Modulation of transferrin synthesis, transferrin receptor expression, iNOS expression and NO production in mouse macrophages by cytokines, either alone or in combination

Anticancer Research

Volumn 20, Issue 5, 2000, Pages 3331-3338

  Ryu, S Y ^a   Jeong, K S ^a   Kang, B N ^a   Park, S J ^a   Yoon, W K ^a   Kim, S H ^a   Kim, T H ^a  

^a Chungnam National University   (South Korea)

Author keywords

Cytokine; iNOS and NO; Transferrin; Transferrin receptor

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 1; INTERLEUKIN 6; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; TRANSFERRIN; TRANSFERRIN RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME SYNTHESIS; IMMUNOMODULATION; IRON KINETICS; IRON TRANSPORT; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION; INTERFERON TYPE II; INTERLEUKIN-1; INTERLEUKIN-6; MACROPHAGES, PERITONEAL; MICE; MICE, INBRED C3H; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; RECEPTORS, TRANSFERRIN; RNA, MESSENGER; TRANSFERRIN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0033789201     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. Iron withholding: A defense against infection and neoplasia
2. Lactoferrin uptake by mononuclear phagocytes
3. Effect of transferrin, lactoferrin and chelated iron on human T-lymphocytes
4. Linkage of cell-mediated immunity to iron metabolism
5. The biology of transferrin
6. Transferrin gene expression in the mammary gland of the rat. The enhancing effect of 17-oestradiol on the level of RNA is tissue-specific
7. Metal ion transporters in mammals: Structure, function and pathological implications
8. Effects of transferrin on the modulation of cytokine production on mouse spleen cells
9. Converse modulation of IRP1 and IRP2 by immunological stimuli in murine RAW 264.7 macrophages
10. Control of transferrin receptor expression via nitric oxide-mediated modulation of iron-regulatory protein 2
11. Nitric oxide-mediated induction of ferritin synthesis in J744 macrophages by inflammatory cytokines: Role of selective iron regulatory protein-2 down-regulation
12. Pathways for regulation of macrophage iron metabolism by the anti-inflammatory cytokines IL-4 and IL-13
13. The characterization of four monoclonal antibodies specific for mouse IL-5 and development of mouse and human IL-5 enzyme-linked immunosorbent
14. Cleavage of structural proteins during the assembly of the head of bacteriophages T4
15. Transferrin receptors synthesis is an early event in B cell activation
16. The transferrin receptor
17. Vascular smooth muscle-derived relaxing factor (MDRF) and its close similarity to nitric oxide
18. Biology of multifunctional cytokines: IL 6 and related molecules (IL-1 and TNF)
19. Regulation of transferrin receptor expression and ferritin contents in human mononuclear phagocytes. Coordinate up-regulation by iron transferrin and down-regulation by interferon gamma
20. LPS inhibits the intracellular growth of Legionella pneumophilia in thioglycolate elicited murine peritoneal macrophages by iron-dependent, tryptophan-independent, oxygen-independent, and arginine-independent mechanism
21. Effects of TNF-alpha and IL-1beta on iron metabolism by A549 cells and influence on cytotoxicity
22. Function and regulation of transferrin and ferritin
23. Transferrin and its receptors: Their roles in cell function
24. Mechanism of iron uptake by mammalian cells
25. Transferrin synthesis by macrophages: Up-regulation by γ-interferon and effect on lymphocyte proliferation
26. Cytokine-mediated regulation of transferrin synthesis in mouse macrophages and human T lymphocytes
27. Chaper 11. Cytokines
28. Expression and up-regulation of transferrin receptors and iron uptake in the epiplexus cells of different aged rats injected with lipopolysaccharide and interferon-gamma
29. Modulation of iron metabolism in monocyte cell line U937 by inflammatory cytokines: Changes in transferrin uptake, iron handling and ferritin mRNA
30. Nitric oxide induces apoptosis in mouse thymocytes
31. Blockade of nitric oxide formation down-regulates cyclooxygenase-2 and decreases PGE2 biosynthesis in macrophages
32. Up-regulation of nitric oxide production by interferon-gamma in cultured peritoneal macrophages from patients with cirrhosis
33. A nitric oxide production bioassay for interferon-gamma
34. Potential role of the JNK/SAPK signal transduction pathway in the induction of iNOS by TNF-alpha
35. Evaluation of the role of mitogen-activated protein kinases in the expression of inducible nitric oxide synthase by IFN-gamma and TNF-alpha in mouse macrophages
36. Differential induction of nitric oxide synthase in various organs of the mouse during endotoxaemia: Role of TNF-alpha and IL-1-beta
37. TNF-alpha enhances cardiac myocytes NO production through MAP kinase-mediated NF-kappaB activation
38. Nitric oxide signaling to iron-regulatory protein: Direct control of ferritin mRNA translation and transferrin receptor mRNA stability in transfected fibroblasts
39. The role of the transferrin receptor for the activation of human lymphocytes
40. γ-Interferon modulates human monocyte/macrophage transferrin receptor expression
41. Post-transcriptional regulation of transferrin receptor mRNA by IFN
42. Expression of the transferrin receptor on murine peritoneal macrophages is modulated by in vitro treatment with interferon gamma
43. Gamma-interferon up-regulates transferrin receptors and decreases membrane microviscosity in K562 cells
44. Iron regulations nitric oxide synthase activity by controlling nuclear transcription