Insights into modulation of (and by) growth hormone signaling

Journal of Laboratory and Clinical Medicine

Volumn 136, Issue 1, 2000, Pages 14-20

  Frank, Stuart J ^a,b,c,d,e   Messina, Joseph L ^a,b,c,d,e   Baumann, Gerhard ^a,b,c,d,e   Black, Roy A ^a,b,c,d,e   Bertics, Paul J ^a,b,c,d,e  

^a University of Alabama at Birmingham   (United States)

^b BIRMINGHAM VA MEDICAL CENTER   (United States)

^c NORTHWESTERN UNIVERSITY   (United States)

^d AMGEN INC   (United States)

^e UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0033797583     PISSN: 00222143     EISSN: None     Source Type: Journal    
DOI: 10.1067/mlc.2000.107300     Document Type: Conference Paper

References (27)

1. Molecular mechanism of growth hormone action
2. Recent advances in cytokine signal transduction: Lessons from growth hormone and other cytokines
3. Interaction of the growth hormone receptor cytoplasmic domain with the JAK2 tyrosine kinase
4. Regions of the JAK2 tyrosine kinase required for coupling to the growth hormone receptor
5. Disulfide linkage of growth hormone (GH) receptors (GHR) reflects GH-induced GHR dimerization. Association of JAK2 with the GHR is enhanced by receptor dimerization
6. Growth hormone receptor cytoplasmic domain differentially promotes tyrosine phosphorylation of STAT5b and STAT3 by activated JAK2 kinase
7. Growth hormone (GH) insensitivity due to primary GH receptor deficiency
8. A mammalian model for Laron syndrome produced by targeted disruption of the mouse growth hormone receptor/binding protein gene (the Laron mouse)
9. Insulin inhibits growth hormone signaling via the growth hormone receptor/JAK2/STAT5B pathway
10. The circulating growth hormone (GH)-binding protein complex: A major constituent of plasma GH in man
11. ADAMs: Focus on the protease domain
12. Blockade of growth hormone receptor shedding by a metalloprotease inhibitor
13. Human growth hormone-stimulated growth of human cultured lymphocytes (IM-9) and its inhibition by phorbol diesters through down-regulation of the hormone receptors. Possible involvement of phosphorylation of a 55,000 molecular weight protein associated with the receptor in the down-regulation
14. Sensitivity of growth hormone receptor proteolysis and growth hormone binding protein shedding to inhibitors of MEK1
15. Distinct cytoplasmic domains of the growth hormone receptor are required for glucocorticoid- and phorbol ester-induced decreases in growth hormone (GH) binding. These domains are different from that reported for GH-induced receptor internalization
16. Involvement of the Src homology 2-containing tyrosine phosphatase SHP-2 in growth hormone signaling
17. Insulin receptor substrate-1 enhances growth hormone-induced proliferation
18. Insulin receptor substrate-1-mediated enhancement of growth hormone-induced MAP kinase activation
19. Growth hormone attenuation of epidermal growth factor-induced mitogenesis
20. Growth hormone-induced alteration in ErbB-2 phosphorylation status in 3T3-F442A fibroblasts
21. Tyrosine phosphorylation of the EGF receptor by the kinase Jak2 is induced by growth hormone
22. Identification of SH2-B beta as a potent cytoplasmic activator of the tyrosine kinase Janus kinase 2
23. Mapping of a cytoplasmic domain of the human growth hormone receptor that regulates rates of inactivation of Jak2 and Stat proteins
24. SOCS/CIS protein inhibition of growth hormone-stimulated STAT5 signaling by multiple mechanisms
25. Dual effects of suppressor of cytokine signaling (SOCS-2) on growth hormone signal transduction
26. CIS desensitizes GH induced Stat5 signaling in rat liver cells
27. Mechanism of inhibition of growth hormone receptor signaling by suppressor of cytokine signaling proteins