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Volumn 14, Issue 5, 2000, Pages 533-542

Inhibition of nitric oxide synthesis induces coronary vascular remodeling and cardiac hypertrophy associated with the activation of p70 S6 kinase in rats

Author keywords

ACE inhibitor; Hydralazine; L NAME; Protein synthesis; Rapamycin

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; HYDRALAZINE; IMIDAPRIL; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE INHIBITOR; RAPAMYCIN; S6 KINASE;

EID: 0033794721     PISSN: 09203206     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1007897308187     Document Type: Article
Times cited : (20)

References (50)
  • 4
    • 0024553336 scopus 로고
    • Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells
    • (1989) J Clin Invest , vol.83 , pp. 1774-1777
    • Uttam, C.G.1    Hassid, A.2
  • 7
    • 0030717697 scopus 로고    scopus 로고
    • Chronic angiotensin-converting enzyme inhibition and angiotensin II type 1 receptor blockade: Effects on cardiovascular remodeling in rats induced by the long-term blockade of nitric oxide synthesis
    • (1997) Hypertension , vol.30 , pp. 1621-1627
    • Takemoto, M.1    Egashira, K.2    Tomita, H.3
  • 8
    • 0028847159 scopus 로고
    • Rapamycin selectively inhibits angiotensin li-induced increase in protein synthesis in cardiac myocytes in vitro
    • (1995) Circ Res , vol.77 , pp. 1040-1052
    • Sadoshima, J.1    Izumo, S.2
  • 9
    • 0030807080 scopus 로고    scopus 로고
    • Rapamycin inhibits α1-adrenergic receptor-stimulated cardiac myocyte hypertrophy but not activation of hypertophy-associated genes. Evidence for involvement of p70 S6 kinase
    • (1997) Circ Res , vol.81 , pp. 176-186
    • Boluyt, M.O.1    Zheng, J.S.2    Younes, A.3
  • 10
    • 0019960870 scopus 로고
    • Alternations in vascular smooth muscle mass in the spontaneously hypertensive rat: Role of cellular hypertrophy, hyperploidy and hyperplasia
    • (1982) Circ Res , vol.51 , pp. 280-289
    • Owen, G.K.1    Schwartz, S.M.2
  • 15
    • 0028907314 scopus 로고
    • Role of p70 S6 protein kinase in angiotensin II-induced protein synthesis in vascular smooth muscle cells
    • (1995) J Biol Chem , vol.270 , pp. 5225-5231
    • Giasson, E.1    Meloche, S.2
  • 20
    • 0026343833 scopus 로고
    • Pharamcological studies on TA-6366, a new inhibitor: II. Effects of long-term administration from the prehypertensive stage on blood pressure, relative heart weight and ACE activity of various tissues in spontaneously hypertensive rats (SHRs)
    • (1991) Japan J Pharmacol , vol.57 , pp. 517-526
    • Kubo, M.1    Ochiai, T.2    Kato, J.3    Ishida, R.4
  • 22
    • 0001444358 scopus 로고    scopus 로고
    • Tacrolimus (FK506) and sirolimus (rapamycin) in combination are not antagonistic but produce extended graft survival in cardiac transplantation in the rat
    • (1997) Transplantation , vol.64 , pp. 1853-1856
    • Vu, M.D.1    Qi, S.2    Xu, D.3
  • 36
    • 0025291205 scopus 로고
    • Translational dynamics Interactions between the translational factors, tRNA and ribosomes during eukaryotic protein synthesis
    • (1990) Eur J Biochem , vol.191 , pp. 1-17
    • Nygard, O.1    Nilsson, L.2
  • 37
    • 0028908804 scopus 로고
    • Activation of pp70/85 S6 kinase in interleukin-2-responsive lymphoid cells is mediated by phophatidylinositol 3 kinase and inhibited by cyclic AMP
    • (1995) Mol Cell Biol , vol.15 , pp. 326-337
    • Monfar, M.1    Lemon, K.P.2    Gammer, T.C.3
  • 39
    • 0027983480 scopus 로고
    • Positive regulation of the cAMP-responsive activator CREM by the p70 S6 kinase: An alternative route to mitogen-induced gene expression
    • (1994) Cell , vol.79 , pp. 81-91
    • De Groot, R.P.1    Ballou, L.M.2    Sassone, C.P.3
  • 44
    • 0030658903 scopus 로고    scopus 로고
    • Bradykinin-mediated cardiovascular protective actions of ACE inhibitors: A new dimension in antiischaemic therapy?
    • (1997) Drugs , vol.54 , pp. 59-70
    • Remme, W.J.1
  • 46
  • 47
    • 0030449250 scopus 로고    scopus 로고
    • Protein kinase C, but not tyrosine kinases or Ras, plays a critical role in angiotensin II-induced activation of Raf-1 kinase and extracellular signal-regulated protein kinases in cardiac myocytes
    • (1996) J Biol Chem , vol.271 , pp. 33592-33597
    • Zou, Y.1    Komuro, I.2    Yamazaki, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.