Activity of a 40 kDa RNA-binding protein correlates with MYCN and c-fos mRNA stability in human neuroblastoma

European Journal of Cancer

Volumn 33, Issue 12, 1997, Pages 2064-2067

  Chagnovich, D ^a   Cohn, S L ^b  

^a NORTHWESTERN UNIVERSITY   (United States)

^b CHILDREN'S MEMORIAL HOSPITAL   (United States)

Author keywords

c fos; mRNA stability; MYCN; Neuroblastoma; RNA binding protein

Indexed keywords

MESSENGER RNA; RNA BINDING PROTEIN;

CHILDHOOD CANCER; CONFERENCE PAPER; GENE EXPRESSION; HALF LIFE TIME; HUMAN; HUMAN CELL; NEUROBLASTOMA; NEUROBLASTOMA CELL; NUCLEOTIDE SEQUENCE; ONCOGENE C FOS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RNA BINDING; RNA DEGRADATION;

BINDING SITES; HUMANS; NEOPLASM PROTEINS; NEUROBLASTOMA; PROTO-ONCOGENE PROTEINS C-FOS; PROTO-ONCOGENE PROTEINS C-MYC; RNA, MESSENGER; RNA-BINDING PROTEINS; SEQUENCE ANALYSIS, RNA; TUMOR CELLS, CULTURED;

EID: 0031409334     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-8049(97)00208-6     Document Type: Conference Paper

References (25)

1. Young J. L. Jr, Miller R. W. Incidence of malignant tumors in U. S. children. J Pediatr. 86:1975;254-258.
2. Biedler J. L., Helson L., Spengler B. A. Morphology and growth, tumorigenicity, and cytogenetics of human neuroblastoma cells in continuous culture. Cancer Res. 33:1973;2643-2652.
3. Ciccarone V., Spengler B. A., Meyers M. B., Biedler J. L., Ross R. A. Phenotypic diversification in human neuroblastoma cells: expression of distinct neural crest lineages. Cancer Res. 49:1989;219-225.
4. Ross R. A., Spengler B. A., Biedler J. L. Coordinate morphological and biochemical interconversion of human neuroblastoma cells. J Natl Cancer Inst. 77:1983;741-749.
5. Foley J, Cohn SL, Salwen HR, et al. Differential expression of N-myc in phenotypically distinct subclones of a human neuroblastoma cell line. Cancer Res 1991, 51, 6338-6345.
6. Michitsch R. W., Biedler J. L., Melera P. W. Modulation of N-myc expression, but not tumorigenicity, accompanies phenotypic conversion of neuroblastoma cells in prolonged culture. Prog Clin Biol Res. 271:1988;103-120.
7. Biedler J. L., Bossart E., Ross R. A., Spengler B. A. Loss of neuronal and malignant properties in transdifferentiated substrate-adherent (S-types) human neuroblastoma cells correlates with decreased MYCN expression. Proc Am Assoc Cancer Res. 33:1992;29.
8. Sadee W, Yu VC, Richards ML, et al. Expression of neurotransmitter receptors and myc proto-oncogenes in subclones of a human neuroblastoma cell line. Cancer Res 1987, 47, 5207-5212.
9. Rajagopalan L. E., Malter J. S. Modulation of granulocyte-macrophage colony-stimulating factor mRNA stability in vitro by the adenosine-uridine binding factor. J Biol Chem. 269:1994;23882-23888.
10. Malter J. S. Identification of an AUUUA-specific messenger RNA binding protein. Science. 246:1989;664-666.
11. Bernstein P., Peltz S. W., Ross J. The poly(A)-poly(A)-binding protein complex is a major determinant of mRNA stability in vitro. Mol Cell Biol. 9:1989;659-670.
12. Brewer G. An A + U-rich element RNA-binding factor regulates c-myc mRNA stability in vitro. Mol Cell Biol. 11:1991;2460-2466.
13. Zhang W, Wagner BJ, Ehrenman K, et al. Purification, characterization, and cDNA cloning of an AU-rich element RNA-binding protein, AUF1. Mol Cell Biol 1993, 13, 7652-7665.
14. Bohjanen P. R., Petryniak B., June C. H., Thompson C. B., Lindsten T. An inducible cytoplasmic factor (AU-B) binds selectively to AUUUA multimers in the 3′ untranslated region of lymphokine mRNA. Mol Cell Biol. 11:1991;3288-3295.
15. Raj N. B., Pitha P. M. 65-kDa protein binds to destabilizing sequences in the IFN-beta mRNA coding and 3′UTR. FASEB J. 7:1993;702-710.
16. Schuler G. D., Cole M. D. GM-CSF and oncogene mRNA stabilities are independently regulated in trans in a mouse monocytic tumor. Cell. 55:1988;1115-1122.
17. Chomczynski P., Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-choroform extraction. Anal Biochem. 162:1987;156-159.
18. Cohn SL, Salwen H, Quasney MW, et al. Prolonged N-myc protein half-life in a neuroblastoma cell line lacking N-myc amplification. Oncogene 1990, 5, 1821-1827.
19. Chen C. A., Shyu A. Selective degradation of early-response-gene mRNAs: functional analyses of sequence features of the AU-rich elements. Mol Cell Biol. 14:1994;8471-8482.
20. Milligan J. F., Groebe D. R., Witherell G. W., Uhlenbeck O. C. Oligoribonucleotide synthesis using T7 RNA polymerase and synthetic DNA template. Nucleic Acids Res. 15:1987;8783-8798.
21. Stanton L. W., Schwab M., Bishop J. M. Nucleotide sequence of the human N-myc gene. Proc Natl Acad Sci USA. 83:1986;1772-1776.
22. You Y., Chen C. A., Shyu A. U-rich sequence-binding proteins (URBPs) interacting with a 20-nucleotide U-rich sequence in the 3′ untranslated region of FOS mRNA may be involved in the first step of FOS mRNA degradation. Mol Cell Biol. 12:1992;2931-2940.
23. Bernstein P., Ross J. Poly(A), poly(A) binding protein and the regulation of mRNA stability. Trends Biochem Sci. 14:1989;373-377.
24. Lagnado C. A., Brown C. Y., Goodall G. J. AUUUA is not sufficient to promote poly(A) shortening and degradation of an mRNA: the functional sequence within AU-rich elements may be UUAUUUA(U/A)(U/A). Mol Cell Biol. 14:1994;7984-7995.
25. Zubiaga A. M., Belasco J. G., Greenberg M. E. The nonamer UUAUUUAUU is the key AU-rich sequence motif that mediates mRNA degradation. Mol Cell Biol. 15:1995;2219-2230.