson, T.W., et al. 1992. Intestinal anaphylaxis in man. Rapid increase in mucosal release of macromolecules and inflammatory mediators. Gastroenterology. 102:A646. (Abstr.)
5. Crowe, S.E., and Perdue, M.H. 1992. Gastrointestinal food hypersensitivity: basic mechanisms of pathophysiology. Gastroenterology. 103:1075-1095.
6. Scott, R.B., Diamant, S.C., and Gall, D.G. 1988. Motility effects of intestinal anaphylaxis in the rat. Am. J. Physiol. 255:G505-G511.
7. Neutra, M.R. 1998. Role of M cells in transepithelial transport of antigens and pathogens to the mucosal immune system. Am. J. Physiol. 274:G785-G791.
8. Strobel, S., and Mowat, A.M. 1998. Immune responses to dietary antigens: oral tolerance. Immunol. Today. 19:173-181.
9. Sanderson, I.R., and Walker, W.A. 1993. Uptake and transport of macromolecules by the intestine: possible role in clinical disorders (an update). Gastroenterology. 104:622-639.
10. Bomsell, M., Prydz, K., Parton, R.G., Gruenberg, J., and Simons, K. 1989. Endocytosis in filter-grown Madin-Darby canine kidney cells. J. Cell Biol. 109:3243-3258.
11. Perdue, M.H., Chung, M., and Gall, D.G. 1984. The effect of intestinal anaphylaxis on gut function in the rat. Gastroenterology. 86:391-397.
12. Perdue, M.H., and Gall, D.G. 1986. Intestinal anaphylaxis in the rat: jejunal response to in vitro antigen exposure. Am. J. Physiol. 250:G427-G431.
13. Forbes, D., Patrick, M., Perdue, M., Buret, A., and Gall, D.G. 1988. Intestinal anaphylaxis: in vivo and in vitro studies in the rat proximal colon. Am J. Physiol. 255:G201-G205.
14. Perdue, M.H., Masson S., Wershil, B.K., and Galli, S.J. 1991. Role of mast cells in ion transport abnormalities associated with intestinal anaphylaxis. Correction of the diminished secretory response in genetically mast cell-deficient W/W mice by bone marrow transplantation. J. Clin. Invest. 87:687-693.
15. Crowe, S.E., and Perdue, M.H. 1993. Anti-immunoglobulin E-stimulated ion transport in human large and small intestine. Gastrenterology. 105:764-772.
16. Crowe, S.E., Sestini, P., and Perdue, M.H. 1990. Allergic reactions of rat jejunal mucosa. Ion transport responses to luminal antigen and inflammatory mediators. Gastroenterology. 99:74-82.
17. Kosecka, U., Marshall, J.M., Crowe, S.E., Bienenstock, J., and Perdue, M.H. 1994. Pertussis toxin stimulates hypersensitivity and enhances nerve-mediated antigen uptake in rat intestine. Am. J. Physiol. 267:G745-G753.
18. Berin, M.C., et al. 1997. Rapid transepithelial antigen transport in rat jejunum: impact of sensitization and the hypersensitivity reaction. Gastroenterology. 113:856-864.
19. Kinet, J.P. 1999. The high-affinity IgE receptor (FcεRI): from physiology to pathology. Annu. Rev. Immunol. 17:931-972.
20. Kaiserlian, D., Lachaux A., Grosjean, I., Graber, P., and Bonnefoy, J.Y. 1993. Intestinal epithelial cells express the CD23/Fc-epsilon-RII molecule: enhanced expression in enteropathies. Immunology. 80:90-95.
21. Campbell, A.M., Vignola, A.M., Chanez, P., Godard, P., and Bousquat, J. 1994. low-affinity receptor for IgE on human bronchial epithelial cells in asthma. Immunology. 82:506-508.
22. Rao, M., Lee, W.T., and Conrad, D.H. 1999. Characterization of a monoclonal antibody directed against the murine B lymphocyte receptor for IgE. J. Immunol. 138:1845-1851.
23. Berin, M.C., et al. 1998. The influence of mast cells on pathways of antigen transport in rat intestine. J. Immunol. 161:2561-2566.
24. Crowe, S.E., and Perdue, M.H. 1993. Intestinal permeability in allergic rats: nerve involvement in antigen-induced changes. Am. J. Physiol. 264:G617-G623.
25. Perdue, M.H. 1999. The mucosal antigen barrier: crosstalk with mucosal cytokines. Am. J. Physiol. 277:G1-G5.
26. Belut, D., Moneret-Vautrin, D.A., Nicholas, J.P., and Grilliat, J.P. 1980. IgE levels in intestinal juice. Dig. Dis. Sci. 25:323-332.
27. Negrao-Correa, D., Adams, L.S., and Bell, R.G. 1996. Intestinal transport and catabolism of IgE: a major blood-independent pathway of IgE dissemination during a Trichinella spiralis infection of rats. J. Immunol. 157:4037-4046.
28. Ramaswamy, K., Hakimi, J., and Bell, R.G. 1994. Evidence for an interleukin-4-inducible immunoglobulin E uptake and transport mechanism in the intestine. J. Exp. Med. 180:1793-1803.
29. Conrad, D.H., Campbell, K.A., Barrlett, W.C., Squire, C.M., and Dierks, S.E. 1994. Structure and function of the low-affinity IgE receptor. Adv. Exp. Med. Biol. 347:17-30.
30. Richards, M.L., and Katz, D.H. 1994. Regulation of the murine FcεRII (CD23) gene. Functional characterization of an IL-4 enhancer element. J. Immunol. 152:3453-3466.
31. Hauer, A.C., Breese, E.J., Walker-Smith, J.A., and MacDonald, T.T. 1997. The frequency of cells secreting interferon-γ and interleukin-4,-5, and - 10 in the blood and duodenal mucosa of children with cow's milk hypersensitivity. Pediatr. Res. 42:629-638.
32. Hashimoto, S., et al. 1993. Elevation of soluble IL-2 receptor and IL-4, and non-elevation of IFNγin sera from patients with allergic asthma. Ann. Allergy. 71:455-458.
33. Yokata, A, et al. 1992. Two forms of the low affinity Fc receptor for IgE differentially mediate endocytosis and phagocytosis: identification of the critical cytoplasmic domains. Proc. Natl. Acad. Sci. USA. 89:5030-5034.