Cloning and identification of regulatory gene UL76 of human cytomegalovirus

Journal of General Virology

Volumn 81, Issue 10, 2000, Pages 2407-2416

  Wang, S K ^a   Duh, C Y ^a   Chang, T T ^a  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; GREEN FLUORESCENT PROTEIN; HISTIDINE; HYBRID PROTEIN; POLYCLONAL ANTIBODY; REGULATOR PROTEIN;

ARTICLE; CELL CYCLE; CELL NUCLEUS; CONTROLLED STUDY; CYTOMEGALOVIRUS INFECTION; ENHANCER REGION; GENE CONSTRUCT; GENE EXPRESSION; GENE FUNCTION; GENE INSERTION; GENE LIBRARY; GENE LOCUS; GENETIC ANALYSIS; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN CYTOMEGALOVIRUS; IMMEDIATE EARLY GENE; IMMUNOREACTIVITY; IN VITRO STUDY; MOLECULAR CLONING; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PRIORITY JOURNAL; PROKARYOTE; PROMOTER REGION; PROTEIN LOCALIZATION; REGULATOR GENE; VIRUS GENOME;

CYTOMEGALOVIRUS; DNA VIRUSES; HUMAN HERPESVIRUS 5; PROKARYOTA;

EID: 0033790781     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/0022-1317-81-10-2407     Document Type: Article

References (43)

1. Metal-affinity separations: A new dimension in protein processing
2. Proteins associated with purified human cytomegalovirus particles
3. An isoform variant of the cytomegalovirus immediate-early autorepressor functions as a transcriptional activator
4. A novel herpes simplex virus gene (UL49A) encodes a putative membrane protein with counterparts in other herpesviruses
5. Cytomegalovirus
6. The enhanceosome and transcriptional synergy
7. Human cytomegalovirus clinical isolates carry at least 19 genes not found in laboratory strains
8. Analysis of the protein-coding content of the sequence of human cytomegalovirus strain AD169
9. Identification and expression of a human cytomegalovirus glycoprotein with homology to the Epstein-Barr virus BXLF2 product, varicella-zoster virus gpIII, and herpes simplex virus type 1 glycoprotein H
10. The BamHI fragment 9 of pseudorabies virus contains gene homologous to the UL24, UL25, UL26, and UL26.5 genes of herpes simplex virus type 1
11. The UL84 protein of human cytomegalovirus acts as a transdominant inhibitor of immediate-early-mediated transactivation that is able to prevent viral replication
12. Structure and assembly of the virion
13. Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells
14. A human cytomegalovirus early promoter with upstream negative and positive cisacting elements: IE2 negates the effect of the negative element, and NF-Υ binds to the positive element
15. The human cytomegalovirus UL74 gene encodes the third component of the glycoprotein H-glycoprotein Lcontaining envelope complex
16. Intracellular formation and processing of the heterotrimeric gH-gL-gO (gCIII) glycoprotein envelope complex of human cytomegalovirus
17. A conserved open reading frame that overlaps the herpes simplex virus thymidine kinase gene is important for viral growth in cell culture
18. Importance of the herpes simplex virus UL24 gene for productive ganglionic infection in mice
19. Human cytomegalovirus late protein encoded by ie2: A trans-activator as well as a repressor of gene expression
20. A short amino acid sequence able to specify nuclear location
21. Glycoprotein H of human cytomegalovirus (HCMV) forms a stable complex with the HCMV UL115 gene product
22. Repression and activation by multiprotein complexes that alter chromatin structure
23. The 86-kilodalton IE-2 protein of human cytomegalovirus is a sequence-specific DNA-binding protein that interacts directly with the negative autoregulatory response element located near the cap site of the IE-1/2 enhancer-promoter
24. Human cytomegalovirus contains a tegument protein that enhances transcription from promoters with upstream ATF and AP-1 cis-acting elements
25. An in vitro system for human cytomegalovirus immediate early 2 protein (IE2)-mediated site-dependent repression of transcription and direct binding of IE2 to the major immediate early promoter
26. Regulation of human cytomegalovirus immediate-early gene expression
27. Characterization of a conserved gene block in the murine cytomegalovirus genome
28. Cytomegaloviruses and their replication
29. Eleven loci encoding trans-acting factors are required for transient complementation of human cytomegalovirus oriLyt-dependent DNA replication
30. Identification of the herpes simplex virus type 1 gene encoding the dUTPase
31. Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: Identification of a class of bipartite nuclear targeting sequence
32. Herpes simplex viruses and their replication
33. Thymidine kinase deletion mutants of herpes simplex virus type 1
34. A simple phase-extraction assay for chloramphenicol acyltransferase activity
35. Latent and persistent infections of monocytes and macrophages
36. Human cytomegalovirus UL102 gene
37. The human cytomegalovirus major immediate-early gene
38. Phenotypic and genotypic characterization of locus Syn 5 in herpes simplex virus 1
39. A specific subform of the human cytomegalovirus transactivator protein pUL69 is contained within the tegument of virus particles
40. UL69 of human cytomegalovirus, an open reading frame with homology to ICP27 of herpes simplex virus, encodes a transactivator of gene expression
41. Optimized codon usage and chromophore mutations provide enhanced sensitivity with the green fluorescent protein
42. Mapping a putative pyruvoyl decarboxylase active site to human cytomegalovirus open reading frame UL77