Post-transcriptional deregulation of myc genes in lung cancer cell lines

American Journal of Respiratory Cell and Molecular Biology

Volumn 23, Issue 4, 2000, Pages 560-565

  Bernasconi, N L ^a   Wormhoudt, T A M ^a   Laird Offringa, I A ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL LINE; FOS GENE; GENE AMPLIFICATION; GENE OVEREXPRESSION; GENETIC TRANSCRIPTION; LUNG CANCER; MESSENGER RNA; ONCOGENE MYC; PROTO ONCOGENE;

EID: 0033788541     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/ajrcmb.23.4.4233     Document Type: Article

References (35)

1. Myc family oncogenes in the development of normal and neoplastic cells
2. c-Myc target genes involved in cell growth, apoptosis, and metabolism
3. The role of MYC, JUN, and FOS oncogenes in human lung cancer
4. Regulation of nuclear oncogenes expressed in lung cancer cell lines
5. Metabolism of c-myc gene products: c-Myc mRNA and protein expression in the cell cycle
6. What determines the instability of c-myc protooncogene mRNA?
7. Posttranscriptional mechanisms are responsible for accumulation of truncated c-myc RNAs in murine plasma cell tumors
8. Truncation of cxon 1 from the c-myc gene results in prolonged c-myc mRNA stability
9. Regulation of N-myc transcript stability in human neuroblastoma and retinobtastoma cells
10. Extreme instability of myc mRNA in normal and transformed human cells
11. Interleukin-3 mRNA stabilization by a trans-acting mechanism in autocrine tumors lacking interleukin-3 gene rearrangements
12. GM-CSF and oncogene mRNA stabilities are independently regulated in trans in a mouse monocytic tumor
13. Binding of a 40-kDa protein to the N-myc 3'-untranslated region correlates with enhanced N-myc expression in human neuroblastoma
14. Coexpression pattern of c-myc associated genes in a small cell lung cancer cell line with high steady state c-myc transcription
15. Multiple mechanisms for transcriptional regulation of the myc gene family in small-cell lung cancer
16. Poly(A) tail shortening is the translation-dependent step in c-myc mRNA degradation
17. Rapid c-myc mRNA degradation does not require (A + U)-rich sequences or complete translation of the mRNA
18. Human cells and cell cultures: Availability, authentication and future prospects
19. NCI-Navy Medical Oncology Branch cell line data base
20. Differential activity of ELAV-like RNA-binding proteins in human neuroblastoma
21. Similarities and differences in the regulation of N-myc and c-myc genes in murine embryonal carcinoma cells
22. AU-rich elements: Characterization and importance in mRNA degradation
23. mRNA stability in mammalian cells
24. Removal of poly(A) and consequent degradation of c-fos mRNA facilitated by 3' AU-rich sequences
25. Multiple regulatory steps control histone mRNA concentrations
26. Changes in the stability of a human H3 histone mRNA during the HeLa cell cycle
27. c-myc RNA degradation in growing and differentiating cells: Possible alternate pathways
28. Activity of a 40 kDa RNA-binding protein correlates with MYCN and c-fos mRNA stability in human neuroblastoma
29. Molecular analysis of the HuD gene encoding a paraneoplastic encephalomyelitis antigen in human lung cancer cell lines
30. Embryonic lethal abnormal visual RNA-binding proteins involved in growth, differentiation, and posttranscriptional gene expression
31. Overexpression of HuR, a nuclear-cytoplasmic shuttling protein, increases the in vivo stability of ARE-containing mRNAs
32. Amplification and expression of the c-myc oncogene in human lung cancer cell lines
33. Human small-cell lung cancers show amplification and expression of the N-myc gene
34. Expression and amplificalion of myc gene family in small cell lung cancer and its relation to biological characteristics