Immune Reconstitutioim and Stem Cell Sources

Pediatric Pathology and Molecular Medicine

Volumn 19, Issue 42038, 2000, Pages 187-203

  Smith, Franklin O ^a   Thomson, Blythe G ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

bone marrow transplantation; immune reconstitution

Indexed keywords

CD16 ANTIGEN; CD19 ANTIGEN; CD20 ANTIGEN; CD3 ANTIGEN; CD34 ANTIGEN; CD4 ANTIGEN; CD45 ANTIGEN; CD56 ANTIGEN; CD8 ANTIGEN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; INTERLEUKIN 7; SOMATOMEDIN C; T LYMPHOCYTE RECEPTOR;

AGE; ARTICLE; B LYMPHOCYTE; BACTERIOPHAGE PHI X 174; BONE MARROW TRANSPLANTATION; GRAFT VERSUS HOST REACTION; HELPER CELL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HLA MATCHING; HUMAN; IMMUNE RESPONSE; IMMUNOGLOBULIN PRODUCTION; INFECTION; LYMPHOCYTE DEPLETION; NATURAL KILLER CELL; PERIPHERAL BLOOD STEM CELL; PRIORITY JOURNAL; T LYMPHOCYTE; UMBILICAL CORD BLOOD;

EID: 0033798049     PISSN: 15227952     EISSN: None     Source Type: Journal    
DOI: 10.1080/15513810009168633     Document Type: Article

References (67)

1. Kernan N A, Bartsch G, Ash R C, et al. Analysis of 462 transplantations from unrelated donors facilitated by the National Marrow Donor Program. N Engl J Med 1993; 328: 593 – 602
2. Marks D I, Cullis J O, Ward K N, et al. Allogeneic bone marrow transplantation for chronic myelogenous leukemia using sibling and volunteer unrelated donors. A comparison of complications in the first 2 years. Ann Intern Med 1993; 119: 207 – 214
3. Clift R A, Buckner C D, Thomas E D, et al. Marrow transplantation for chronic myeloid leukemia: a randomized study comparing cyclophosphamide and total body irradiation with busulfan and cyclophosphamide. Blood 1994; 84: 2036 – 2043
4. Davies S M, Shu X O, Blazer B R, et al. Unrelated donor bone marrow transplantation: influence of HLA-A and -B incompatibility on outcome. Blood 1995; 86: 1636 – 1642
5. Casper J, Camitta B, Truitt R, et al. Unrelated bone marrow transplants for children with leukemia or myelodysplasia. Blood 1995; 85: 2354 – 2363
6. Ochs L, Shu X O, Miller J, et al. Late infections after allogeneic bone marrow transplantation: comparison of incidence in related and unrelated donor transplant recipients. Blood 1995; 86: 3979 – 3986
7. Oakhill A, Pamphilon D H, Potter M N, et al. Unrelated donor bone marrow transplantation for children with relapsed acute lymphoblastic leukemia in second remission. Br J Haematol 1996; 94: 574 – 578
8. Chown S R, Marks D I, Cornish J M, Pamphilon D H, Potter C G, Steward C G, Oakhill A. Unrelated donor bone marrow transplantation in children and young adults with acute myeloid leukaemia in remission. Br J Haematol 1997; 99: 36 – 40
9. Hongeng S, Krance R A, Bowman L C, et al. Outcome of transplantation with matched sibling and unrelated donor bone marrow in children with leukemia. Lancet 1997; 350: 767 – 771
10. Davies S M, Wagner J E, Shu X O, et al. Unrelated donor bone marrow transplantation for children with acute leukemia. J Clin Oncol 1997; 15: 557 – 565
11. Mattsson J, Ringden O, Aschan J, et al. A low incidence of grade II to IV GVHD, but high mortality from infection using HLA-A, -B, and -DR identical unrelated donors and immunosuppression with ATG, cyclosporine, and methotrexate. Transplant Proc 1997; 29: 735 – 736
12. Small T N, Avigan D, Dupont B, et al. Immune reconstitution following T-cell depleted bone marrow transplantation: effect of age and post-transplant graft rejection. Biol Blood Marrow Transplant 1997; 3: 65 – 75
13. Soifer R J, Fairclough D, Robertson M, et al. CD6-depleted allogeneic bone marrow transplantation for acute leukemia in first complete remission. Blood 1997; 89: 3039 – 3047
14. Hansen J A, Gooley T A, Martin P J, Appelbaum F, Chauncey T F, Clift R E, Petersdorf E W. Bone marrow transplantation from unrelated donors for patients with chronic myeloid leukemia N Engl J Med 1998; 338: 962 – 968
15. Ault K, Antin J, Ginsburg D, et al. Phenotype of recovering cell populations after bone marrow transplantation. J Exp Med 1985; 161: 1483 – 1502
16. Lum L. The kinetics of immune reconstitution after human bone marrow transplantation. Blood 1987; 69: 369 – 380
17. Small T N, Papadopoulos E B, Boulad F, et al. Comparison of immune reconstitution after unrelated and related T-cell depleted bone marrow transplantation: effect of patient age and donor leukocyte infusion. Blood 1999; 93: 467 – 480
18. Lamb L S, Gee A P, Henslee-Downey P J, et al. Phenotypic and functional reconstitution of peripheral blood lymphocytes following T cell-depleted bone marrow transplantation from partially mismatched related donors. Bone Marrow Transplant 1998; 21: 461 – 471
19. Kook H, Goldman F, Padley D, et al. Reconstitution of the immune system after unrelated or partially matched T-cell-depleted bone marrow transplantation in children: immunophenotypic analysis and factors affecting the speed of recovery. Blood 1996; 88: 1089 – 1097
20. Haynes B F, Denning S M, Singer K H, Kurtzberg J. Ontogeny of T-cell precursors: a model for the initial stages of human T-cell development. Immunol Today 1989; 10: 87 – 91
21. Parkman R, Weinberg K I. Immunological reconstitution following hematopoietic stem cell transplantation. Bone Marrow Transplantation, S J Forman, K G Blume, E D Thomas. Blackwell Sciences, Maiden, MA 1999; 704 – 711
22. Marrack P, Lo D, Brinster R, et al. The effect of thymus environment on T cell development and tolerance. Cell 1988; 53: 627 – 634
23. Sha W C, Nelson C A, Newberry R D, et al. Positive and negative selection of an antigen receptor on T cells in transgenic mice. Nature 1988; 336: 73 – 76
24. Zuniga-Pflucker J C, Longo D L, Kruisbeek A M. Positive selection of CD4–8+ T cells in the thymus in transgenic mice. Nature 1988; 338: 76 – 78
25. Sanders M E, Makgoba M W, Shaw S. Human naive and memory T cells: Rein-terpretation of helper-inducer and suppressor-inducer subsets. Immunol Today 1988; 9: 195 – 199
26. Akbar A N, Salmon M, Janossy G. The synergy between naive and memory T cells during activation. Immunol Today 1991; 12: 184 – 188
27. Spits H, Lanier L L, Phillips J H. Development of human T and natural killer cells. Blood 1995; 85: 2654 – 2670
28. Akbar A N, Terry L, Timms A, et al. Loss of CD45R and gain of UCHL1 reactivity is a feature of primed T cells. J Immunol 1988; 140: 2171 – 2178
29. Mackay C R. T-cell memory: the connection between function, phenotype and migration pathways. Immunol Today 1991; 12: 189 – 192
30. Clement L T. Isoforms of the CD45 common leukocyte antigen family: markers of human T-cell differentiation. J Clin Immunol 1992; 12: 1 – 10
31. Roberts M M, To L B, Gillis D, et al. Immune reconstitution following peripheral blood stem cell transplantation. Bone Marrow Transplant 1993; 12: 469 – 475
32. Foot A BM, Potter M N, Donaldson C, et al. Immune reconstitution after BMT in children. Bone Marrow Transplant 1993; 11: 7 – 13
33. Ottinger H D, Beelen D W, Scheulen B, et al. Improved immune reconstitution after allotransplantation of peripheral blood stem cells instead of bone marrow. Blood 1996; 88: 2775 – 2779
34. Talmadge J E, Reed E, Ino K, et al. Rapid immunologic reconstitution following transplantation with mobilized peripheral blood stem cells compared to bone marrow. Bone Marrow Transplant 1996; 19: 161 – 172
35. Martinez C, Urbano-Ispizua A, Rozman C, et al. Immune reconstitution following allogeneic peripheral blood progenitor cell transplantation: comparison of recipients of positive CD34+ selected grafts with recipients of unmanipulated grafts. Exp Hematol. 1999; 27: 561 – 568
36. Locatelli F, Maccario R, Comoli P, et al. Hematopoietic and immune recovery after transplantation of cord blood progenitor cells in children. Bone Marrow Transplant 1996; 18: 1095 – 1101
37. Behringer D, Bertz Schmoor C, Berger C, Dwenger A, Finke J. Quantitative lymphocyte subset reconstitution after allogeneic hematopoietic transplantation from matched related donors with CD34+ selected grafts, unselected PBPC grafts or BM grafts. Bone Marrow Transplant 1999; 24: 295 – 302
38. Heitger A, Neu N, Kern H, et al. Essential role of the thymus to reconstitute naive (CD45RA +) T-helper cells after human allogeneic bone marrow transplantation. Blood 1997; 90: 850 – 857
39. Favrot M, Janossy G, Tidman N, et al. T cell regeneration after allogeneic bone marrow transplantation. Clin Exp Immunol 1983; 54: 59 – 72
40. Storek J, Witherspoon R P, Storb R. T cell reconstitution after bone marrow transplantation does not resemble T cell development in early life. Bone Marrow Transplant 1995; 16: 413 – 425
41. Bengtsson M, Totterman T H, Smedmyr B, et al. Regeneration of functional and activated NK and T-cell subset cells in the marrow and blood after autologous bone marrow transplantation: a prospective phenotypic study with 2/3 color FACS analysis. Leukemia 1989; 3: 68 – 75
42. Leino L, Lilius E M, Nikoskelainen J, et al. The reappearance of 10 differentiation antigens on peripheral blood lymphocytes after allogeneic bone marrow transplantation. Bone Marrow Transplant 1991; 8: 339 – 344
43. Keever C A, Small T N, Flomenberg N, et al. Immune reconstitution following bone marrow transplantation: comparison of recipients of T-cell depleted marrow with recipients of conventional marrow grafts. Blood 1989; 73: 1340 – 1350
44. Friedrich W, O'Reilly R J, Kozinger B, Gebhard D R, Good R A, Evans R L. T-lymphocyte reconstitution in recipients of bone marrow transplants with and without GVHD: imbalances of T cell subpopulations have unique regulatory and cognitive functions. Blood 1982; 59: 696 – 701
45. Kurtzberg J, Laughlin M, Graham M L, et al. Placental blood as a source of hematopoietic stem cells for transplantation into unrelated recipients. N Engl J Med 1996; 335: 157 – 166
46. Weinberg K, Annett G, Kashyap A, et al. The effect of thymic function on immunocompetence following bone marrow transplantation. Biol Blood Marrow Transplant 1995; 1: 18 – 23
47. Seddick M, Seemayer T A, Lapp W S. T cell functional defects associated with thymic epithelial cell injury induced by graft-versus-host reaction. Transplantation 1980; 29: 61 – 66
48. Seddick M, Seemayer T A, Lapp W S. The graft-versus-host reaction and immune function. Transplantation 1984; 37: 281 – 286
49. Graze P R, Gale R P. Chronic graft versus host disease: a syndrome of disordered immunity. Am J Med 1979; 66: 611 – 620
50. Witherspoon R P, Kopecky K, Storb R F, et al. Immunological recovery in 48 patients following syngeneic marrow transplantation for hematological malignancy. Transplantation 1982; 33: 143 – 149
51. O'Reilly R J, Small T N, Papadopoulos E, et al. Biology and adoptive cell therapy of Epstein-Barr virus-associated lymphoproliferative disorders in recipients of marrow allografts. Immunol Rev 1997; 157: 195 – 216
52. Papadopoulos E B, Ladanyi M, Emanuel D, et al. Infusions of donor leukocytes to treat Epstein-Barr-associated lymphoproliferative disorders after allogeneic bone marrow transplantation. N Engl J Med 1994; 330: 1185 – 1191
53. Rooney C M, Smith C A, Hg C YC, et al. Use of gene-modified virus-specific T lymphocytes to control Epstein-Barr-related lymphoproliferation. Lancet 1995; 345: 9 – 13
54. Heslop H E, Hg C YC, Congfen L, et al. Long-term restoration of immunity against Epstein-Barr virus infection by adoptive transfer of gene-modified virus-specific T lymphocytes. Nature Med 1996; 2: 551 – 555
55. Quinnan G V, Kirmani N, Rook A H, et al. Cytotoxic T cells in cytomegalovirus infection: HLA-restricted T-lymphocyte and non-T-lymphocyte cytotoxic responses correlate with recovery from cytomegalovirus infection in bone-marrow-transplant recipients. N Engl J Med 1982; 307: 7 – 13
56. Reusser P, Riddell S R, Meyers J D, Greenberg P D. Cytotoxic T-lymphocyte response to cytomegalovirus after human allogeneic bone marrow transplantation: pattern of recovery and correlation with cytomegalovirus infection and disease. Blood 1991; 78: 1373 – 1380
57. Li C R, Greenberg P D, Gilbert M J, et al. Recovery HLA-restricted cytomegalovirus (CMV)-specific T-cell responses after allogeneic bone marrow transplant: correlation with CMV disease and effect of ganciclovir prophylaxis. Blood 1994; 83: 1971 – 1979
58. Walter E A, Greenberg P D, Gilbert M J, et al. Reconstitution of cellular immunity against cytomegalovirus in recipients of allogeneic bone marrow transfer of T-cell clones from the donor. N Engl J Med 1995; 333: 1038 – 1044
59. Hromas R, Cornetta K, Srour E, et al. Donor leukocyte infusion as therapy of life-threatening adenoviral infection after T-cell-depleted marrow transplantation. Blood 1994; 84: 1689 – 1690
60. Bolotin E, Annett G, Parkman R, Weinberg K. Serum levels of IL-7 in bone marrow transplant recipients: relationship to clinical characteristics and lymphocyte count. Bone Marrow Transplant 1999; 23: 783 – 788
61. Or R, Abdul-Hai A, Ben-Yehuda A. Reviewing the potential utility of interleukin-7 as a promotor of thymopoiesis and immune revcovery. Cytokines, Cell Mol Therapy 1998; 4: 287 – 294
62. Abdul-Hai A, Ben-Yehuda A, Weiss L, Freidman G, Zakay-Rones Z, Slavin S, Or R. Interleukin-7-enhanced cytotoxic T lymphocyte activity after viral infection in marrow transplanted mice. Bone Marrow Transplant 1997; 19: 539 – 543
63. Abdul-Hai A, Or R, Slavin S, Friedman G, Weiss L, Matsa D, Ben-Yehuda A. Stimulation of immune reconstitution by interleukin-7 after syngeneic bone marrow transplantation in mice. Exp Hematol 1996; 24: 1416 – 1422
64. Bolotin E, Smogorzewska M, Smith S, Widmer M, Weinberg K. Enhancement of thymopoiesis after bone marrow transplant by in vivo interleukin-7. Blood 1996; 88: 1887 – 1894
65. Montecino-Rodriquez E, Clark R, Dorshkind K. Effects of insulin-like growth factor administration and bone marrow transplantation on thymopoiesis in aged mice. Endocrinology 1998; 139: 4120 – 4126
66. Montecino-Rodriquez E, Clark R, Johnson A, Collins L, Dorshkind K. Defective B cell development in Snell dwarf (dw/dw) mice can be corrected by thyroxine treatment. J Immunol 1996; 157: 3334 – 3340
67. Modigliani Y, Coutinho A, Pereira P. et al. Establishment of tissue-specific tolerance is driven by regulatory T cells selected by thymic epithelium. Eur J Immunol 1996; 26: 1807 – 1815