Inhibition of nitric oxide synthesis increases adenosine production via an extracellular pathway through activation of Protein Kinase C

Circulation

Volumn 96, Issue 5, 1997, Pages 1586-1592

  Minamino, Tetsuo ^a   Kitakaze, Masafumi ^a   Node, Koichi ^a   Funaya, Hiroharu ^a   Hori, Masatsugu ^a  

^a OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

Adenosine; Cells; Nitric oxide; Proteins

Indexed keywords

ADENOSINE; ECTO 5' NUCLEOTIDASE; NITRIC OXIDE; PROTEIN KINASE C;

ANIMAL EXPERIMENT; ARTICLE; BLOOD VESSEL REACTIVITY; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; DOG; ENZYME ACTIVATION; HEART MUSCLE; HEART PACING; HUMAN; HUMAN CELL; HYPEREMIA; LEFT ANTERIOR DESCENDING CORONARY ARTERY; NONHUMAN; PRIORITY JOURNAL; VASODILATATION;

EID: 0030882548     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.96.5.1586     Document Type: Article

References (34)

1. Kelm M, Schrader J. Control of coronary vascular tone by nitric oxide. Circ Res. 1990;66:1561-1575.
2. Moncada S, Palmer RM, Higgs EA. Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol Rev. 1991;43:109-142.
3. Berne RM. The role of adenosine in the regulation of coronary blood flow. Circ Res. 1980;47:807-813.
4. Kitakaze M, Hori M, Kamada T. Interaction between adenosine and alpha-adrenoceptor activity and its role of ischemia and reperfusion. Cardiovasc Res. 1992;27:18-27.
5. Minamino T, Kitakaze M, Komamura K, Node K, Takeda H, Inoue M, Hori M, Kamada T. Activation of protein kinase C increases adenosine production in the hypoxic canine coronary artery through the extracellular pathway. Arterioscler Thromb Vase Biol. 1995;15:2298-2304.
6. Schulz R, Triggle CR. Role of NO in vascular smooth muscle and cardiac muscle function. Trends Pharmacol Sci. 1994;15:255-259.
7. Woolfson RG, Patel VC, Neild GH, Yellon DM. Inhibition of nitric oxide synthesis reduces infarct size by an adenosine-dependent mechanism. Circulation. 1995;91:1545-1551.
8. Kostic MM, Schrader J. Role of nitric oxide in reactive hyperemia of the guinea pig heart. Circ Res. 1992;70:208-212.
9. Matsunaga T, Okumura K, Tsunoda R, Tayama S, Tabuchi T, Yasue H. Role of adenosine in regulation of coronary flow in dogs with inhibited synthesis of endothelium-derived nitric oxide. Am J Phvsiol. 1996;270:H427-H434.
10. Siegfried G, Amiel C, Friedlander G. Inhibition of ecto-5′-nucleotidase by nitric oxide donors: implications in renal epithelial cells. J Biol Chem. 1996;271:4659-4664.
11. 1-Adrenoceptor activation increases ecto-5′-nucleotidase activity and adenosine release in rat cardiomyocytes by activating protein kinase C. Circulation. 1995;91:2226-2234.
12. Kitakaze M, Node K, Minamino T, Komamura K, Funaya H, Shinozaki Y, Chujo M, Mori H, Inoue M, Hori M, Kamada T. Role of activation of protein kinase C in the infarct size-limiting effect of ischemic preconditioning through activation of ecto-5′-nucleotidase. Circulation. 1996;93:781-791.
13. Gopalakrishna R, Chen ZH, Gundimeda U. Nitric oxide and nitric oxide-generating agents induce a reversible inactivation of protein kinase C activity and phorbol ester binding. J Biol Chem. 1993;268: 27180-27185.
14. Minamino T, Kitakaze M, Morioka T, Node K, Shinozaki Y, Chujo M, Mori H, Takeda H, Inoue M, Hori M, Kamada T. Bidirectional effects of aminophylline on myocardial ischemia. Circulation. 1995; 92:1254-1260.
15. Kitakaze M, Hori M, Morioka T, Minamino T, Takashima S, Sato H, Shinozaki Y, Chujo M, Mori H, Inoue M, Kamada T. Infarct size-limiting effect of ischemic preconditioning is blunted by inhibition of 5′-nucleotidase activity and attenuation of adenosine release. Circulation. 1994;89:1237-1246.
16. Toullec D, Pianetti P, Coste H, Bellevergue P, Grand-Perret T, Ajakane B, Baudet V, Boissin P, Boursier E, Loriolle F, Duhamel L, Charon D, Kirilovsky J. The bisindolylmaleimide GF109203X is a potent and selective inhibitor of protein kinase C. J Biol Chem. 1991;266:15771-15781.
17. Kobaysahi E, Nakano H, Morimoto M, Tamaoki T. Calphostin C (UCN-1028C), a novel microbial compound, is a highly potent and specific inhibitor of protein kinase C. Biochem Biophys Res Commun. 1989;159:548-553.
18. Hohorst HJ. Tissue lactate analysis. In: Bergmeyer H, ed. Methods of Enzymatic Analysis. New York, NY: Academic Press; 1963: 266-270.
19. Minamino T, Kitakaze M, Morioka T, Node K, Komamura K, Takeda H, Inoue M, Hori M, Kamada T. Cardioprotection due to preconditioning correlates with increased ecto-5′-nucleotidase activity. Am J Physiol. 1996;270:H238-H244.
20. Smith K, Varon HH, Race GJ, Paulson DL, Urshel HC, Mallams JT. Serum 5′-nucleotidase in patients with tumor in the liver. Cancer. 1965;19:1281-1285.
21. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with Folin phenol reagent. J Biol Chem. 1951;193: 265-275.
22. Kato J, Lanier-Smith KL, Currie MG. Cyclic GMP down-regulates atrial natriuretic peptide receptors on cultured vascular endothelial cells. J Biol Chem. 1992;266:14681-14685.
23. Jones CJH, Kuo L, Davis MJ, Defily DV, Chilian WM. Role of nitric oxide in the coronary microvascular responses to adenosine and increased metabolic demand. Circulation. 1995;91: 1807-1813.
24. Puyhasset L, Bea ML, Ghaleh B, Giudicelli JF, Berdeaux A. Coronary and systemic hemodynamic effects of sustained inhibition of nitric oxide synthesis in conscious dogs: evidence for cross talk between nitric oxide and cyclooxygenase in coronary vessels. Circ Res. 1996;79:343-357.
25. Parent R, Pare R, Lavallee M. Contribution of nitric oxide to dilation of resistance coronary vessels in conscious dogs. Am J Physiol. 1992;262:H10-H16.
26. Luscher TF, Vanhoutte PM. The endothelium: modulator of cardiovascular function. Boca Raton, Fla: CRC Press; 1990.
27. Pearson PJ, Vanhoutte PM. Vasodilator and vasoconstrictor substances produced by the endothelium. Rev Physiol Biochem Pharmacol 1993;122:1-67.
28. Bodin P, Basiley D, Burnstock G. Increased flow-induced ATP release from isolated vascular endothelial cells but not smooth cells. Br J Pharmacol. 1991;103:1203-1205.
29. Low MG, Finean JB. Specific release of plasma membrane enzymes by a phosphatidylinositol-specific phospholipase C. Biochim Biophys Acta. 1978;508:565-570.
30. Kitakaze M, Mori H, Sakamoto H, Inoue M. Disappearance of infarct size-limiting effect is attributable to dephosphorylation process of ecto-5′-nucleotidase. Circulation. 1995;92(suppl I):I-524. Abstract.
31. Stamler JS. Redox signaling: nitrosylation and related target interactions of nitric oxide. Cell. 1994;8:931-936.
32. Murohara T, Parkinson SJ, Waldman SA, Lefer AM. Inhibition of nitric oxide biosynthesis promotes P-selectin expression in platelets: role of protein kinase C. Arterioscler Thromb Vase Biol. 1995;15: 2068-2075.
33. Quyyumi A, Dakak N, Andrews NP, Gilligan DM, Panza JA, Canon RO. Contribution of nitric oxide to metabolic coronary vasodilation in the human heart. Circulation. 1995;92:320-326.
34. Forstermann U, Mugge A, Alheid U, Haverich A, Frolich JC. Selective attenuation of endothelium-mediated vasodilation in atherosclerotic human coronary arteries. Circ Res. 1988;62: 185-190.