Taxol reduces cytosolic E-cadherin and β-catenin levels in nasopharyngeal carcinoma cell line TW-039: Cross-talk between the microtubule- and actin-based cytoskeletons

Journal of Cellular Biochemistry

Volumn 79, Issue 4, 2000, Pages 542-556

  Lou, Pei Jen ^a,b   Chen, Wen Pin ^a   Lin, Chin Tarng ^a   Chen, Hui Chin ^b   Wu, Jiahn Chun ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Actin; Catenin; E cadherin; Microtubule; Nasopharyngeal carcinoma; Taxol

Indexed keywords

ACTIN; BETA CATENIN; PACLITAXEL; UVOMORULIN;

ACTIN FILAMENT; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; CYTOSOL; DRUG EFFECT; MICROTUBULE ASSEMBLY; MOLECULAR INTERACTION; NASOPHARYNX CARCINOMA; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

ACTINS; ADENOMATOUS POLYPOSIS COLI PROTEIN; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CADHERINS; CELL SIZE; CYTOSKELETAL PROTEINS; CYTOSKELETON; CYTOSOL; HUMAN; MICROTUBULES; NASOPHARYNGEAL NEOPLASMS; NEOPLASM PROTEINS; PACLITAXEL; PHOSPHORYLATION; SUPPORT, NON-U.S. GOV'T; TUMOR CELLS, CULTURED; TYROSINE;

EID: 0033788821     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-4644(20001215)79:4<542::AID-JCB30>3.0.CO;2-Q     Document Type: Article

References (36)

1. Mechanism of epithelial cell-cell adhesion and cell compaction revealed by high-resolution tracking of E-cadherin-green fluorescence protein
2. Differential molecular interactions of β-catenin and plakoglobin in adhesion, signaling and cancer
3. The Ras-related GTPase Rac1 binds tubulin
4. Evaluation of a tetrazolium-based semiautomated colorimetric assay: Assessment of chemosensitivity testing
5. Tyrosine phosphorylation and cadherin/catenin function
6. Comparative effects of Taxol and taxotere on two different human carcinoma cell lines
7. Microtubule organization and its involvement in the biogenetic pathways of plasma membrane proteins in Caco-2 intestinal epithelial cells
8. The Dbl-related protein, Lfc, localizes to microtubules and mediates the activation of Rac signaling pathways in cells
9. Apico-nuclear organization of microtubules does not specify protein delivery from the trans-Golgi network to different membrane domains in polarized epithelial cells
10. Dynamics of cadherin/catenin complex formation: Novel protein interactions and pathways of complex assembly
11. Calcium-dependent cell-cell adhesion molecules (cadherins): Subclass specificities and possible involvement of actin bundles
12. Interaction of the Rho family small G proteins with kinectin, an anchoring protein of kinesin motor
13. The interactions of APC, E-cadherin and β-catenin in tumor development and progression
14. Mitotic block induced in HeLa cells by low concentrations of paclitaxel (Taxol) results in abnormal mitotic exit and apoptotic cell death
15. Microtubules and actin filaments: Dynamic targets for cancer chemotherapy
16. Microtubule actin cross-linking factor (MACF): A hybrid of dystonin and dystrophin that can interact with the actin and microtubule cytoskeletons
17. Establishment and characterization of two nasopharyngeal carcinoma cell lines
18. Paclitaxel inhibits progression of mitotic cells to G1 phase by interference with spindle formation without affecting other microtubule functions during anaphase and telephase
19. E-, P-, and N-cadherin are co-expressed in the nasopharyngeal carcinoma cell line TW-039
20. Taxol: An antimitotic agent with a new mechanism of action
21. E-cadherin/catenin/cytoskeleton complex: A regulator of cancer invasion
22. Microtubule perturbation retards both the direct and the indirect apical pathway but does not affect sorting of plasma membrane proteins in intestinal epithelial cells (Caco-2)
23. Spatial and temporal dissection of immediate and early events following cadherin-mediated epithelial cell adhesion
24. The adenomatous polyposis coli tumor suppressor protein localizes to plasma membrane sites involved in active cell migration
25. Kinetics of desmosome assembly in Madin-Darby canine kidney epithelial cells: Temporal and spatial regulation of desmoplakin organization and stabilization upon cell-cell contact. I. Biochemical analysis
26. Cloning and characterization of GEF-H1, a microtubule-associated guanine nucleotide exchange factor for Rac and Rho GTPases
27. Binding of GSK3β to the APC-β-catenin complex and regulation of complex assembly
28. Disruption of microtubules reveals two independent apical targeting mechanisms for G-protein-coupled receptors in polarized renal epithelial cells
29. Promotion of microtubule assembly in vitro by Taxol
30. Cadherin cell adhesion receptors as a morphogenetic regulator
31. Cdc42-interacting protein 4 mediates binding of the Wiskott-Aldrich syndrome protein to microtubules
32. Differential Taxol-dependent arrest of transformed and nontransformed cells in the G1 phase of the cell cycle, and specific-related mortality of transformed cells
33. Molecular linkage between cadherins and actin filaments in cell-cell adherens junctions
34. A study of some variables in a tetrazolium dye (MTT) based assay for cell growth and chemosensitivity
35. Taxol-induced mitotic block triggers rapid onset of a P53-independent apoptotic pathway
36. Microtubule integrity is necessary for the epithelial barrier function of cultured thyroid cell monolayers