Immune reconstitution following allogeneic peripheral blood progenitor cell transplantation: Comparison of recipients of positive CD34+ selected grafts with recipients of unmanipulated grafts

Experimental Hematology

Volumn 27, Issue 3, 1999, Pages 561-568

  Martínez, Carmen ^a   Urbano Ispizua, Alvaro ^a   Rozman, Ciril ^a   Marín, Pedro ^a   Rovira, Montserrat ^a   Sierra, Jorge ^a   Montfort, Nuria ^a   Carreras, Enric ^a   Montserrat, Emilio ^a  

^a Postgraduate School of Hematology Farreras Valentí   (Spain)

Author keywords

Allogeneic transplantation; Immune reconstitution; Peripheral blood progenitor cells

Indexed keywords

CYCLOPHOSPHAMIDE; CYCLOSPORIN A; METHOTREXATE; METHYLPREDNISOLONE;

ADULT; ALLOTRANSPLANTATION; ARTICLE; CELL SELECTION; CLINICAL ARTICLE; FEMALE; GRAFT VERSUS HOST REACTION; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; LEUKAPHERESIS; LYMPHOCYTE DEPLETION; MALE; PERIPHERAL BLOOD STEM CELL; PRIORITY JOURNAL; STEM CELL TRANSPLANTATION; T LYMPHOCYTE ACTIVATION; WHOLE BODY RADIATION;

ADOLESCENT; ADULT; ANTIGENS, CD19; ANTIGENS, CD34; ANTIGENS, CD4; ANTIGENS, CD45; ANTIGENS, CD8; B-LYMPHOCYTE SUBSETS; CELL SEPARATION; CHIMERA; CYCLOPHOSPHAMIDE; CYCLOSPORINE; FEMALE; GRAFT SURVIVAL; GRAFT VS HOST DISEASE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; IMMUNOPHENOTYPING; INFECTION; KILLER CELLS, NATURAL; KINETICS; LEUKAPHERESIS; LYMPHOCYTE COUNT; LYMPHOCYTE DEPLETION; LYMPHOCYTE SUBSETS; MALE; METHOTREXATE; METHYLPREDNISOLONE; MIDDLE AGED; PROSPECTIVE STUDIES; T-LYMPHOCYTE SUBSETS; TIME FACTORS; TRANSPLANTATION CONDITIONING; WHOLE-BODY IRRADIATION;

EID: 0344923782     PISSN: 0301472X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0301-472X(98)00029-0     Document Type: Article

References (53)

1. Goldman J. Peripheral blood stem cells for allografting. Blood. 85:1995;1413.
2. Bensinger W.I., Weaver C.H., Appelbaum F.R., Rowley S., Demirer T., Sanders J., Storb R., Buckner C.D. Transplantation of allogeneic peripheral blood stem cells mobilized by recombinant human granulocyte colony-stimulating factor. Blood. 85:1995;1655.
3. Schmitz N., Dreger P., Suttorp M., Rohwedder E.B., Haferlach T., Löeffler H., Hunter A.E., Russell N.H. Primary transplantation of allogeneic peripheral blood progenitor cells mobilized by filgrastim (granulocyte colony-stimulating factor). Blood. 85:1995;1666.
4. Russell N.H., Hunter A.E. Peripheral blood stem cells for allogeneic transplantation. Bone Marrow Transplant. 13:1994;353.
5. dim) and lymphoid subsets, and possible predictors of engraftment and graft-versus-host-disease Blood. 86:1995;2842.
6. Pavletic Z., Bishop M., Tarantolo S., Martin-Algarra S., Bierman P., Vose J., Reed E., Gross T., Kollath J., Nasrati K., Jackson J., Armitage J.et al. Hematopoietic recovery after allogeneic blood stem-cell transplantation compared with bone marrow transplantation in patients with hematologic malignances. J Clin Oncol. 15:1997;1608.
7. Ottinger H.D., Beelen D.W., Scheulen B., Schaefer U.W., Grosse-Wilde H. Improved immune reconstitution after allotransplantation of peripheral blood stem cells instead of bone marrow. Blood. 88:1996;2775.
8. Egner W., Price P., Sizer G., Bass G., Brown D., Marus R. Immune reconstitution after peripheral blood stem cell transplants. Br J Hematol. 97:1997;35(abstr).
9. Pavletic Z.S., Bishop M.R., Joshi S.S., Tarantolo S.R., Pirruccello S.J., Reed E.C., Bierman P.J., Vose J.M., Gross T.G., Kollath J., Nasrati K., Armitage J.O.et al. Immunologic reconstitution after allogeneic blood stem cell transplantation. faster lymphocyte recovery correlates with better survival Blood. 88:1996;422a(abstr).
10. Storek J., Witherspoon R.P., Maloney D.G., Chauncey T.R., Storb R. Improved reconstitution of CD4 T cells and B cells but worsened reconstitution of serum IgG levels after allogeneic transplantation of blood stem cells instead of marrow. Blood. 89:1997;3891.
11. Parkman R. Immunological reconstitution following bone marrow transplantation. (1994) In: Farman SJ, Blume KG, Thomas ED (eds.) Bone marrow transplantation. Boston: Blackwell Scientific Publications, pp. 504-512.
12. Storek J., Witherspoon R.P., Storb R. T cell reconstitution after bone marrow transplantation into adult patients does not resemble T cell development in early life. Bone Marrow Transplant. 16:1995;413.
13. Small T., Keever C., Weiner-Fedus S. B-cell differentiation following autologous, conventional, or T-cell depleted bone marrow transplantation. a recapitulation of normal B-cell ontogeny Blood. 76:1990;1647.
14. De Gast G.C., Verdonck L.F., Middeldorp J.M. Recovery of T cell subsets after autologous bone marrow transplantation is mainly due to proliferation of mature T cells in the graft. Blood. 66:1985;428.
15. Mackall C., Granger L., Sheard M., Cepeda R., Gress R. T-cell regeneration after bone marrow transplantation. differential CD45 isoform expression on thymic-derived versus thymic-independent progeny Blood. 82:1993;2585.
16. Weaver C.H., Longin K., Buckner C.D., Bensinger W. Lymphocyte content in peripheral blood mononuclear cells collected after administration of recombinant granulocyte colony stimulating factor. Bone Marrow Transplant. 13:1994;411.
17. Martínez C., Urbano-Ispizua A., Rozman C., Marín P., Mazzara R., Carreras E., Rovira M., Sierra J., Briones J., Ordinas A., Montserrat E. Effects of G-CSF administration and peripheral blood progenitor cell collection in 20 healthy donors. Ann Hematol. 72:1996;269.
18. Appelbaum F.R. Allogeneic bone marrow transplantationfor malignancy - current problems and prospects for improvement. Magrath I. New directions in cancer treatment. 1989;Springer-Verlag, New York. 143p.
19. Van Bekkum D (1985) Graft-versus-host disease. In: van Bekkum DW, Lwenberg B (eds.) Bone marrow transplantation: biological mechanisms and clinical practice. New York: Dekker, p. 147.
20. Majolino I., Saglio G., Scime R., Serra A., Cavallero A.M., Fiandaca T., Vasta S., Pampinella M., Catania P., Indovina A., Marceno R., Santoro A. High incidence of chronic GVHD after primary allogeneic peripheral blood stem cell transplantation in patients with hematological malignancies. Bone Marrow Transplant. 17:1996;555.
21. Anderlini P., Przepiorka D., Khouri I., van Beslen K., Mehra R., Giralt S., Gajewski J., Cleary K., Champlin R.E., Andersson B., Korbling M. Chronic graft-versus-host disease (GVHD) after allogeneic marrow or blood stem cell transplantation. Blood. 86:1995;108a(abstr).
22. Urbano-Ispizua A., García-Conde J., Brunet S., Hernández F., Sanz G., Alegre A., Petit J., Bargay J., Vivancos P., Solano C., Ojeda E., Domingo A.et al. High incidence of chronic GVHD after allogeneic peripheral blood progenitor cell transplantation from matched related donors. Blood. 88:1996;617a(abstr).
23. Foot A.B.M., Potter M.N., Donalson C., Cornish J.M., Wallington T.B., Oakhill A., Pamphilon D.H. Immune reconstitution after BMT in children. Bone Marrow Transplant. 11:1993;7.
24. Keever C., Small T., Flomenberg N., Heller G., Pekle K., Black P., Pecora A., Gillio A., Kernan N., O'Reilly R. Immune reconstitution following bone marrow transplantation. comparison of recipients of T-cell depleted marrow with recipients of conventional marrow grafts Blood. 73:1989;1340.
25. Parreira A., Smiyh J., Hows J., Smithers S., Apperley J., Rombos Y., Goldman J., Gordon-Smith E., Catovsky D. Immunological reconstitution after bone marrow transplant with Campath-1 treated bone marrow. Clin Exp Immunol. 67:1987;142.
26. Craston R., Lowdell M., Ray N., Koh M., Prentice G. Immune reconstitution after T cell depleted allogeneic bone marrow transplant. Br J Hematol. 97:1997;40(abstr).
27. Janossy G., Prentice H.G., Grob J.P., Ivory K., Tidman N., Grundy J., Favrot M., Brenner M.K., Campana D., Blacklock A., Gilmore M.J., Patterson J.et al. T lymphocyte regeneration after transplantation of T cell depleted allogeneic bone marrow. Clin Exp Immunol. 63:1986;577.
28. Kook H., Goldman F., Padley D., Giller R., Rumelhart S., Holida M., Lee N., Peters C., Comito M., Huling D., Trigg M. Reconstruction of the immune system after unrelated or partially matched T-cell-depleted bone marrow transplantation in children. immunophenotypic analysis and factors affecting the speed of recovery Blood. 88:1996;1089.
29. Bridge J., Tsakalakis C., Mackinnon S., Kaminski E., Hows J. Immune reconstitution after BMT with or without campath-1-M treatment of HLA identical sibling or unrelated donor marrow. Bone Marrow Transplant. 5:1990;111(abstr).
30. Finke J., Behringer D., Bertz H., Berger C., Potthoff K., Winfler J., Hardung M., Mertelsmann R. Comparison of immune reconstitution and GVHD after allogeneic peripheral blood stem cell transplantation with or without CD34+ selection. Blood. 88:1996;616a(abstr).
31. Urbano-Ispizua A., Rozman C., Martínez C., Marín P., Briones J., Rovira M., Féliz P., Viguria M.C., Merino A., Sierra J., Mazzara R., Carreras E.et al. Rapid engraftment without significant graft-versus-host disease after allogeneic transplantation of CD34+ selected cells from peripheral blood. Blood. 89:1997;3967.
32. Thomas E.D., Storb R., Clift R.A., Fefer M., Johnson F.L., Neiman P.F., Lerner K.G., Glucksberg H., Buckner C.D. Bone marrow transplantation. N Engl J Med. 292:1975;832.
33. Briones J., Urbano-Ispizua A., Rozman C., Marín P., Carreras E., Rovira M., Sierra J., Colomer D., Martínez C., Montserrat E. Study of hematopoietic chimerism following allogeneic peripheral blood stem cell transplantation using PCR amplification of short tandem repeats. Ann Hematol. 72:1996;265.
34. Vacca A., Felli M.P., Farina A.R., Martinotti S., Maroder M., Screpanti I., Meco D., Pentrangeli E., Frati L., Gulino A. Glucocorticoid receptor-mediated suppression of the interleukin 2 gene expression through impairment of the cooperativity between nuclear factor of activated T cells and AP-1 enhancer elements. J Exp Med. 175:1992;637.
35. Fernandez-Ruiz E., Rebollo A., Nieto M.A. IL-2 protects T cells hybrids from the cytolytic effect of glucocorticoids. Synergistic effect of IL-2 and dexamethasone in the induction of high-affinity IL-2 receptors. J Immunol. 143:1989;4146.
36. Lanza L., Scudeletti M., Puppo F., Bosco O., Peirano L., Filaci G., Fecarotta E., Vidali G., Indiveri F. Prednisone increases apoptosis in in vitro activated human peripheral blood T lymphocytes. Clin Exp Immunol. 103:1996;482.
37. Mackall C., Fleisher T., Brown M., Andrich M., Chen C., Feuerstein I., Horowitz M., Magrath I., Shad A., Steinberg S., Wexler L., Gress R. Age, thymopoiesis, and CD4+ T-lymphocyte regeneration after intensive chemotherapy. N Engl J Med. 332:1995;143.
38. Small T., Avigan D., Dupont B. Immune reconstitution following T-cell depleted bone marrow transplantatino. effect of age and posttransplant graft rejection prophylaxis Biol Blood Marrow Transplant. 3:1997;65.
39. Atkinson K. Reconstruction of the haemopoietic and immune systems after marrow transplantation. Bone Marrow Transplant. 5:1990;209.
40. Favrot M., Janossy G., Tidman N., Blacklock H., Lopez E., Bofill M., Lampert I., Morgenstein G., Powles R., Prentice G., Hoffbrand A. T cell regeneration after allogeneic bone marrow transplantation. Clin Exp Immunol. 54:1983;59.
41. Mackall C., Fleisher T., Brown M., Andrich M., Chen C., Feuerstein I., Magrath I., Wexler L., Dimitrov D., Gress R. Distinctions between CD8+ and CD4+ T-cell regenerative pathways result in prolonged T-cell subset imbalanced after intensive chemotherapy. Blood. 89:1997;3700.
42. Gratama J.W., Fibbe W.E., Naipal A.M., Slats J., Stijnen T., D'Amaro J., Bolhuis R.L., The T.H., Janssen J. Cytomegalovirus immunity and T lymphocytes in bone marrow donors and acute graft-versus-host disease. Bone Marrow Transplant. 2:1986;141.
43. Schroff R.W., Gale R.P., Fahey J.L. Regeneration of T cell subpopulations after bone marrow transplantation. cytomegalovirus infection and lymphoid subset imbalance J Immunol. 129:1982;1926.
44. Kawanishi Y., Passweg J., Drobyski W.R., Rowlins P., Cook-Craig A., Casper J., Pietryga D., Garbrecht F., Camitta B., Horowitz M., Juckett M., Margolis D.et al. Effect of T cell subset dose on outcome of T cell-depleted bone marrow transplantation. Bone Marrow Transplant. 19:1997;1069.
45. Blazar B.R., Taylor P.A., Panoskaltsis-Mortari A., Barrett T.A., Bluestone J.A., Vallera D.A. Lethal murine graft-versus-host disease induced by donor γ/δ expressing T cells with specificity for host nonclassical major histocompatibility complex class Ib antigens. Blood. 87:1996;827.
46. Blazar B.R., Taylor P.A., Bluestone J.A., Vallera D.A. Murine γ/δ-expressing T cells affect alloengraftment via the recognition of nonclassical major histocompatibility complex class Ib antigens. Blood. 87:1996;4463.
47. Velardi A., Speranza C., Terenzi A. Acquisition of Ig isotype diversity after bone marrow transplantation in adults. A recapitulation of normal B-cell ontogeny. J Immunol. 141:1988;815.
48. Noel D.R., Witherspoon R.P., Storb R., Atkinson K., Doney K., Mickelson E.M., Ochs H.D., Warren R.P., Weiden P.L., Thomas E.D. Does graft-versus-host disease influence the tempo of immunologic recovery after allogeneic human marrow transplantation? An observation on 56 long-term survivors. Blood. 51:1978;1087.
49. Witherspoon R.P., Kopecky K., Storb R., Flournoy N., Sullivan K.M., Sosa R., Deeg H.J., Ochs H.S., Cheever M.A., Fefer A., Thomas E.D. Immunological recovery in 48 patients following syngeneic marrow transplantation for hematological malignancy. Transplantation. 33:1982;143.
50. Storek J., Saxon A. Reconstitution of B cell immunity following bone marrow transplantation. Bone Marrow Transplant. 9:1992;395.
51. Talmadge J.E., Reed E., Ino K., Kenssinger A., Kuszynski C., Heimann D., Varney M., Jackson J., Vose J.M., Bierman P.J. Rapid immunologic reconstitution following transplantation with mobilized peripheral blood stem cells as compared to bone marrow. Bone Marrow Transplant. 19:1997;161.
52. Rosillo M.C., Ortuño F., Moraleda J.M., Lozano M.L., Heras I., De Arriba F., Vicente V. Immune recovery after autologous or rhG-CSF primed PBSC transplantation. Eur J Haematol. 56:1996;301.
53. To L.B., Haybck D.N., Dowse T., Simmons P.J., Trimboli S., Ashman L.K., Juttner C.A. A comparative study of the phenotype and proliferative capacity of peripheral blood CD34+ cells mobilized by four different protocols and those of steady-phase PB and bone marrow CD34+ cells. Blood. 84:1994;2930.