-
1
-
-
0027517590
-
Effects of thrombin and thrombin receptor activating peptides on rat aortic vascular smooth muscle
-
Antonaccio M.J., Normandin D., Serafino R., Moreland S. Effects of thrombin and thrombin receptor activating peptides on rat aortic vascular smooth muscle. J Pharmacol Exp Ther. 266:1993;125-132.
-
(1993)
J Pharmacol Exp Ther
, vol.266
, pp. 125-132
-
-
Antonaccio, M.J.1
Normandin, D.2
Serafino, R.3
Moreland, S.4
-
2
-
-
0031730635
-
Thrombomodulin: An overview and potential implications in vascular disorders
-
Boffa M.C., Karmochkine M. Thrombomodulin an overview and potential implications in vascular disorders . Lupus. 7:1998;S120-S125.
-
(1998)
Lupus
, vol.7
, pp. 120-S125
-
-
Boffa, M.C.1
Karmochkine, M.2
-
3
-
-
0030950165
-
Anticoagulant properties of the vascular endothelium
-
Bombeli T., Mueller M., Haeberli A. Anticoagulant properties of the vascular endothelium. Thromb Haemost. 77:1997;408-423.
-
(1997)
Thromb Haemost
, vol.77
, pp. 408-423
-
-
Bombeli, T.1
Mueller, M.2
Haeberli, A.3
-
4
-
-
0026582531
-
Synergism between the contractile effect of epidermal growth factor and that of des-Arg9-bradykinin or of α-thrombin in rabbit aortic rings
-
de Blois D., Drapeau G., Petitclerc E., Marceau F. Synergism between the contractile effect of epidermal growth factor and that of des-Arg9-bradykinin or of α-thrombin in rabbit aortic rings. Br J Pharmacol. 105:1992;959-967.
-
(1992)
Br J Pharmacol
, vol.105
, pp. 959-967
-
-
De Blois, D.1
Drapeau, G.2
Petitclerc, E.3
Marceau, F.4
-
5
-
-
0033014958
-
Proteinase-activated receptors: A growing family of heptahelical receptors for thrombin, trypsin and tryptase
-
Dery O., Bunnett N.W. Proteinase-activated receptors a growing family of heptahelical receptors for thrombin, trypsin and tryptase . Biochem Soc Trans. 27:1999;246-254.
-
(1999)
Biochem Soc Trans
, vol.27
, pp. 246-254
-
-
Dery, O.1
Bunnett, N.W.2
-
6
-
-
0025264573
-
In vivo behavior of detergent-solubilized purified rabbit thrombomodulin on intravenous injection into rabbits
-
Ehrlich H.J., Esmon N.L., Bang N.U. In vivo behavior of detergent-solubilized purified rabbit thrombomodulin on intravenous injection into rabbits. J Lab Clin Med. 115:1990;182-189.
-
(1990)
J Lab Clin Med
, vol.115
, pp. 182-189
-
-
Ehrlich, H.J.1
Esmon, N.L.2
Bang, N.U.3
-
7
-
-
0032845209
-
Regulation and functions of the protein C anticoagulant pathway
-
Esmon C.T., Gu J.M., Xu J., Qu D., Stearns-Kurosawa D.J., Kurosawa S. Regulation and functions of the protein C anticoagulant pathway. Haematologica. 84:1999;363-368.
-
(1999)
Haematologica
, vol.84
, pp. 363-368
-
-
Esmon, C.T.1
Gu, J.M.2
Xu, J.3
Qu, D.4
Stearns-Kurosawa, D.J.5
Kurosawa, S.6
-
8
-
-
0030970663
-
Activated protein C resistance, factor V Leiden and peripheral vascular disease
-
Foley P.W., Irvine C.D., Standen G.R., Morse C., Smith F.T., McGrath C., Baird R.N., Lamont P.M. Activated protein C resistance, factor V Leiden and peripheral vascular disease. Cardiovas Surg. 5:1997;157-160.
-
(1997)
Cardiovas Surg
, vol.5
, pp. 157-160
-
-
Foley, P.W.1
Irvine, C.D.2
Standen, G.R.3
Morse, C.4
Smith, F.T.5
McGrath, C.6
Baird, R.N.7
Lamont, P.M.8
-
9
-
-
0032250114
-
Circulating thrombomodulin and hematological alterations in type 2 diabetic patients with retinopathy
-
Fujiwara Y., Tagami S., Kawakami Y. Circulating thrombomodulin and hematological alterations in type 2 diabetic patients with retinopathy. J Atherosc Thromb. 5:1998;21-28.
-
(1998)
J Atherosc Thromb
, vol.5
, pp. 21-28
-
-
Fujiwara, Y.1
Tagami, S.2
Kawakami, Y.3
-
10
-
-
0027943163
-
Identification, cloning, and regulation of a novel endothelial cell protein C/activated protein C receptor
-
Fukudome K., Esmon C.T. Identification, cloning, and regulation of a novel endothelial cell protein C/activated protein C receptor. J Biol Chem. 269:1994;26486-26491.
-
(1994)
J Biol Chem
, vol.269
, pp. 26486-26491
-
-
Fukudome, K.1
Esmon, C.T.2
-
11
-
-
0030016347
-
The endothelial cell protein C receptor. Cell surface expression and direct ligand binding by the soluble receptor
-
Fukudome K., Kurosawa S., Stearns-Kurosawa D.J., He X., Rezaie A.R., Esmon C.T. The endothelial cell protein C receptor. Cell surface expression and direct ligand binding by the soluble receptor. J Biol Chem. 271:1996;17491-17498.
-
(1996)
J Biol Chem
, vol.271
, pp. 17491-17498
-
-
Fukudome, K.1
Kurosawa, S.2
Stearns-Kurosawa, D.J.3
He, X.4
Rezaie, A.R.5
Esmon, C.T.6
-
12
-
-
0032489916
-
Activation mechanism of anticoagulant protein C in large blood vessels involving the endothelial cell protein C receptor
-
Fukudome K., Ye X., Tsuneyoshi N., Tokunaga O., Sugawara K., Mizokami H., Kimoto M. Activation mechanism of anticoagulant protein C in large blood vessels involving the endothelial cell protein C receptor. J Exp Med. 187:1998;1029-1035.
-
(1998)
J Exp Med
, vol.187
, pp. 1029-1035
-
-
Fukudome, K.1
Ye, X.2
Tsuneyoshi, N.3
Tokunaga, O.4
Sugawara, K.5
Mizokami, H.6
Kimoto, M.7
-
13
-
-
0028293716
-
Aminopeptidase modulation of the pharmacological responses to synthetic thrombin receptor agonists
-
Godin D., Marceau F., Beaule C., Rioux F., Drapeau G. Aminopeptidase modulation of the pharmacological responses to synthetic thrombin receptor agonists. Eur J Pharmacol. 253:1994;225-230.
-
(1994)
Eur J Pharmacol
, vol.253
, pp. 225-230
-
-
Godin, D.1
Marceau, F.2
Beaule, C.3
Rioux, F.4
Drapeau, G.5
-
15
-
-
0025218438
-
Antithrombotic effect of recombinant human thrombomodulin on thrombin-induced thromboembolism in mice
-
Gomi K., Zushi M., Honda G., Kawahara S., Matsuzaki O., Kanabayashi T., Yamamoto S., Maruyama I., Suzuki K. Antithrombotic effect of recombinant human thrombomodulin on thrombin-induced thromboembolism in mice. Blood. 75:1990;1396-1399.
-
(1990)
Blood
, vol.75
, pp. 1396-1399
-
-
Gomi, K.1
Zushi, M.2
Honda, G.3
Kawahara, S.4
Matsuzaki, O.5
Kanabayashi, T.6
Yamamoto, S.7
Maruyama, I.8
Suzuki, K.9
-
16
-
-
15144361590
-
Novel antithrombotics based on modulation of the protein C pathway
-
Grinnell B.W., Yan S.B. Novel antithrombotics based on modulation of the protein C pathway. Coronary Artery Dis. 9:1998;89-97.
-
(1998)
Coronary Artery Dis
, vol.9
, pp. 89-97
-
-
Grinnell, B.W.1
Yan, S.B.2
-
17
-
-
0029939761
-
Surface thrombomodulin modulates thrombin receptor responses on vascular smooth muscle cells
-
Grinnell B.W., Berg D.T. Surface thrombomodulin modulates thrombin receptor responses on vascular smooth muscle cells. Am J Physiol. 270:1996;H603-H609.
-
(1996)
Am J Physiol
, vol.270
, pp. 603-H609
-
-
Grinnell, B.W.1
Berg, D.T.2
-
18
-
-
0026630953
-
Direct detection of activated protein C in blood from human subjects
-
Gruber A., Griffin J.H. Direct detection of activated protein C in blood from human subjects. Blood. 77:1992;2340-2348.
-
(1992)
Blood
, vol.77
, pp. 2340-2348
-
-
Gruber, A.1
Griffin, J.H.2
-
19
-
-
0027444776
-
Generation of activated protein C during thrombolysis
-
Gruber A., Pal A., Kiss R.G., Sas G., Griffin J.H. Generation of activated protein C during thrombolysis. Lancet. 342:1993;1275-1276.
-
(1993)
Lancet
, vol.342
, pp. 1275-1276
-
-
Gruber, A.1
Pal, A.2
Kiss, R.G.3
Sas, G.4
Griffin, J.H.5
-
20
-
-
0030097490
-
Evaluation of activated protein C on canine infarct size in a nonthrombotic model of myocardial reperfusion injury
-
Hahn R.A., MacDonald B.R., Chastain M., Grinnell B.W., Simpson P.J. Evaluation of activated protein C on canine infarct size in a nonthrombotic model of myocardial reperfusion injury. J Pharmacol Exp Ther. 276:1996;1104-1110.
-
(1996)
J Pharmacol Exp Ther
, vol.276
, pp. 1104-1110
-
-
Hahn, R.A.1
MacDonald, B.R.2
Chastain, M.3
Grinnell, B.W.4
Simpson, P.J.5
-
21
-
-
0027435111
-
Antithrombotic effects of thromin-induced activation of endogenous protein C
-
Hansen S.R., Griffin J.H., Harker L.A., Kelley A.B., Esmon C.T., Gruber A. Antithrombotic effects of thromin-induced activation of endogenous protein C. J Clin Invest. 92:1993;2003-2012.
-
(1993)
J Clin Invest
, vol.92
, pp. 2003-2012
-
-
Hansen, S.R.1
Griffin, J.H.2
Harker, L.A.3
Kelley, A.B.4
Esmon, C.T.5
Gruber, A.6
-
22
-
-
0033506048
-
Proteinase-activated receptor 4 (PAR(4)): Action of PAR(4)-activating peptides in vascular and gastric tissue and lack of cross-reactivity with PAR(1) and PAR(2)
-
Hollenberg M.D., Saifeddine M., AlAni B., Gui Y. Proteinase-activated receptor 4 (PAR(4)) action of PAR(4)-activating peptides in vascular and gastric tissue and lack of cross-reactivity with PAR(1) and PAR(2) . Can J Physiol Pharmacol. 77:1999;458-464.
-
(1999)
Can J Physiol Pharmacol
, vol.77
, pp. 458-464
-
-
Hollenberg, M.D.1
Saifeddine, M.2
Alani, B.3
Gui, Y.4
-
23
-
-
4243240386
-
Activated protein C induction of MCP-1 in human umbilical vein endothelial cells: A possible role for endothelial cell nitric oxide synthase
-
Hooper WC, Phillips DJ, Evant BL, Renshaw M. Activated protein C induction of MCP-1 in human umbilical vein endothelial cells: a possible role for endothelial cell nitric oxide synthase. Blood 90 (Supplement 1) p. 301a, 1997.
-
(1997)
Blood
, vol.90
, Issue.1 SUPPL.
-
-
Hooper, W.C.1
Phillips, D.J.2
Evant, B.L.3
Renshaw, M.4
-
24
-
-
0031266015
-
Antithrombin III supplementation in severe sepsis: Beneficial effects on organ dysfunction
-
Inthron D., Hoffmann J.N., Hartl W.H., Muhlbayer D., Jochum M. Antithrombin III supplementation in severe sepsis beneficial effects on organ dysfunction . Shock. 8:1997;328-334.
-
(1997)
Shock
, vol.8
, pp. 328-334
-
-
Inthron, D.1
Hoffmann, J.N.2
Hartl, W.H.3
Muhlbayer, D.4
Jochum, M.5
-
25
-
-
0032514474
-
A dual thrombin receptor system for platelet activation
-
Kahn M.L., Zheng Y.W., Huang W., Bigornia V., Zeng D., Moff S., Farese R.V. Jr, Tam C., Coughlin S.R. A dual thrombin receptor system for platelet activation. Nature. 394:1998;690-694.
-
(1998)
Nature
, vol.394
, pp. 690-694
-
-
Kahn, M.L.1
Zheng, Y.W.2
Huang, W.3
Bigornia, V.4
Zeng, D.5
Moff, S.6
Farese R.V., Jr.7
Tam, C.8
Coughlin, S.R.9
-
26
-
-
0031045748
-
Plasma levels of protein C, protein S, and antithrombin III in patients with subarachnoid haemorrhage
-
Kanamaru K., Waga S., Tanaka K. Plasma levels of protein C, protein S, and antithrombin III in patients with subarachnoid haemorrhage. Acta Neurochir. 139:1997;134-140.
-
(1997)
Acta Neurochir
, vol.139
, pp. 134-140
-
-
Kanamaru, K.1
Waga, S.2
Tanaka, K.3
-
27
-
-
0033537469
-
Poor response to activated protein C as a prominent risk predictor of advanced atherosclerosis and arterial disease
-
Kiechl S., Muigg A., Santer P., Mitterer M., Egger G., Oberhollenzer M., Oberhollenzer F., Mayr A., Gasperi A., Poewe W., Willeit J. Poor response to activated protein C as a prominent risk predictor of advanced atherosclerosis and arterial disease. Circulation. 99:1999;614-619.
-
(1999)
Circulation
, vol.99
, pp. 614-619
-
-
Kiechl, S.1
Muigg, A.2
Santer, P.3
Mitterer, M.4
Egger, G.5
Oberhollenzer, M.6
Oberhollenzer, F.7
Mayr, A.8
Gasperi, A.9
Poewe, W.10
Willeit, J.11
-
28
-
-
8044259613
-
The involvement of a novel mechanism distinct from the thrombin receptor in the vasocontraction induced by trypsin
-
Komuro T., Miwa S., Minowa T., Okamoto Y., Enoki T., Ninomiya H., Zhang X.F., Uemura Y., Kikuchi H., Masaki T. The involvement of a novel mechanism distinct from the thrombin receptor in the vasocontraction induced by trypsin. Br J Pharmacol. 120:1997;851-856.
-
(1997)
Br J Pharmacol
, vol.120
, pp. 851-856
-
-
Komuro, T.1
Miwa, S.2
Minowa, T.3
Okamoto, Y.4
Enoki, T.5
Ninomiya, H.6
Zhang, X.F.7
Uemura, Y.8
Kikuchi, H.9
Masaki, T.10
-
29
-
-
0030776168
-
Human protein C receptor is present primarily on endothelium of large blood vessels: Implications for the control of the protein C pathway
-
Laszik Z., Mitro A., Taylor F.B. Jr, Ferrell G., Esmon C.T. Human protein C receptor is present primarily on endothelium of large blood vessels implications for the control of the protein C pathway . Circulation. 96:1997;3633-3640.
-
(1997)
Circulation
, vol.96
, pp. 3633-3640
-
-
Laszik, Z.1
Mitro, A.2
Taylor F.B., Jr.3
Ferrell, G.4
Esmon, C.T.5
-
31
-
-
0031731278
-
Biology of endothelium
-
Maruyama I. Biology of endothelium. Lupus. 7:(suppl. 2):1998;S41-S43.
-
(1998)
Lupus
, vol.7
, Issue.SUPPL. 2
, pp. 41-S43
-
-
Maruyama, I.1
-
32
-
-
0031544005
-
Thrombomodulin levels in patients with coronary artery disease
-
Mihara H., Murai A., Handa K., Saku K., Shirai K., Tanaka K., Arakawa K. Thrombomodulin levels in patients with coronary artery disease. Artery. 22:1997;293-308.
-
(1997)
Artery
, vol.22
, pp. 293-308
-
-
Mihara, H.1
Murai, A.2
Handa, K.3
Saku, K.4
Shirai, K.5
Tanaka, K.6
Arakawa, K.7
-
34
-
-
0031951276
-
Pharmacokinetics and safety of a novel recombinant soluble human thrombomodulin, ART-123, in healthy male volunteers
-
Nakashima M., Kanamaru M., Umemura K., Tsuruta K. Pharmacokinetics and safety of a novel recombinant soluble human thrombomodulin, ART-123, in healthy male volunteers. J Clin Pharmacol. 38:1998;40-44.
-
(1998)
J Clin Pharmacol
, vol.38
, pp. 40-44
-
-
Nakashima, M.1
Kanamaru, M.2
Umemura, K.3
Tsuruta, K.4
-
35
-
-
0021738766
-
Mechanisms of adenosine triphosphate-, thrombin-, and trypsin-induced relaxation of rat thoracic aorta
-
Rapoport R.M., Draznin M.B., Murad F. Mechanisms of adenosine triphosphate-, thrombin-, and trypsin-induced relaxation of rat thoracic aorta. Circ Res. 55:1984;468-479.
-
(1984)
Circ Res
, vol.55
, pp. 468-479
-
-
Rapoport, R.M.1
Draznin, M.B.2
Murad, F.3
-
36
-
-
0030843884
-
Thrombomodulin structure and function
-
Sadler J.E. Thrombomodulin structure and function. Thromb Haemost. 78:1997;392-395.
-
(1997)
Thromb Haemost
, vol.78
, pp. 392-395
-
-
Sadler, J.E.1
-
37
-
-
0025952193
-
Inhibitory effect of the endothelium on thrombin-induced contraction in rabbit aorta
-
Sakiyama N., Wakabayashi I., Hatake K., Kakishita E. Inhibitory effect of the endothelium on thrombin-induced contraction in rabbit aorta. Gen Pharmacol. 22:1991;1005-1009.
-
(1991)
Gen Pharmacol
, vol.22
, pp. 1005-1009
-
-
Sakiyama, N.1
Wakabayashi, I.2
Hatake, K.3
Kakishita, E.4
-
38
-
-
0031757736
-
Activated protein C resistance in patients with peripheral vascular disease
-
Sampram E.S., Lindblad B., Dahlback B. Activated protein C resistance in patients with peripheral vascular disease. J Vasc Surg. 28:1998;624-629.
-
(1998)
J Vasc Surg
, vol.28
, pp. 624-629
-
-
Sampram, E.S.1
Lindblad, B.2
Dahlback, B.3
-
39
-
-
0023909346
-
Pharmacodynamic effects of tosyl-arginine methyp ester (TAME) on isolated human arteries
-
White R.P. Pharmacodynamic effects of tosyl-arginine methyp ester (TAME) on isolated human arteries. Gen Pharmacol. 19:1988;387-392.
-
(1988)
Gen Pharmacol
, vol.19
, pp. 387-392
-
-
White, R.P.1
-
40
-
-
0023201281
-
Pharmacodynamic evaluation of human cerebral arteries in the genesis of vasospasm
-
White R.P., Robertson J.T. Pharmacodynamic evaluation of human cerebral arteries in the genesis of vasospasm. Neurosurgery. 21:1987;523-531.
-
(1987)
Neurosurgery
, vol.21
, pp. 523-531
-
-
White, R.P.1
Robertson, J.T.2
-
41
-
-
0021911809
-
Role of plasmin, thrombin and antithrombin III as etiological factors in delayed vasospasm
-
White R.P., Robertson J.T. Role of plasmin, thrombin and antithrombin III as etiological factors in delayed vasospasm. Neurosurgery. 16:1985;27-35.
-
(1985)
Neurosurgery
, vol.16
, pp. 27-35
-
-
White, R.P.1
Robertson, J.T.2
-
42
-
-
0342696546
-
Endothelial cell protein C receptor (EPCR) constitutively translocates into the nucleus and also mediates activated protein C, but not protein C nuclear translocation
-
Washington, DC, Ed:PM Mannucci; 206
-
Xu J, Esmon CT. Endothelial cell protein C receptor (EPCR) constitutively translocates into the nucleus and also mediates activated protein C, but not protein C nuclear translocation. In: XVII Congress of the International Society on Thrombosis and Haemostasis. Washington, DC, 1999. Ed:PM Mannucci; 206.
-
(1999)
In: XVII Congress of the International Society on Thrombosis and Haemostasis
-
-
Xu, J.1
Esmon, C.T.2
-
43
-
-
0024343069
-
Antithrombin III stimulates prostacyclin production by cultured aortic endothelial cells
-
Yamauchi T., Umeda F., Inoguchi T., Nawata H. Antithrombin III stimulates prostacyclin production by cultured aortic endothelial cells. Biochem Biophys Res Commun. 163:1989;1404-1411.
-
(1989)
Biochem Biophys Res Commun
, vol.163
, pp. 1404-1411
-
-
Yamauchi, T.1
Umeda, F.2
Inoguchi, T.3
Nawata, H.4
-
44
-
-
0025053103
-
Characterization and novel purification of recombinant human protein C from three mammalian cell lines
-
Yan S.B., Razzano P., Chao Y.B., Walls J.D., Berg D.T., McClure D.B., Grinnell B.W. Characterization and novel purification of recombinant human protein C from three mammalian cell lines. Bio/Technology. 8:1990;655-661.
-
(1990)
Bio/Technology
, vol.8
, pp. 655-661
-
-
Yan, S.B.1
Razzano, P.2
Chao, Y.B.3
Walls, J.D.4
Berg, D.T.5
McClure, D.B.6
Grinnell, B.W.7
-
45
-
-
0026656071
-
Actions of thrombin and thrombin receptor peptide analogues in gastric and aortic smooth muscle: Development of bioassays for structure-activity studies
-
Yang S.G., Laniyonu A., Saifeddine M., Moore G.J., Hollenberg M.D. Actions of thrombin and thrombin receptor peptide analogues in gastric and aortic smooth muscle development of bioassays for structure-activity studies . Life Sci. 51:1992;1325-1332.
-
(1992)
Life Sci
, vol.51
, pp. 1325-1332
-
-
Yang, S.G.1
Laniyonu, A.2
Saifeddine, M.3
Moore, G.J.4
Hollenberg, M.D.5
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